{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Glass+Ionomer",
    "query": {
      "intervention": "Glass Ionomer"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Glass+Ionomer&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T04:25:19.834Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04822233",
      "title": "A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Hall Technique (HT)",
          "type": "DEVICE"
        },
        {
          "name": "Modified Hall Technique (MHT)",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Technique (CT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "5 Years to 8 Years"
      },
      "enrollment_count": 132,
      "start_date": "2023-06-01",
      "completion_date": "2025-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04822233"
    },
    {
      "nct_id": "NCT07213661",
      "title": "LT Comparative Effectiveness of 2 Caries Treatments",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "A \"simple medical strategy\" consisting of silver diamine fluoride (SDF)",
          "type": "DEVICE"
        },
        {
          "name": "A \"typical dental strategy\" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 480,
      "start_date": "2025-10-08",
      "completion_date": "2030-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07213661"
    },
    {
      "nct_id": "NCT03916926",
      "title": "Older Adult Effectiveness of 2 Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "A \"simple medical strategy\" consisting of silver diamine fluoride (SDF)",
          "type": "DEVICE"
        },
        {
          "name": "B \"typical dental strategy\" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 568,
      "start_date": "2019-09-18",
      "completion_date": "2024-06-07",
      "has_results": true,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916926"
    },
    {
      "nct_id": "NCT06173167",
      "title": "Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Disorders Hard Tissues of Teeth",
        "Dental Diseases"
      ],
      "interventions": [
        {
          "name": "Crowns self-adhesively luted",
          "type": "DEVICE"
        },
        {
          "name": "Crowns conventionally cemented",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ivoclar Vivadent AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2024-01-08",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-03-28",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06173167"
    },
    {
      "nct_id": "NCT01827098",
      "title": "A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Necrosis",
        "Disorder of Tooth Development"
      ],
      "interventions": [
        {
          "name": "Endodontic Regeneration",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "6 Years to 25 Years"
      },
      "enrollment_count": 45,
      "start_date": "2012-10",
      "completion_date": "2023-06-07",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01827098"
    },
    {
      "nct_id": "NCT03304184",
      "title": "The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Quality of Life",
        "Cervical Abrasion"
      ],
      "interventions": [
        {
          "name": "Photac-fil",
          "type": "DEVICE"
        },
        {
          "name": "Biodentine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-09-28",
      "completion_date": "2019-10-09",
      "has_results": true,
      "last_update_posted_date": "2021-07-19",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03304184"
    },
    {
      "nct_id": "NCT04933331",
      "title": "Early Caries Lesion Management Observational Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Initial Caries",
        "Arrested Dental Caries",
        "Cavitated Caries",
        "Dental Caries",
        "Dental Caries in Children"
      ],
      "interventions": [
        {
          "name": "Curodont Repair Fluoride Plus",
          "type": "DRUG"
        },
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride varnish",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "CareQuest Institute for Oral Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 744,
      "start_date": "2020-12-07",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-24",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 4,
      "location_summary": "Dothan, Alabama • Westborough, Massachusetts • Bend, Oregon + 1 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Westborough",
          "state": "Massachusetts"
        },
        {
          "city": "Bend",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04933331"
    },
    {
      "nct_id": "NCT01268605",
      "title": "Postoperative Hypersensitivity Randomized Comparative Effectiveness Research Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Restoration with a dentin bonding agent (DBA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Restoration with a resin modified glass ionomer liner (RMGI)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Pearl Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "15 Years to 60 Years"
      },
      "enrollment_count": 341,
      "start_date": "2010-09",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2014-09-19",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 41,
      "location_summary": "Phoeniz, Arizona • Newport Beach, California • Boulder, Colorado + 37 more",
      "locations": [
        {
          "city": "Phoeniz",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Sanford",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01268605"
    },
    {
      "nct_id": "NCT04528134",
      "title": "Orthodontic Varnish Microbiology Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Dental Plaque",
        "Dental White Spot"
      ],
      "interventions": [
        {
          "name": "Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish",
          "type": "DEVICE"
        },
        {
          "name": "5% Sodium Fluoride Varnish",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "27 Years",
        "sex": "ALL",
        "summary": "12 Years to 27 Years"
      },
      "enrollment_count": 38,
      "start_date": "2022-02-07",
      "completion_date": "2025-07-01",
      "has_results": true,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04528134"
    },
    {
      "nct_id": "NCT03442309",
      "title": "Comparative Effectiveness of School-based Caries Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 7418,
      "start_date": "2019-02-01",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-26",
      "last_synced_at": "2026-09-11T04:25:19.834Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03442309"
    }
  ]
}