{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=GnRH+antagonist+%28Acyline%29", "query": { "intervention": "GnRH antagonist (Acyline)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 8, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-04T04:48:38.498Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00983554", "title": "Metabolic Effects of Steroids in Obese Men", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity", "Insulin Resistance" ], "interventions": [ { "name": "Anastrazole", "type": "DRUG" }, { "name": "Testosterone", "type": "DRUG" }, { "name": "Dutasteride", "type": "DRUG" }, { "name": "GnRH antagonist", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "24 Years", "maximum_age": "51 Years", "sex": "MALE", "summary": "24 Years to 51 Years · Male only" }, "enrollment_count": 57, "start_date": "2005-06", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2011-03-16", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 2, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00983554" }, { "nct_id": "NCT02758431", "title": "Cardiovascular Outcomes of Low Testosterone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypogonadism" ], "interventions": [ { "name": "Acyline", "type": "DRUG" }, { "name": "Placebo Gel", "type": "DRUG" }, { "name": "Placebo Tablet", "type": "DRUG" }, { "name": "Testosterone Gel", "type": "DRUG" }, { "name": "Arimidex", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "MALE", "summary": "18 Years to 75 Years · Male only" }, "enrollment_count": 232, "start_date": "2016-07-01", "completion_date": "2023-01-04", "has_results": false, "last_update_posted_date": "2024-10-10", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT02758431" }, { "nct_id": "NCT01215292", "title": "ITT4 Intratesticular Hormonal Milieu in Man (ITT4)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Healthy Males" ], "interventions": [ { "name": "Acyline", "type": "DRUG" }, { "name": "Testosterone gel", "type": "DRUG" }, { "name": "ketoconazole 400", "type": "DRUG" }, { "name": "Ketoconazole 800", "type": "DRUG" }, { "name": "Dutasteride", "type": "DRUG" }, { "name": "Anastrozole", "type": "DRUG" }, { "name": "Placebo ketoconazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "MALE", "summary": "18 Years to 50 Years · Male only" }, "enrollment_count": 46, "start_date": "2011-01", "completion_date": "2012-03", "has_results": true, "last_update_posted_date": "2014-03-31", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01215292" }, { "nct_id": "NCT00156650", "title": "Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Contraception" ], "interventions": [ { "name": "Acyline", "type": "DRUG" }, { "name": "Testosterone Gel", "type": "DRUG" }, { "name": "Depo-Medroxyprogesterone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "MALE", "summary": "18 Years to 55 Years · Male only" }, "enrollment_count": 23, "start_date": "2004-12", "completion_date": "2005-07", "has_results": false, "last_update_posted_date": "2008-09-19", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00156650" }, { "nct_id": "NCT00603187", "title": "ACY-7 Oral Administration of Acyline", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Acyline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "MALE", "summary": "18 Years to 50 Years · Male only" }, "enrollment_count": 4, "start_date": "2008-01", "completion_date": "2008-02", "has_results": true, "last_update_posted_date": "2011-06-09", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00603187" }, { "nct_id": "NCT01327495", "title": "PROS-2 Dose Response Effects of Exogenous Testosterone on the Prostate", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "placebo acyline", "type": "OTHER" }, { "name": "placebo gel", "type": "OTHER" }, { "name": "Testosterone 1% gel 1.25 g", "type": "DRUG" }, { "name": "Testosterone 1% gel 2.5 g", "type": "DRUG" }, { "name": "Testosterone 1% gel 5.0 g", "type": "DRUG" }, { "name": "testosterone 1% gel 10 g", "type": "DRUG" }, { "name": "testosterone 1% gel 15 g", "type": "DRUG" }, { "name": "Acyline", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "55 Years", "sex": "MALE", "summary": "25 Years to 55 Years · Male only" }, "enrollment_count": 62, "start_date": "2011-10", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2017-10-05", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01327495" }, { "nct_id": "NCT00471185", "title": "ACY-6 Oral Administration of Acyline", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Contraception" ], "interventions": [ { "name": "Acyline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "MALE", "summary": "18 Years to 50 Years · Male only" }, "enrollment_count": 9, "start_date": "2007-06", "completion_date": "2007-08", "has_results": false, "last_update_posted_date": "2010-12-03", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00471185" }, { "nct_id": "NCT00470990", "title": "Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypogonadism" ], "interventions": [ { "name": "GnRH antagonist (Acyline)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "MALE", "summary": "18 Years to 75 Years · Male only" }, "enrollment_count": 40, "start_date": "2002-10", "completion_date": "2008-06", "has_results": false, "last_update_posted_date": "2011-04-20", "last_synced_at": "2026-10-04T04:48:38.498Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00470990" } ] }