{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Furosemide+40+mg", "query": { "intervention": "Furosemide 40 mg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 19, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Furosemide+40+mg&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T13:19:18.021Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02030314", "title": "The Management of Resistant Hypertension in Kidney Transplant Patients Using Chlorthalidone", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Resistant Hypertension in Kidney Transplant Patients" ], "interventions": [ { "name": "Chlorthalidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2013-07", "completion_date": "2017-04-12", "has_results": false, "last_update_posted_date": "2017-06-15", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02030314" }, { "nct_id": "NCT05480722", "title": "Central Sodium Sensing: Implications for Blood Pressure Regulation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Salt Sensitivity of Blood Pressure" ], "interventions": [ { "name": "Hypertonic Saline with furosemide", "type": "OTHER" }, { "name": "Hypertonic Saline without furosemide", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Delaware", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 29, "start_date": "2022-06-01", "completion_date": "2025-01-31", "has_results": true, "last_update_posted_date": "2025-12-08", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Newark, Delaware", "locations": [ { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT05480722" }, { "nct_id": "NCT00000620", "title": "Action to Control Cardiovascular Risk in Diabetes (ACCORD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Atherosclerosis", "Cardiovascular Diseases", "Hypercholesterolemia", "Hypertension", "Diabetes Mellitus, Type 2", "Diabetes Mellitus", "Coronary Disease" ], "interventions": [ { "name": "Anti-hyperglycemic Agents", "type": "DRUG" }, { "name": "Anti-hypertensive Agents", "type": "DRUG" }, { "name": "Blinded fenofibrate or placebo plus simvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "40 Years to 79 Years" }, "enrollment_count": 10251, "start_date": "1999-09", "completion_date": "2012-12", "has_results": true, "last_update_posted_date": "2016-11-22", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 6, "location_summary": "Minneapolis, Minnesota • New York, New York • Winston-Salem, North Carolina + 3 more", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "New York", "state": "New York" }, { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000620" }, { "nct_id": "NCT03753204", "title": "Salt-Sensitivity and Immunity Cell Activation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "High Blood Pressure", "Salt; Excess", "Inflammation" ], "interventions": [ { "name": "Furosemide 40 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 20, "start_date": "2021-09-01", "completion_date": "2026-09-15", "has_results": false, "last_update_posted_date": "2025-10-21", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03753204" }, { "nct_id": "NCT05440851", "title": "Platform of Randomized Adaptive Clinical Trials in Critical Illness", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Insufficiency", "Extracorporeal Membrane Oxygenation Complication", "Mechanical Ventilation Pressure High" ], "interventions": [ { "name": "Ultra-Protective Ventilation Facilitated by Extracorporeal Support", "type": "OTHER" }, { "name": "Lung-Protective Ventilation (LPV)", "type": "OTHER" }, { "name": "Driving Pressure-Limited Ventilation (DPL)", "type": "OTHER" }, { "name": "Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)", "type": "OTHER" }, { "name": "Early Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Extended Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Usual care without routine corticosteroids", "type": "DRUG" }, { "name": "Usual care without extending corticosteroids", "type": "DRUG" }, { "name": "Usual care with fludrocortisone", "type": "DRUG" }, { "name": "Usual care without fludrocortisone", "type": "DRUG" }, { "name": "Drug 4 mL:", "type": "DRUG" }, { "name": "Drug 40 mg:", "type": "DRUG" }, { "name": "PEEP-20", "type": "OTHER" }, { "name": "PEEP-AOP", "type": "OTHER" }, { "name": "PEEP-10", "type": "OTHER" }, { "name": "VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation", "type": "OTHER" }, { "name": "Electrical impedance tomography (EIT)", "type": "OTHER" }, { "name": "no treatment / intervention arm is involved.", "type": "OTHER" }, { "name": "Usual care", "type": "OTHER" }, { "name": "Early Routine IMT", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University Health Network, Toronto", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6250, "start_date": "2023-04-30", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-05-07", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 26, "location_summary": "Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05440851" }, { "nct_id": "NCT03136198", "title": "B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure", "Heart Failure Acute", "Acute Cardiac Pulmonary Edema", "Acute Cardiac Failure" ], "interventions": [ { "name": "LUS-guided strategy-of-care", "type": "OTHER" }, { "name": "Usual Care", "type": "OTHER" }, { "name": "Intravenous Loop Diuretic", "type": "DRUG" }, { "name": "Vasodilator", "type": "DRUG" }, { "name": "Non invasive Ventilation (NIV)", "type": "DEVICE" } ], "intervention_types": [ "OTHER", "DRUG", "DEVICE" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 130, "start_date": "2017-07-10", "completion_date": "2019-06-20", "has_results": true, "last_update_posted_date": "2024-06-04", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 6, "location_summary": "Indianapolis, Indiana • Detroit, Michigan • Cleveland, Ohio + 2 more", "locations": [ { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03136198" }, { "nct_id": "NCT06995144", "title": "Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Heart Failure", "Edema", "Pulmonary Congestion", "Fluid Overload" ], "interventions": [ { "name": "Extended Release Torsemide Tablets", "type": "DRUG" }, { "name": "Immedate Release Torsemide Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sarfez Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2025-05-28", "completion_date": "2025-12-30", "has_results": false, "last_update_posted_date": "2026-03-10", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06995144" }, { "nct_id": "NCT03296813", "title": "TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "Torsemide", "type": "DRUG" }, { "name": "Furosemide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2973, "start_date": "2018-07-11", "completion_date": "2022-07-29", "has_results": true, "last_update_posted_date": "2025-10-16", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 60, "location_summary": "Alexander City, Alabama • Huntsville, Alabama • Tucson, Arizona + 51 more", "locations": [ { "city": "Alexander City", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03296813" }, { "nct_id": "NCT01721655", "title": "Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Chronic Lung Disease", "Bronchopulmonary Dysplasia" ], "interventions": [ { "name": "Spironolactone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "West Virginia University Healthcare", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 40, "start_date": "2012-10", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2016-11-30", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01721655" }, { "nct_id": "NCT03837470", "title": "Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Heart Failure With Preserved Ejection Fraction" ], "interventions": [ { "name": "0.9% Sodium Chloride", "type": "DRUG" }, { "name": "Furosemide 40 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Adhish Agarwal", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 14, "start_date": "2019-05-06", "completion_date": "2020-02-20", "has_results": false, "last_update_posted_date": "2021-04-19", "last_synced_at": "2026-09-04T13:19:18.021Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03837470" } ] }