{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Gene+sequencing&page=8", "query": { "intervention": "Gene sequencing", "page": 8 }, "page_size": 10 }, "pagination": { "page": 8, "page_size": 10, "total_count": 556, "total_pages": 56, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Gene+sequencing&page=9&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Gene+sequencing&page=7&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-31T14:46:22.920Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05734430", "title": "Genetics of Appendix Cancer Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Appendix Cancer", "Appendiceal Cancer", "Appendiceal Neoplasms", "Appendiceal Mucinous Neoplasm", "Appendiceal Adenocarcinoma", "Appendiceal Carcinoid Tumor", "Appendiceal Neoplasm Malignant Secondary", "Appendix Adenocarcinoma", "Appendix Mucinous Neoplasm", "Appendix Tumor", "Appendix Cancer Metastatic", "Appendix NET", "Low-Grade Appendix Mucinous Neoplasm", "High Grade Appendix Mucinous Neoplasm", "High Grade Appendix Mucinous Adenocarcinoma" ], "interventions": [ { "name": "Genetic profiling", "type": "GENETIC" }, { "name": "Retrospective tissue procurement", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Andreana Holowatyj, PhD, MSCI", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 700, "start_date": "2022-11-11", "completion_date": "2034-11", "has_results": false, "last_update_posted_date": "2025-04-18", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05734430" }, { "nct_id": "NCT04488393", "title": "Clinical Performance of NIPT in Multiple Gestation Pregnancies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Trisomy 21 in Fetus" ], "interventions": [ { "name": "MaterniT21 PLUS and GENOME Laboratory-Developed Tests", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 2000, "start_date": "2020-03-01", "completion_date": "2022-06-19", "has_results": false, "last_update_posted_date": "2022-12-07", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04488393" }, { "nct_id": "NCT02705404", "title": "A Clinical Test for the Treatment of Multifocal Lung Cancers Using Genome Sequencing", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Neoplasms", "Carcinoma Non-small-cell Lung" ], "interventions": [ { "name": "Multifocal Tissue Banking", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2016-02-11", "completion_date": "2021-11-16", "has_results": false, "last_update_posted_date": "2022-04-14", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02705404" }, { "nct_id": "NCT04518410", "title": "ACTIV-2: A Study for Outpatients With COVID-19", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Coronavirus", "Covid19" ], "interventions": [ { "name": "bamlanivimab 7000mg", "type": "BIOLOGICAL" }, { "name": "BRII-196+BRII-198", "type": "BIOLOGICAL" }, { "name": "AZD7442 (IV)", "type": "BIOLOGICAL" }, { "name": "AZD7442 (IM)", "type": "BIOLOGICAL" }, { "name": "SNG001", "type": "DRUG" }, { "name": "Camostat", "type": "DRUG" }, { "name": "BMS-986414 + BMS-986413", "type": "BIOLOGICAL" }, { "name": "SAB-185 (3,840 Units/kg)", "type": "BIOLOGICAL" }, { "name": "SAB-185 (10,240 Units/kg)", "type": "BIOLOGICAL" }, { "name": "CASIRIVIMAB + IMDEVIMAB", "type": "DRUG" }, { "name": "Placebo for Bamlanivimab 7000mg", "type": "DRUG" }, { "name": "Placebo for Bamlanivimab 700mg", "type": "DRUG" }, { "name": "Placebo for BRII-196+BRII-198", "type": "DRUG" }, { "name": "Placebo for SNG001", "type": "DRUG" }, { "name": "Placebo for Camostat", "type": "DRUG" }, { "name": "Placebo for SAB-185 (low dose)", "type": "DRUG" }, { "name": "Placebo for BMS-986414 + BMS-986413", "type": "DRUG" }, { "name": "Placebo for AZD7442 (IV)", "type": "DRUG" }, { "name": "Placebo for AZD7442 (IM)", "type": "DRUG" }, { "name": "Placebo for SAB-185 (high dose)", "type": "DRUG" }, { "name": "bamlanivimab 700mg", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4044, "start_date": "2020-08-19", "completion_date": "2023-06-20", "has_results": true, "last_update_posted_date": "2024-08-02", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 207, "location_summary": "Anniston, Alabama • Athens, Alabama • Birmingham, Alabama + 143 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Athens", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Cullman", "state": "Alabama" }, { "city": "Jasper", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT04518410" }, { "nct_id": "NCT05188118", "title": "Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Renal