{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=GnRh+%28Leuprolide%29&page=8", "query": { "intervention": "GnRh (Leuprolide)", "page": 8 }, "page_size": 10 }, "pagination": { "page": 8, "page_size": 10, "total_count": 248, "total_pages": 25, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=GnRh+%28Leuprolide%29&page=9&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=GnRh+%28Leuprolide%29&page=7&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-10T05:07:52.864Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04484818", "title": "Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Prostate Carcinoma" ], "interventions": [ { "name": "Darolutamide", "type": "DRUG" }, { "name": "Goserelin Acetate", "type": "DRUG" }, { "name": "Leuprolide Acetate", "type": "DRUG" }, { "name": "Placebo Administration", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Triptorelin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "ECOG-ACRIN Cancer Research Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 27, "start_date": "2021-03-01", "completion_date": "2028-05-31", "has_results": false, "last_update_posted_date": "2026-07-28", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 115, "location_summary": "Duarte, California • Los Angeles, California • Palo Alto, California + 88 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04484818" }, { "nct_id": "NCT03678025", "title": "Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Castration Levels of Testosterone", "Metastatic Prostatic Adenocarcinoma", "Stage IV Prostate Cancer AJCC v8", "Stage IVA Prostate Cancer AJCC v8", "Stage IVB Prostate Cancer AJCC v8" ], "interventions": [ { "name": "Abiraterone", "type": "DRUG" }, { "name": "Bicalutamide", "type": "DRUG" }, { "name": "Degarelix", "type": "DRUG" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Flutamide", "type": "DRUG" }, { "name": "Goserelin Acetate", "type": "DRUG" }, { "name": "Histrelin Acetate", "type": "DRUG" }, { "name": "Leuprolide Acetate", "type": "DRUG" }, { "name": "Nilutamide", "type": "DRUG" }, { "name": "Orchiectomy", "type": "PROCEDURE" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Radical Prostatectomy", "type": "PROCEDURE" }, { "name": "Triptorelin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER", "RADIATION" ], "sponsor": "SWOG Cancer Research Network", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 1273, "start_date": "2018-09-24", "completion_date": "2036-10-01", "has_results": false, "last_update_posted_date": "2026-10-08", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 334, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 253 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03678025" }, { "nct_id": "NCT02058706", "title": "LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Adenocarcinoma of the Prostate", "Recurrent Prostate Cancer", "Stage IV Prostate Cancer" ], "interventions": [ { "name": "enzalutamide", "type": "DRUG" }, { "name": "bicalutamide", "type": "DRUG" }, { "name": "orchiectomy", "type": "PROCEDURE" }, { "name": "leuprolide acetate", "type": "DRUG" }, { "name": "goserelin acetate", "type": "DRUG" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER" ], "sponsor": "Barbara Ann Karmanos Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 71, "start_date": "2014-05", "completion_date": "2021-03-01", "has_results": true, "last_update_posted_date": "2023-05-10", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 4, "location_summary": "Birmingham, Alabama • Detroit, Michigan • Columbus, Ohio", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02058706" }, { "nct_id": "NCT00206375", "title": "Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypothyroidism" ], "interventions": [ { "name": "Growth hormone", "type": "DRUG" }, { "name": "Growth hormone treatment and puberty", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "8 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "8 Years to 17 Years" }, "enrollment_count": 16, "start_date": "2003-05", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2020-10-30", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00206375" }, { "nct_id": "NCT00116220", "title": "Study of External Beam Radiation Therapy With and Without Hormonal Therapy to Treat Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Flutamide (Eulexin) and Lupron or Zoladex", "type": "DRUG" }, { "name": "External Beam Radiotherapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "41 Years", "maximum_age": null, "sex": "MALE", "summary": "41 Years and older · Male only" }, "enrollment_count": 206, "start_date": "1995-09", "completion_date": "2015-02", "has_results": false, "last_update_posted_date": "2022-01-06", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00116220" }, { "nct_id": "NCT00734279", "title": "Follicle-Stimulating Hormone (FSH) and the Onset of Puberty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Delayed Puberty", "Precocious Puberty" ], "interventions": [ { "name": "Leuprolide Acetate - Early Puberty Leuprolide Visit", "type": "DRUG" }, { "name": "Ganirelix - Early Puberty Ganirelix Visit", "type": "DRUG" }, { "name": "Ganirelix - Delayed Puberty Ganirelix Visit", "type": "DRUG" }, { "name": "Leuprolide Acetate- Delayed Puberty Leuprolide Visit", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 11, "start_date": "2006-03", "completion_date": "2010-12", "has_results": false, "last_update_posted_date": "2017-12-26", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00734279" }, { "nct_id": "NCT02452931", "title": "Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Precocious Puberty, Central" ], "interventions": [ { "name": "Leuprolide Acetate 45 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tolmar Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "9 Years", "sex": "ALL", "summary": "2 Years to 9 Years" }, "enrollment_count": 64, "start_date": "2015-08-31", "completion_date": "2018-09-05", "has_results": true, "last_update_posted_date": "2020-06-02", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 10, "location_summary": "San Diego, California • Hollywood, Florida • Jacksonville, Florida + 7 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02452931" }, { "nct_id": "NCT00283062", "title": "Adjuvant Leuprolide With or Without Docetaxel in High Risk Prostate Cancer After Radical Prostatectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Prostatic Neoplasms" ], "interventions": [ { "name": "Docetaxel (TAXOTERE®) Chemotherapy", "type": "DRUG" }, { "name": "Leuprolide acetate ( ELIGARD®) Hormonal Therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 228, "start_date": "2005-12", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2012-01-26", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00283062" }, { "nct_id": "NCT00203996", "title": "Polycystic Ovary Syndrome (PCOS) and Sleep Apnea", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Polycystic Ovary Syndrome", "Obstructive Sleep Apnea" ], "interventions": [ { "name": "continuous positive airway pressure (CPAP)", "type": "DEVICE" }, { "name": "depot leuprolide plus estrogen/progestin replacement", "type": "DRUG" }, { "name": "pioglitazone", "type": "DRUG" }, { "name": "REM frag", "type": "PROCEDURE" }, { "name": "SWS supp", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "DRUG", "PROCEDURE" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 37, "start_date": "2003-09", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2023-03-21", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00203996" }, { "nct_id": "NCT00028769", "title": "S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "bicalutamide", "type": "DRUG" }, { "name": "estramustine", "type": "DRUG" }, { "name": "etoposide", "type": "DRUG" }, { "name": "flutamide", "type": "DRUG" }, { "name": "goserelin", "type": "DRUG" }, { "name": "leuprolide", "type": "DRUG" }, { "name": "nilutamide", "type": "DRUG" }, { "name": "paclitaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "SWOG Cancer Research Network", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 41, "start_date": "2001-12", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2013-07-16", "last_synced_at": "2026-10-10T05:07:52.864Z", "location_count": 91, "location_summary": "Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 60 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00028769" } ] }