{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone-High+Dose+Quadrivalent", "query": { "intervention": "Fluzone-High Dose Quadrivalent" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 56, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone-High+Dose+Quadrivalent&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T00:03:43.188Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03698279", "title": "Safety and Immunogenicity of Different Dosages of High-Dose Quadrivalent Influenza Vaccine in Children 6 Months to 17 Years of Age", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "High-Dose Quadrivalent Influenza Vaccine (QIV-HD) 30 μg (split-virion, inactivated)", "type": "BIOLOGICAL" }, { "name": "High-Dose Quadrivalent Influenza Vaccine (QIV-HD) 45 μg, (split-virion, inactivated)", "type": "BIOLOGICAL" }, { "name": "High-Dose Quadrivalent Influenza Vaccine (QIV-HD) 60 µg (split-virion, inactivated)", "type": "BIOLOGICAL" }, { "name": "Fluarix Quadrivalent Influenza vaccine (Unadjuvanted QIV-SD) (Inactivated)", "type": "BIOLOGICAL" }, { "name": "FLUAD Pediatric (adjuvanted TIV) (Surface Antigen, Inactivated)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Months to 17 Years" }, "enrollment_count": 665, "start_date": "2018-10-09", "completion_date": "2019-10-16", "has_results": true, "last_update_posted_date": "2022-04-04", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 13, "location_summary": "San Diego, California • Miami, Florida • Atlanta, Georgia + 8 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "El Dorado", "state": "Kansas" }, { "city": "Newton", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03698279" }, { "nct_id": "NCT04077424", "title": "Senescent Immunity in Elders and Vaccine Responses (SILVER)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Flu Vaccine" ], "interventions": [ { "name": "Fluzone-High Dose Quadrivalent", "type": "BIOLOGICAL" }, { "name": "Fluad", "type": "BIOLOGICAL" }, { "name": "Flublock", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": "125 Years", "sex": "ALL", "summary": "65 Years to 125 Years" }, "enrollment_count": 10, "start_date": "2019-10-21", "completion_date": "2020-02-01", "has_results": true, "last_update_posted_date": "2022-07-12", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04077424" }, { "nct_id": "NCT05650554", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5413", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-12-12", "completion_date": "2024-04-02", "has_results": false, "last_update_posted_date": "2025-03-19", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 28, "location_summary": "Chula Vista, California • Gardena, California • Long Beach, California + 24 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Gardena", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05650554" }, { "nct_id": "NCT02860039", "title": "High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hematopoietic Cell Transplantation Recipient", "Malignant Neoplasm", "Influenza" ], "interventions": [ { "name": "Trivalent Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Vanderbilt-Ingram Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "3 Years to 17 Years" }, "enrollment_count": 170, "start_date": "2016-09", "completion_date": "2024-09", "has_results": true, "last_update_posted_date": "2024-10-22", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 9, "location_summary": "San Francisco, California • Kansas City, Missouri • Cincinnati, Ohio + 6 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02860039" }, { "nct_id": "NCT04613206", "title": "High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Immunization; Infection", "Transplantation Infection", "Influenza", "Solid Organ Transplant" ], "interventions": [ { "name": "High Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Standard Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 396, "start_date": "2021-01-11", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04613206" }, { "nct_id": "NCT04109222", "title": "Collection of Serum Samples From Children and Older Adults Receiving the 2019-2020 Formulations of Fluzone® Quadrivalent and Fluzone® High-Dose Influenza Vaccines, Respectively", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, no preservative (0.5-mL), 2019-2020 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose vaccine, 2019-2020 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": "83 Years", "sex": "ALL", "summary": "6 Months to 83 Years" }, "enrollment_count": 90, "start_date": "2019-09-30", "completion_date": "2019-12-10", "has_results": true, "last_update_posted_date": "2025-09-12", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 2, "location_summary": "Bardstown, Kentucky • Salt Lake City, Utah", "locations": [ { "city": "Bardstown", "state": "Kentucky" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04109222" }, { "nct_id": "NCT01827462", "title": "Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages (SLVP015 2007-2017)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Trivalent, inactivated influenza vaccine (TIV)", "type": "BIOLOGICAL" }, { "name": "Quadrivalent, inactivated influenza vaccine (IIV4)", "type": "BIOLOGICAL" }, { "name": "High-Dose Trivalent, inactivated influenza vaccine (TIV High-Dose)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 136, "start_date": "2007-10", "completion_date": "2017-03", "has_results": true, "last_update_posted_date": "2017-07-11", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01827462" }, { "nct_id": "NCT05050318", "title": "Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza Immunization", "Healthy Volunteers" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2021-2022 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2021-2022 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": null, "sex": "ALL", "summary": "6 Months and older" }, "enrollment_count": 90, "start_date": "2021-09-08", "completion_date": "2021-11-10", "has_results": true, "last_update_posted_date": "2025-09-12", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 2, "location_summary": "Bardstown, Kentucky • Salt Lake City, Utah", "locations": [ { "city": "Bardstown", "state": "Kentucky" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05050318" }, { "nct_id": "NCT01946438", "title": "Study of Fluzone® Quadrivalent, Fluzone® Intradermal, and Fluzone® High-Dose Influenza Virus Vaccines in Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Fluzone® Quadrivalent, Influenza Virus Vaccine (2013-2014 formulation),", "type": "BIOLOGICAL" }, { "name": "Fluzone® Intradermal, Influenza Virus Vaccine (2013-2014 formulation),", "type": "BIOLOGICAL" }, { "name": "Fluzone® High-Dose, Influenza Virus Vaccine (2013-2014 formulation)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2013-09", "completion_date": "2014-07", "has_results": true, "last_update_posted_date": "2014-09-25", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 4, "location_summary": "Santa Rosa, California • Council Bluffs, Iowa • Metairie, Louisiana + 1 more", "locations": [ { "city": "Santa Rosa", "state": "California" }, { "city": "Council Bluffs", "state": "Iowa" }, { "city": "Metairie", "state": "Louisiana" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01946438" }, { "nct_id": "NCT05007041", "title": "Simultaneous RZV and aIIV4 Vaccination", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain", "Quality of Life", "Injection Site Reaction", "Adverse Drug Event" ], "interventions": [ { "name": "FLUAD® Quadrivalent", "type": "BIOLOGICAL" }, { "name": "Fluzone® High-Dose Quadrivalent", "type": "BIOLOGICAL" }, { "name": "SHINGRIX®", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 267, "start_date": "2021-09-21", "completion_date": "2023-06-08", "has_results": true, "last_update_posted_date": "2024-07-11", "last_synced_at": "2026-09-04T00:03:43.188Z", "location_count": 2, "location_summary": "Baltimore, Maryland • Durham, North Carolina", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05007041" } ] }