Cell Carcinoma" ], "interventions": [ { "name": "Cabozantinib", "type": "DRUG" }, { "name": "Ipilimumab", "type": "DRUG" }, { "name": "Nivolumab", "type": "DRUG" }, { "name": "Lenvatinib", "type": "DRUG" }, { "name": "Everolimus", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Icahn School of Medicine at Mount Sinai", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 10, "start_date": "2023-02-15", "completion_date": "2025-04-30", "has_results": false, "last_update_posted_date": "2026-09-24", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05188118" }, { "nct_id": "NCT03412760", "title": "Hydrops: Diagnosing & Redefining Outcomes With Precision Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hydrops Fetalis", "Birth Defect", "Fetal Anomaly" ], "interventions": [ { "name": "Exome sequencing", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 500, "start_date": "2018-10-11", "completion_date": "2027-02", "has_results": false, "last_update_posted_date": "2026-04-17", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03412760" }, { "nct_id": "NCT01736566", "title": "A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Adults (Full Study and Extension Phase)", "Hypertrophic Cardiomyopathy or Dilated Cardiomyopathy" ], "interventions": [ { "name": "Family History + Whole Genome Sequencing", "type": "OTHER" }, { "name": "Family History Only", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 213, "start_date": "2011-12", "completion_date": "2021-01-02", "has_results": true, "last_update_posted_date": "2024-08-27", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01736566" }, { "nct_id": "NCT05457140", "title": "Multiomic Diagnostics in Youth With Psychosis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Psychosis" ], "interventions": [ { "name": "Genetic: Genomic sequencing and molecular diagnostic results, if any.", "type": "GENETIC" }, { "name": "Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "GENETIC", "DIAGNOSTIC_TEST" ], "sponsor": "Rady Pediatric Genomics & Systems Medicine Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 15, "start_date": "2022-10-10", "completion_date": "2026-08", "has_results": false, "last_update_posted_date": "2024-11-14", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05457140" }, { "nct_id": "NCT04265534", "title": "KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Non-Small Cell Lung Cancer", "Non-squamous Non-small-cell Lung Cancer", "Non-Squamous Non-Small Cell Neoplasm of Lung", "KEAP1 Gene Mutation", "NRF2 Gene Mutation", "NFE2L2 Gene Mutation" ], "interventions": [ { "name": "Telaglenastat", "type": "DRUG" }, { "name": "Carboplatin Chemotherapy", "type": "DRUG" }, { "name": "Pemetrexed Chemotherapy", "type": "DRUG" }, { "name": "Pembrolizumab Immunotherapy", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Folic acid 400 -1000 μg", "type": "DIETARY_SUPPLEMENT" }, { "name": "Vitamin B12 1000 μg", "type": "DIETARY_SUPPLEMENT" }, { "name": "Dexamethasone 4 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL", "DIETARY_SUPPLEMENT" ], "sponsor": "Calithera Biosciences, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2020-07-24", "completion_date": "2022-02-09", "has_results": false, "last_update_posted_date": "2022-09-21", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 102, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Yuma, Arizona + 86 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Yuma", "state": "Arizona" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Fullerton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04265534" }, { "nct_id": "NCT06659458", "title": "Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Cancer - Non Small Cell", "EGFR Exon 19 Deletion Mutation" ], "interventions": [ { "name": "blood draw", "type": "OTHER" }, { "name": "Gene sequencing", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Our Lady of the Lake Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "FEMALE", "summary": "18 Years to 100 Years · Female only" }, "enrollment_count": 20, "start_date": "2025-01-01", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2025-03-20", "last_synced_at": "2026-10-31T14:46:22.920Z", "location_count": 1, "location_summary": "Baton Rouge, Louisiana", "locations": [ { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06659458" } ] }