{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Frequency&page=12",
    "query": {
      "intervention": "Frequency",
      "page": 12
    },
    "page_size": 10
  },
  "pagination": {
    "page": 12,
    "page_size": 10,
    "total_count": 2988,
    "total_pages": 299,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Frequency&page=13&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Frequency&page=11&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-24T05:35:21.212Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04708613",
      "title": "University of Pittsburgh Brain Health Initiative",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Cognitive/Neuropsychological Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Vestibular/Ocular-Motor Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sleep Evaluation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "MRI, High-Resolution",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health & Physical Exam",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Physical Function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Testing and Biomarker Analysis",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Applanation Tonometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "PET brain imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "[C-11]6-OH-BTA-1",
          "type": "DRUG"
        },
        {
          "name": "[F-18]AV-1451",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DRUG"
      ],
      "sponsor": "David Okonkwo, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "29 Years",
        "maximum_age": "59 Years",
        "sex": "MALE",
        "summary": "29 Years to 59 Years · Male only"
      },
      "enrollment_count": 300,
      "start_date": "2019-11-18",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04708613"
    },
    {
      "nct_id": "NCT04950660",
      "title": "Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Adolescent Idiopathic Scoliosis"
      ],
      "interventions": [
        {
          "name": "Caffeine Tablet",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 61,
      "start_date": "2019-12-11",
      "completion_date": "2024-08-01",
      "has_results": true,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04950660"
    },
    {
      "nct_id": "NCT00411723",
      "title": "Safety Study of RTL1000 (Recombinant T Cell Receptor Ligand) in Subjects With Multiple Sclerosis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Multiple Sclerosis, Chronic Progressive",
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "RTL1000 (recombinant T cell receptor ligand)",
          "type": "DRUG"
        },
        {
          "name": "RTL1000 Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Artielle ImmunoTherapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 34,
      "start_date": "2006-12",
      "completion_date": "2009-05",
      "has_results": false,
      "last_update_posted_date": "2009-02-20",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 6,
      "location_summary": "New Haven, Connecticut • Indianapolis, Indiana • Kansas City, Kansas + 3 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00411723"
    },
    {
      "nct_id": "NCT07227350",
      "title": "L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Locally Advanced Basal Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "L19IL2",
          "type": "DRUG"
        },
        {
          "name": "L19TNF",
          "type": "DRUG"
        },
        {
          "name": "L19IL2/L19TNF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Philogen S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2026-06-01",
      "completion_date": "2031-02",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 6,
      "location_summary": "Tampa, Florida • Atlanta, Georgia • Durham, North Carolina + 3 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227350"
    },
    {
      "nct_id": "NCT04992676",
      "title": "Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Disease",
        "Sleep Disorder; Breathing-Related",
        "Sleep Disorder; Insomnia Type"
      ],
      "interventions": [
        {
          "name": "Polysomnograpy",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "actigraphy",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 43,
      "start_date": "2021-08-19",
      "completion_date": "2024-05-02",
      "has_results": false,
      "last_update_posted_date": "2024-07-17",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04992676"
    },
    {
      "nct_id": "NCT02339376",
      "title": "Treating Deep Seizure Foci With Noninvasive Surface Brain Stimulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy, Temporal Lobe"
      ],
      "interventions": [
        {
          "name": "Low-frequency repetitive transcranial magnetic stimulation",
          "type": "DEVICE"
        },
        {
          "name": "High-frequency repetitive transcranial magnetic stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham repetitive transcranial magnetic stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 5,
      "start_date": "2015-01",
      "completion_date": "2021-03-10",
      "has_results": true,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02339376"
    },
    {
      "nct_id": "NCT03544268",
      "title": "Academic-Industrial Partnership for Translation of Acoustic Angiography",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Signs and Symptoms"
      ],
      "interventions": [
        {
          "name": "Acoustic Angiography",
          "type": "DEVICE"
        },
        {
          "name": "Definity",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2019-03-25",
      "completion_date": "2021-05-25",
      "has_results": true,
      "last_update_posted_date": "2022-04-01",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03544268"
    },
    {
      "nct_id": "NCT01549860",
      "title": "Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Insufficiency",
        "Venous Reflux",
        "Lower Extremity Ulcer"
      ],
      "interventions": [
        {
          "name": "MIST Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Celleration, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 156,
      "start_date": "2012-04",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2015-07-30",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Weymouth, Massachusetts",
      "locations": [
        {
          "city": "Weymouth",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01549860"
    },
    {
      "nct_id": "NCT02994108",
      "title": "txt2protect: Using Text Messaging to Increase HPV Vaccination Among Young Sexual Minority Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Papillomavirus"
      ],
      "interventions": [
        {
          "name": "txt2protect",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sexual Health Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "MALE",
        "summary": "18 Years to 25 Years · Male only"
      },
      "enrollment_count": 150,
      "start_date": "2018-01-03",
      "completion_date": "2019-06-30",
      "has_results": true,
      "last_update_posted_date": "2020-07-20",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02994108"
    },
    {
      "nct_id": "NCT06830876",
      "title": "Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Chattanooga Continuum Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sara Peterson-Snyder",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-12-10",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-17",
      "last_synced_at": "2026-10-24T05:35:21.212Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06830876"
    }
  ]
}