{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Goal-directed+Therapeutic+Protocol",
    "query": {
      "intervention": "Goal-directed Therapeutic Protocol"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Goal-directed+Therapeutic+Protocol&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T11:17:13.316Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03511976",
      "title": "Adaptive Response to Intervention (RTI) for Students With ADHD",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [
        {
          "name": "Tier 1 Classroom Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Daily Report Card (DRC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced DRC (DRC-E)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stimulant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Florida International University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2018-05-14",
      "completion_date": "2023-10-21",
      "has_results": false,
      "last_update_posted_date": "2025-08-07",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Buffalo, New York",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03511976"
    },
    {
      "nct_id": "NCT00372411",
      "title": "Robotic Assisted Upper-Limb Neurorehabilitation in Stroke Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Robot-Assisted Therapy - MIT-MANUS System",
          "type": "DEVICE"
        },
        {
          "name": "Intensive Comparison Therapy",
          "type": "OTHER"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 127,
      "start_date": "2005-12",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2014-01-13",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 5,
      "location_summary": "West Haven, Connecticut • Gainesville, Florida • Baltimore, Maryland + 2 more",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00372411"
    },
    {
      "nct_id": "NCT05934487",
      "title": "PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure NYHA Class II",
        "Heart Failure NYHA Class III",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Cordella™ Pulmonary Artery Sensor System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Endotronix, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1750,
      "start_date": "2023-11-29",
      "completion_date": "2033-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 45,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • San Francisco, California + 35 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Pensacola",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05934487"
    },
    {
      "nct_id": "NCT04164667",
      "title": "Telehealth Pilot for Veterans with Chronic Multi-Symptom Illness.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Multisymptom Illness"
      ],
      "interventions": [
        {
          "name": "Mental and physical (MAP) training intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "War Related Illness and Injury Study Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2017-11-17",
      "completion_date": "2021-07-06",
      "has_results": false,
      "last_update_posted_date": "2024-11-04",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04164667"
    },
    {
      "nct_id": "NCT07262138",
      "title": "Active Surveillance in Older Women With ER+ Breast Cancer",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Early Stage Estrogen Receptor (ER) Positive Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Active Surveillance",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "70 Years and older · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2025-11-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07262138"
    },
    {
      "nct_id": "NCT03451799",
      "title": "Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "GBM",
        "Glioblastoma"
      ],
      "interventions": [
        {
          "name": "Ketogenic Diet",
          "type": "OTHER"
        },
        {
          "name": "Standard-of-care radiation",
          "type": "RADIATION"
        },
        {
          "name": "Standard-of-care Temozolomide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "Jethro Hu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2018-04-13",
      "completion_date": "2024-04-29",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03451799"
    },
    {
      "nct_id": "NCT02354742",
      "title": "Echo vs. EGDT in Severe Sepsis and Septic Shock",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Sepsis",
        "Septic Shock"
      ],
      "interventions": [
        {
          "name": "Echo guided fluid resuscitation",
          "type": "OTHER"
        },
        {
          "name": "EGDT fluid resuscitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Intermountain Health Care, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2014-12",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2018-07-16",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02354742"
    },
    {
      "nct_id": "NCT00624650",
      "title": "Hemodynamics and Extravascular Lung Water in Acute Lung Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Lung Injury"
      ],
      "interventions": [
        {
          "name": "Diuresis (furosemide) part I",
          "type": "DRUG"
        },
        {
          "name": "Fluid Bolus (crystalloid or albumin)",
          "type": "OTHER"
        },
        {
          "name": "Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine)",
          "type": "DRUG"
        },
        {
          "name": "Dobutamine",
          "type": "DRUG"
        },
        {
          "name": "Concentrate all drips and nutrition",
          "type": "OTHER"
        },
        {
          "name": "Diuresis (furosemide) part II",
          "type": "DRUG"
        },
        {
          "name": "Dialysis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2008-02",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 3,
      "location_summary": "Clackamas, Oregon • Portland, Oregon",
      "locations": [
        {
          "city": "Clackamas",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00624650"
    },
    {
      "nct_id": "NCT00714441",
      "title": "Reducing Distress and Improving Self-Care in Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Type 2"
      ],
      "interventions": [
        {
          "name": "Lifestyle and Activities Education Program (LEAP-AHEAD)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Computer Automated Self-Management (CASM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Computer Automated Self-Management and Problem Solving Therapy (CAPS)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 392,
      "start_date": "2008-07",
      "completion_date": "2011-11",
      "has_results": false,
      "last_update_posted_date": "2012-04-19",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00714441"
    },
    {
      "nct_id": "NCT04983498",
      "title": "Enhanced Recovery Pathway for Endoscopy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Enhanced Recovery Pathway",
        "Endoscopy"
      ],
      "interventions": [
        {
          "name": "Ondansetron 4 MG",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringers, Intravenous",
          "type": "DRUG"
        },
        {
          "name": "Early Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Early PO Intake",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-09-01",
      "completion_date": "2022-01-01",
      "has_results": false,
      "last_update_posted_date": "2021-12-15",
      "last_synced_at": "2026-09-15T11:17:13.316Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04983498"
    }
  ]
}