{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Genome+sequencing&page=5", "query": { "intervention": "Genome sequencing", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 196, "total_pages": 20, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Genome+sequencing&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Genome+sequencing&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-23T00:42:27.956Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00389142", "title": "Identifying Genetic Causes of IC/BPS", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Interstitial Cystitis", "Bladder Pain Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": null, "sex": "ALL", "summary": "1 Year and older" }, "enrollment_count": 1000, "start_date": "2006-01-15", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2025-12-16", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00389142" }, { "nct_id": "NCT07005700", "title": "Rapid Diagnostics for Genetic Disorders in Neonates", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acid Base Disorder" ], "interventions": [ { "name": "Targeted genomic sequencing", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Sharp HealthCare", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "6 Months", "sex": "ALL", "summary": "1 Day to 6 Months" }, "enrollment_count": 100, "start_date": "2025-06-30", "completion_date": "2027-05", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07005700" }, { "nct_id": "NCT07829445", "title": "PRECISE LBCL: Precision Treatment Readiness Through Comprehensive Genomic Sequencing in 1st Line LBCL", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "LBCL", "Comprehensive Genomic", "Precision Treatment" ], "interventions": [ { "name": "Standard of Care (SOC)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2027-02-25", "completion_date": "2029-06-30", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07829445" }, { "nct_id": "NCT06910670", "title": "Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cholangiocarcinoma", "Colorectal Cancer", "Multiple Myeloma" ], "interventions": [ { "name": "Standard developed materials", "type": "OTHER" }, { "name": "Genetics Advisor Decision Aid", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 197, "start_date": "2025-04-03", "completion_date": "2026-11-01", "has_results": false, "last_update_posted_date": "2026-09-25", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06910670" }, { "nct_id": "NCT06647641", "title": "The CurePSP Genetics Program", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "PSP", "PSP - Progressive Supranuclear Palsy", "Corticobasal Syndrome", "Corticobasal Syndrome(CBS)", "Corticobasal Degeneration Syndrome", "Corticobasal Degeneration", "Corticobasal Degeneration (CBD)", "Corticobasal Syndrome (CBS)", "MSA", "MSA - Multiple System Atrophy", "MSA-C", "Multiple System Atrophy", "Multiple System Atrophy (MSA) With Orthostatic Hypotension", "Multiple System Atrophy - Cerebellar Subtype (MSA-C)", "Multiple System Atrophy - Parkinsonian Subtype (MSA-P)", "Multiple System Atrophy, Cerebellar Type", "Multiple System Atrophy, Parkinsonian Type", "Progressive Supranuclear Palsy", "Progressive Supranuclear Palsy(PSP)", "Progressive Supranuclear Palsy (PSP)" ], "interventions": [ { "name": "Whole genome sequencing will be performed at the NIH", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 1000, "start_date": "2024-10-08", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2026-01-14", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06647641" }, { "nct_id": "NCT01567722", "title": "Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Cancer", "Lymphoma" ], "interventions": [ { "name": "DNA analysis", "type": "GENETIC" }, { "name": "RNA analysis", "type": "GENETIC" }, { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "polymorphism analysis", "type": "GENETIC" }, { "name": "biologic sample preservation procedure", "type": "OTHER" }, { "name": "flow cytometry", "type": "OTHER" }, { "name": "medical chart review", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "AIDS Malignancy Consortium", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 114, "start_date": "2013-01-02", "completion_date": "2022-01-14", "has_results": true, "last_update_posted_date": "2023-03-16", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 14, "location_summary": "La Jolla, California • Los Angeles, California • Washington D.C., District of Columbia + 9 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01567722" }, { "nct_id": "NCT00950118", "title": "Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Congenital Diaphragmatic Hernia" ], "interventions": [], "intervention_types": [], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 3000, "start_date": "2005-06", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-10-05", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 13, "location_summary": "Chicago, Illinois • Ann Arbor, Michigan • St Louis, Missouri + 9 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Omaha", "state": "Nebraska" }, { "city": "Manhasset", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00950118" }, { "nct_id": "NCT02699190", "title": "LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts 1", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus-Merzbacher-Like Disease, 1", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 236, "start_date": "2017-01-06", "completion_date": "2024-10-31", "has_results": true, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02699190" }, { "nct_id": "NCT02927158", "title": "Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Undiagnosed Disease" ], "interventions": [], "intervention_types": [], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "100 Years", "sex": "ALL", "summary": "Up to 100 Years" }, "enrollment_count": 300, "start_date": "2016-08", "completion_date": "2040-08", "has_results": false, "last_update_posted_date": "2026-03-10", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02927158" }, { "nct_id": "NCT01087320", "title": "Genome Medical Sequencing for Gene Discovery", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Intellectual Disabilities", "Congenital Anomaly", "Rare Disorders" ], "interventions": [], "intervention_types": [], "sponsor": "National Human Genome Research Institute (NHGRI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Weeks", "maximum_age": "99 Years", "sex": "ALL", "summary": "4 Weeks to 99 Years" }, "enrollment_count": 2000, "start_date": "2010-02-18", "completion_date": null, "has_results": false, "last_update_posted_date": "2026-10-22", "last_synced_at": "2026-10-23T00:42:27.956Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01087320" } ] }