{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Folate&page=15", "query": { "intervention": "Folate", "page": 15 }, "page_size": 10 }, "pagination": { "page": 15, "page_size": 10, "total_count": 1046, "total_pages": 105, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Folate&page=16&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Folate&page=14&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-29T10:06:11.494Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00055432", "title": "Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ovarian Cancer", "Peritoneal Cancer" ], "interventions": [ { "name": "Gemzar and Alimta", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2006-09-15", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00055432" }, { "nct_id": "NCT02312219", "title": "PET/CT Imaging Companion Study To ACTG A5314", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "HIV", "Inflammation", "Atherosclerosis" ], "interventions": [ { "name": "Folic Acid", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Low Dose Methotrexate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 35, "start_date": "2014-11", "completion_date": "2016-12-08", "has_results": true, "last_update_posted_date": "2019-02-06", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02312219" }, { "nct_id": "NCT00003671", "title": "Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia" ], "interventions": [ { "name": "asparaginase", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "cytarabine", "type": "DRUG" }, { "name": "daunorubicin hydrochloride", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "mercaptopurine", "type": "DRUG" }, { "name": "methotrexate", "type": "DRUG" }, { "name": "thioguanine", "type": "DRUG" }, { "name": "vincristine sulfate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 59, "start_date": "1998-12", "completion_date": "2009-02", "has_results": false, "last_update_posted_date": "2014-07-25", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 50, "location_summary": "Tucson, Arizona • Palo Alto, California • Sacramento, California + 43 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003671" }, { "nct_id": "NCT00000714", "title": "An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pneumonia, Pneumocystis Carinii", "HIV Infections" ], "interventions": [ { "name": "Trimetrexate glucuronate", "type": "DRUG" }, { "name": "Leucovorin calcium", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": null, "start_date": null, "completion_date": "2004-07", "has_results": false, "last_update_posted_date": "2021-10-29", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 21, "location_summary": "Miami, Florida • Chicago, Illinois • Indianapolis, Indiana + 15 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000714" }, { "nct_id": "NCT07271316", "title": "Alii Supplement Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nutrient Deficiency", "Happiness", "Digestive Health", "Vulnerability to Disease", "Mood Swings", "Energy" ], "interventions": [ { "name": "Alii Supplement", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Texas Christian University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "25 Years", "sex": "FEMALE", "summary": "18 Years to 25 Years · Female only" }, "enrollment_count": 16, "start_date": "2026-01-12", "completion_date": "2026-04-20", "has_results": true, "last_update_posted_date": "2026-07-13", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07271316" }, { "nct_id": "NCT02629549", "title": "Intraoperative Imaging of Pituitary Adenomas by OTL", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neoplasms", "Pituitary Neoplasms" ], "interventions": [ { "name": "OTL38", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2015-10", "completion_date": "2018-08-03", "has_results": false, "last_update_posted_date": "2019-08-06", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02629549" }, { "nct_id": "NCT00002738", "title": "Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia", "Lymphoma", "Sarcoma" ], "interventions": [ { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "trimetrexate glucuronate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 25, "start_date": "1996-01", "completion_date": "2006-06", "has_results": false, "last_update_posted_date": "2013-03-07", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002738" }, { "nct_id": "NCT01363843", "title": "Complete Neoadjuvant Treatment for REctal Cancer (CONTRE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colon Cancer", "Rectal Cancer" ], "interventions": [ { "name": "FOLFOX6", "type": "DRUG" }, { "name": "RT with concurrent chemotherapy", "type": "RADIATION" }, { "name": "Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "RADIATION", "PROCEDURE" ], "sponsor": "William Sikov MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 39, "start_date": "2010-05", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2020-06-11", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 3, "location_summary": "Pawtucket, Rhode Island • Providence, Rhode Island", "locations": [ { "city": "Pawtucket", "state": "Rhode Island" }, { "city": "Providence", "state": "Rhode Island" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT01363843" }, { "nct_id": "NCT03366493", "title": "The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cervical Intraepithelial Neoplasia Grade 2/3" ], "interventions": [ { "name": "FRD", "type": "COMBINATION_PRODUCT" }, { "name": "Cytology", "type": "OTHER" }, { "name": "HPV testing", "type": "OTHER" }, { "name": "Colposcopy", "type": "PROCEDURE" }, { "name": "ECC", "type": "PROCEDURE" }, { "name": "Biospy", "type": "PROCEDURE" } ], "intervention_types": [ "COMBINATION_PRODUCT", "OTHER", "PROCEDURE" ], "sponsor": "GY Highland Biotech LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "20 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "20 Years to 60 Years · Female only" }, "enrollment_count": 200, "start_date": "2017-12-07", "completion_date": "2018-12-07", "has_results": false, "last_update_posted_date": "2017-12-08", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 1, "location_summary": "Augusta, Georgia", "locations": [ { "city": "Augusta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03366493" }, { "nct_id": "NCT02047474", "title": "Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acinar Cell Adenocarcinoma of the Pancreas", "Duct Cell Adenocarcinoma of the Pancreas", "Stage I Pancreatic Cancer", "Stage IIA Pancreatic Cancer", "Stage IIB Pancreatic Cancer" ], "interventions": [ { "name": "oxaliplatin", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "fluorouracil", "type": "DRUG" }, { "name": "therapeutic conventional surgery", "type": "PROCEDURE" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2014-03-25", "completion_date": "2024-01-14", "has_results": true, "last_update_posted_date": "2026-03-06", "last_synced_at": "2026-10-29T10:06:11.494Z", "location_count": 9, "location_summary": "Fairfield, Connecticut • Guilford, Connecticut • Hartford, Connecticut + 6 more", "locations": [ { "city": "Fairfield", "state": "Connecticut" }, { "city": "Guilford", "state": "Connecticut" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "North Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02047474" } ] }