{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fructose+solution",
    "query": {
      "intervention": "Fructose solution"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fructose+solution&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T02:02:33.574Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02876796",
      "title": "Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "PD Effects of GS-0976 (NDI-010976) on Fractional DNL"
      ],
      "interventions": [
        {
          "name": "GS-0976",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "1-13C acetate",
          "type": "OTHER"
        },
        {
          "name": "Fructose solution",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Gilead Sciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2015-08",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2016-08-24",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02876796"
    },
    {
      "nct_id": "NCT04623502",
      "title": "An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Cancer",
        "Renal Cell Carcinoma",
        "Clear Cell Carcinoma",
        "Urothelial Carcinoma",
        "Metastatic Kidney Cancer",
        "Metastatic Urothelial Carcinoma",
        "Papillary Renal Cell Carcinoma",
        "Chromophobe Renal Cell Carcinoma",
        "Fumarate Hydratase Deficiency",
        "Succinate Dehydrogenase-Deficient Renal Cell Carcinoma",
        "HLRCC",
        "Hereditary Leiomyomatosis and Renal Cell Cancer"
      ],
      "interventions": [
        {
          "name": "13C-Glucose",
          "type": "OTHER"
        },
        {
          "name": "13C-Acetate",
          "type": "OTHER"
        },
        {
          "name": "13C-Lactate",
          "type": "OTHER"
        },
        {
          "name": "13C-Glutamine",
          "type": "OTHER"
        },
        {
          "name": "13C-Fructose",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2019-09-30",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04623502"
    },
    {
      "nct_id": "NCT07058155",
      "title": "Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Liver Cirrhoses",
        "Portal Hypertension Related to Cirrhosis",
        "Severe Obesity",
        "TIPS"
      ],
      "interventions": [
        {
          "name": "Transjugular Intrahepatic Portosystemic Shunt (TIPS)",
          "type": "PROCEDURE"
        },
        {
          "name": "Sleeve Gastrectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Anti-Obesity Pharmacotherapy (Class Effect)",
          "type": "DRUG"
        },
        {
          "name": "Lifestyle Counseling - Diet & Physical-Activity Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 70,
      "start_date": "2025-12-17",
      "completion_date": "2034-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07058155"
    },
    {
      "nct_id": "NCT02202876",
      "title": "Redox Imbalance and the Development of Cystic Fibrosis Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "Oral Glucose Tolerance Test",
          "type": "OTHER"
        },
        {
          "name": "High Glycemic Index Meal",
          "type": "OTHER"
        },
        {
          "name": "Low Glycemic Index Meal",
          "type": "OTHER"
        },
        {
          "name": "Test Soda",
          "type": "OTHER"
        },
        {
          "name": "Fruit juice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 34,
      "start_date": "2014-11",
      "completion_date": "2018-09-09",
      "has_results": false,
      "last_update_posted_date": "2020-06-04",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02202876"
    },
    {
      "nct_id": "NCT02390180",
      "title": "Sorting of Oral Sensations",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Taste Qualities",
        "Primary Tastes"
      ],
      "interventions": [
        {
          "name": "Tasting solutions",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2014-10",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-05-12",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02390180"
    },
    {
      "nct_id": "NCT03339245",
      "title": "Effects of Dietary Fructose on Gut Microbiota and Fecal Metabolites in Obese Men and Postmenopausal Women: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-Alcoholic Fatty Liver Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Fructose Solution (75 Grams)",
          "type": "OTHER"
        },
        {
          "name": "Glucose Solution (75 grams)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2017-12-05",
      "completion_date": "2018-10-02",
      "has_results": true,
      "last_update_posted_date": "2021-03-26",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03339245"
    },
    {
      "nct_id": "NCT04128839",
      "title": "Impacts of Aronia on Inflammation and the Gut Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Inflammation",
        "Hypertriglyceridemia",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Aronia berry juice",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Sham comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Montana State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 40,
      "start_date": "2019-04-27",
      "completion_date": "2021-12-27",
      "has_results": false,
      "last_update_posted_date": "2024-01-16",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Bozeman, Montana",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04128839"
    },
    {
      "nct_id": "NCT03241706",
      "title": "Liver Glycogen and Hypoglycemia in Humans",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoglycemia; Iatrogenic"
      ],
      "interventions": [
        {
          "name": "Low Fructose",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Somatostatin",
          "type": "DRUG"
        },
        {
          "name": "Insulin",
          "type": "DRUG"
        },
        {
          "name": "Glucagon",
          "type": "DRUG"
        },
        {
          "name": "Dextrose solution",
          "type": "DRUG"
        },
        {
          "name": "High Fructose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jason Winnick",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-08-02",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-25",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241706"
    },
    {
      "nct_id": "NCT04022434",
      "title": "Investigation of Supplemental L-alanine in the Management of Dietary Fructose Intolerance",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fructose Intolerance"
      ],
      "interventions": [
        {
          "name": "Placedo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Alanine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2014-01-07",
      "completion_date": "2020-12-30",
      "has_results": false,
      "last_update_posted_date": "2020-04-15",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04022434"
    },
    {
      "nct_id": "NCT05136092",
      "title": "A Pilot Study to Determine Fructose Uptake by Primary Human Colorectal Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Tumors"
      ],
      "interventions": [
        {
          "name": "Cohort 1: HFCS (fructose) fed",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Cohort 2: D-Xylose (xylose-fed)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2022-02-16",
      "completion_date": "2024-09-27",
      "has_results": false,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-09-13T02:02:33.574Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05136092"
    }
  ]
}