{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Group+1-ACL+reconstruction",
    "query": {
      "intervention": "Group 1-ACL reconstruction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Group+1-ACL+reconstruction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T07:59:42.650Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03141801",
      "title": "Blood Flow Restriction to Improve Muscle Strength After ACL Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise with BLAST Leg Press System",
          "type": "OTHER"
        },
        {
          "name": "Concentric Exercise with BLAST Leg Press System",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "14 Years to 30 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-08-25",
      "completion_date": "2018-11-21",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03141801"
    },
    {
      "nct_id": "NCT03626857",
      "title": "MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Neuromuscular Electrical Stimulation (NMES)",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise (ECC)",
          "type": "OTHER"
        },
        {
          "name": "Neuromuscular Electrical Stimulation (NMES) placebo",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise (ECC) placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "14 Years to 45 Years"
      },
      "enrollment_count": 135,
      "start_date": "2019-02-22",
      "completion_date": "2025-01-09",
      "has_results": true,
      "last_update_posted_date": "2026-01-02",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03626857"
    },
    {
      "nct_id": "NCT06973785",
      "title": "Non-Narcotic Pain Control After ACL Reconstruction",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Injuries"
      ],
      "interventions": [
        {
          "name": "dispense of study drug",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "15 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-07-15",
      "completion_date": "2027-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 3,
      "location_summary": "Coral Springs, Florida • Garfield, Ohio • Strongsville, Ohio",
      "locations": [
        {
          "city": "Coral Springs",
          "state": "Florida"
        },
        {
          "city": "Garfield",
          "state": "Ohio"
        },
        {
          "city": "Strongsville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06973785"
    },
    {
      "nct_id": "NCT07090616",
      "title": "KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament (ACL) Reconstruction Surgery"
      ],
      "interventions": [
        {
          "name": "Arm 1-Kronos brace",
          "type": "DEVICE"
        },
        {
          "name": "Arm 2-Breg T-Scope brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2025-02-11",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07090616"
    },
    {
      "nct_id": "NCT04285853",
      "title": "Are Opioids Needed After ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Oxycodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "14 Years to 40 Years"
      },
      "enrollment_count": 98,
      "start_date": "2020-09-16",
      "completion_date": "2022-09-19",
      "has_results": true,
      "last_update_posted_date": "2023-10-11",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Tucker, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Tucker",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04285853"
    },
    {
      "nct_id": "NCT04390035",
      "title": "BFRT in Adolescents After ACL Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction using Delfi Personalized Tourniquet System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Healthcare of Atlanta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 120,
      "start_date": "2020-09-23",
      "completion_date": "2023-04",
      "has_results": false,
      "last_update_posted_date": "2021-08-02",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04390035"
    },
    {
      "nct_id": "NCT05949177",
      "title": "Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Graded Exposure and Mindfulness Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Waitlist Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-10-30",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05949177"
    },
    {
      "nct_id": "NCT03243162",
      "title": "Improving ACL Reconstruction Outcomes: CBPT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury",
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Sprain",
        "ACL Tear"
      ],
      "interventions": [
        {
          "name": "CBPT-ACLR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 90,
      "start_date": "2017-07-01",
      "completion_date": "2020-04-17",
      "has_results": false,
      "last_update_posted_date": "2020-05-20",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 2,
      "location_summary": "Garfield Heights, Ohio • Nashville, Tennessee",
      "locations": [
        {
          "city": "Garfield Heights",
          "state": "Ohio"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03243162"
    },
    {
      "nct_id": "NCT06006624",
      "title": "Exparel vs Block for ACL Reconstruction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "ACL",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Exparel 30 mL",
          "type": "DRUG"
        },
        {
          "name": "0.5% bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "iPACK block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 154,
      "start_date": "2023-08-21",
      "completion_date": "2024-10-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06006624"
    },
    {
      "nct_id": "NCT06603051",
      "title": "The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Repair"
      ],
      "interventions": [
        {
          "name": "Cryoneurolysis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Virtua Health, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2024-08-28",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-15T07:59:42.650Z",
      "location_count": 2,
      "location_summary": "Burlington, New Jersey • Cherry Hill, New Jersey",
      "locations": [
        {
          "city": "Burlington",
          "state": "New Jersey"
        },
        {
          "city": "Cherry Hill",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06603051"
    }
  ]
}