{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Functional+Assessment+of+Cancer+Therapy+-+Brain", "query": { "intervention": "Functional Assessment of Cancer Therapy - Brain" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 52, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Functional+Assessment+of+Cancer+Therapy+-+Brain&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T07:52:05.337Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00031798", "title": "Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Brain and Central Nervous System Tumors", "Cognitive/Functional Effects", "Depression", "Fatigue", "Quality of Life" ], "interventions": [ { "name": "methylphenidate hydrochloride", "type": "DRUG" }, { "name": "quality-of-life assessment", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": null, "start_date": "2002-04-01", "completion_date": "2006-05-01", "has_results": false, "last_update_posted_date": "2021-09-09", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Decatur, Illinois • New Orleans, Louisiana + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Decatur", "state": "Illinois" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Goldsboro", "state": "North Carolina" }, { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00031798" }, { "nct_id": "NCT06865677", "title": "Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Platinum Resistant Epithelial Ovarian Carcinoma", "Recurrent Epithelial Endometrial Carcinoma", "Recurrent Epithelial Cervical Carcinoma" ], "interventions": [ { "name": "Sacituzumab Govitecan", "type": "DRUG" }, { "name": "EKG", "type": "DIAGNOSTIC_TEST" }, { "name": "Brain MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "CT scans", "type": "DIAGNOSTIC_TEST" }, { "name": "Tumor biopsy", "type": "PROCEDURE" }, { "name": "Loperamide", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "Diphenoxylate/Atropine", "type": "DRUG" }, { "name": "Antiemetics", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST", "PROCEDURE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "FEMALE", "summary": "18 Years to 120 Years · Female only" }, "enrollment_count": 2, "start_date": "2025-06-09", "completion_date": "2025-07-01", "has_results": true, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06865677" }, { "nct_id": "NCT00896324", "title": "Intellectual Impairment in Women With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Cognitive Rehabilitation", "type": "BEHAVIORAL" }, { "name": "Active Neurofeedback Training", "type": "BEHAVIORAL" }, { "name": "Neurofeedback Training (placebo / Sham)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "40 Years to 65 Years · Female only" }, "enrollment_count": 50, "start_date": "2009-01-12", "completion_date": "2013-06", "has_results": false, "last_update_posted_date": "2019-05-01", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00896324" }, { "nct_id": "NCT00910039", "title": "Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain Metastases", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cognitive/Functional Effects", "Metastatic Cancer", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "sunitinib malate", "type": "DRUG" }, { "name": "cognitive assessment", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2009-04", "completion_date": "2014-04", "has_results": true, "last_update_posted_date": "2014-09-29", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 3, "location_summary": "Detroit, Michigan • Cleveland, Ohio", "locations": [ { "city": "Detroit", "state": "Michigan" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00910039" }, { "nct_id": "NCT04432597", "title": "HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "HPV Positive Cancer", "Vulvar, Vaginal, Penile, Rectal Cancer", "Anal Cancer", "Oropharyngeal Cancer", "Cervical Cancer" ], "interventions": [ { "name": "PRGN-2009", "type": "BIOLOGICAL" }, { "name": "M7824", "type": "BIOLOGICAL" }, { "name": "EKG", "type": "DIAGNOSTIC_TEST" }, { "name": "CT Scan", "type": "DIAGNOSTIC_TEST" }, { "name": "Brain MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "Biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "DIAGNOSTIC_TEST", "PROCEDURE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 39, "start_date": "2020-08-11", "completion_date": "2026-03-31", "has_results": true, "last_update_posted_date": "2026-08-18", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04432597" }, { "nct_id": "NCT07659652", "title": "Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Breast Cancer, Quality of Life", "Breast Cancer, Metastatic", "Breast Cancer, Metastatic Breast Cancer", "Leptomeningeal Metastasis of Breast Cancer", "Brain Metastases From Breast Cancer" ], "interventions": [ { "name": "Health-Related Quality of Life (QOL) questionnaires", "type": "OTHER" }, { "name": "Medical Chart Review", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2026-10-15", "completion_date": "2035-12-31", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07659652" }, { "nct_id": "NCT05288439", "title": "A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Brain Tumor", "Metastatic Brain Tumor" ], "interventions": [ { "name": "Resting-state functional connectivity MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "Neurocognitive battery with quality-of-life assessment", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "OTHER" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "6 Years to 25 Years" }, "enrollment_count": 30, "start_date": "2022-03-07", "completion_date": "2027-03", "has_results": false, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05288439" }, { "nct_id": "NCT01894061", "title": "NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Adult Giant Cell Glioblastoma", "Adult Glioblastoma", "Adult Gliosarcoma", "Recurrent Adult Brain Tumor" ], "interventions": [ { "name": "Bevacizumab", "type": "BIOLOGICAL" }, { "name": "NovoTTF-l00A", "type": "DEVICE" }, { "name": "Quality of Life Assessment", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "DEVICE", "OTHER" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 25, "start_date": "2013-09-18", "completion_date": "2019-07-01", "has_results": true, "last_update_posted_date": "2025-02-17", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 3, "location_summary": "Cincinnati, Ohio • Cleveland, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01894061" }, { "nct_id": "NCT00389584", "title": "Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Brain and Central Nervous System Tumors", "Cognitive/Functional Effects", "Long-term Effects Secondary to Cancer Therapy in Adults", "Long-term Effects Secondary to Cancer Therapy in Children", "Poor Performance Status", "Unspecified Adult Solid Tumor, Protocol Specific", "Unspecified Childhood Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "cognitive assessment", "type": "PROCEDURE" }, { "name": "management of therapy complications", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "University of California, Davis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "120 Years", "sex": "ALL", "summary": "1 Year to 120 Years" }, "enrollment_count": 30, "start_date": "2002-12", "completion_date": "2006-11", "has_results": false, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 1, "location_summary": "Sacramento, California", "locations": [ { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00389584" }, { "nct_id": "NCT02290834", "title": "Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Impaired Cognition", "Chemo-brain", "Breast Cancer" ], "interventions": [ { "name": "Cognitive, functional and subjective assessments", "type": "OTHER" }, { "name": "MRI", "type": "DEVICE" }, { "name": "PET Scan", "type": "RADIATION" } ], "intervention_types": [ "OTHER", "DEVICE", "RADIATION" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "FEMALE", "summary": "60 Years and older · Female only" }, "enrollment_count": 200, "start_date": "2015-03", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-07-16", "last_synced_at": "2026-09-21T07:52:05.337Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Salem, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Salem", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02290834" } ] }