{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Glucagon+Sensitivity+Testing",
    "query": {
      "intervention": "Glucagon Sensitivity Testing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T23:59:32.934Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06592261",
      "title": "Graded Insulin Suppression Test P&F",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Insulin Resistance",
        "Hyperinsulinemia",
        "Obesity",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Insulin regular, 2.0-3.2 mU/m2/min (euinsulinemia)",
          "type": "DRUG"
        },
        {
          "name": "Insulin regular, 32 mU/m2/min (hyperinsulinemia)",
          "type": "DRUG"
        },
        {
          "name": "Octreotide Acetate, 6-45 ng/kg/min",
          "type": "DRUG"
        },
        {
          "name": "Dextrose 20 % in Water",
          "type": "DRUG"
        },
        {
          "name": "Glucagon, 0-0.5 ng/kg/min",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2024-09-16",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06592261"
    },
    {
      "nct_id": "NCT00488423",
      "title": "Glucose Metabolism in the Immediate and Short Term Follow up After Bariatric Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diabetes",
        "Gastric Bypass"
      ],
      "interventions": [
        {
          "name": "Mixed Meal Tolerance test, Hyperglycemic clamp",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "19 Years to 65 Years"
      },
      "enrollment_count": 21,
      "start_date": "2006-11",
      "completion_date": "2008-11",
      "has_results": false,
      "last_update_posted_date": "2011-06-22",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00488423"
    },
    {
      "nct_id": "NCT06657209",
      "title": "Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Diabetes",
        "Type 2 Diabetes",
        "Pre Diabetes"
      ],
      "interventions": [
        {
          "name": "Insulin resistance testing",
          "type": "PROCEDURE"
        },
        {
          "name": "OGTT",
          "type": "PROCEDURE"
        },
        {
          "name": "Fat biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "DXA scan",
          "type": "RADIATION"
        },
        {
          "name": "MRI",
          "type": "PROCEDURE"
        },
        {
          "name": "1H-MRS",
          "type": "PROCEDURE"
        },
        {
          "name": "Tirzepatide",
          "type": "DRUG"
        },
        {
          "name": "Pioglitazone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 104,
      "start_date": "2025-01-13",
      "completion_date": "2027-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • Stanford, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06657209"
    },
    {
      "nct_id": "NCT04428866",
      "title": "Mechanisms of Post-Bariatric Hypoglycemia",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoglycemia"
      ],
      "interventions": [
        {
          "name": "Continuous Glucose Monitoring",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "activity monitor",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Mixed meal tolerance test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Glucagon Sensitivity Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hypoglycemic Hyperinsulinemic Clamp",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "analysis of fecal microbiome",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Joslin Diabetes Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 105,
      "start_date": "2020-02-26",
      "completion_date": "2024-09",
      "has_results": false,
      "last_update_posted_date": "2024-01-05",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04428866"
    },
    {
      "nct_id": "NCT02971202",
      "title": "Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus",
        "Maturity-Onset Diabetes of the Young, Type 2",
        "MODY2",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Hyperinsulinemic, euglycemic clamp",
          "type": "DRUG"
        },
        {
          "name": "20% dextrose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "51 Years",
        "sex": "ALL",
        "summary": "13 Years to 51 Years"
      },
      "enrollment_count": 33,
      "start_date": "2016-12",
      "completion_date": "2019-02",
      "has_results": true,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02971202"
    },
    {
      "nct_id": "NCT03547427",
      "title": "Glucagon Counterregulation in Type 1 Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Basal insulin alone",
          "type": "OTHER"
        },
        {
          "name": "Basal pramlintide and reduced basal insulin",
          "type": "OTHER"
        },
        {
          "name": "CGM",
          "type": "OTHER"
        },
        {
          "name": "Acetaminophen test",
          "type": "OTHER"
        },
        {
          "name": "Insulin-induced hypoglycemia",
          "type": "OTHER"
        },
        {
          "name": "Exercise-induced hypoglycemia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 13,
      "start_date": "2018-05-20",
      "completion_date": "2019-03-11",
      "has_results": false,
      "last_update_posted_date": "2022-03-28",
      "last_synced_at": "2026-09-02T23:59:32.934Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03547427"
    }
  ]
}