{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Guselkumab+Dose+2", "query": { "intervention": "Guselkumab Dose 2" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 28, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Guselkumab+Dose+2&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T08:34:07.820Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03466411", "title": "A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Guselkumab Dose 1", "type": "DRUG" }, { "name": "Guselkumab Dose 2", "type": "DRUG" }, { "name": "Guselkumab Dose 3", "type": "DRUG" }, { "name": "Guselkumab Dose 4", "type": "DRUG" }, { "name": "Guselkumab Dose 5", "type": "DRUG" }, { "name": "Guselkumab", "type": "DRUG" }, { "name": "Ustekinumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1409, "start_date": "2018-04-13", "completion_date": "2028-01-28", "has_results": true, "last_update_posted_date": "2026-08-31", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 109, "location_summary": "Dothan, Alabama • Mobile, Alabama • Tucson, Arizona + 83 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03466411" }, { "nct_id": "NCT05535738", "title": "Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Skin Inflammation", "Allergic Contact Dermatitis" ], "interventions": [ { "name": "Squaric Acid Dibutyl Ester", "type": "DRUG" }, { "name": "Known patch test allergens", "type": "OTHER" }, { "name": "Dupilumab", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Ustekinumab", "type": "DRUG" }, { "name": "Guselkumab", "type": "DRUG" }, { "name": "Canakinumab", "type": "DRUG" }, { "name": "Sarilumab", "type": "DRUG" }, { "name": "Triamcinolone Acetonide", "type": "DRUG" }, { "name": "Betamethasone Valerate", "type": "DRUG" }, { "name": "Fluticasone Propionate", "type": "DRUG" }, { "name": "Microneedle", "type": "DEVICE" }, { "name": "Suction blistering", "type": "DEVICE" }, { "name": "Skin punch biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "DEVICE", "PROCEDURE" ], "sponsor": "Wei-Che Ko", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 45, "start_date": "2022-11-15", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 1, "location_summary": "Worcester, Massachusetts", "locations": [ { "city": "Worcester", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05535738" }, { "nct_id": "NCT05784129", "title": "A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4, "start_date": "2023-02-21", "completion_date": "2023-10-10", "has_results": true, "last_update_posted_date": "2025-04-29", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 9, "location_summary": "San Diego, California • Naples, Florida • Macon, Georgia + 6 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Naples", "state": "Florida" }, { "city": "Macon", "state": "Georgia" }, { "city": "Shreveport", "state": "Louisiana" }, { "city": "Asheville", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05784129" }, { "nct_id": "NCT04882098", "title": "A Study of Guselkumab in Participants With Active Psoriatic Arthritis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Arthritis, Psoriatic" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1054, "start_date": "2021-06-17", "completion_date": "2027-10-06", "has_results": true, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 23, "location_summary": "Birmingham, Alabama • Flagstaff, Arizona • Glendale, Arizona + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Flagstaff", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Palma", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04882098" }, { "nct_id": "NCT04033445", "title": "A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Ulcerative Colitis" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Guselkumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1064, "start_date": "2019-09-26", "completion_date": "2027-07-16", "has_results": true, "last_update_posted_date": "2026-08-31", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 52, "location_summary": "Lancaster, California • Los Angeles, California • Colorado Springs, Colorado + 42 more", "locations": [ { "city": "Lancaster", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04033445" }, { "nct_id": "NCT03628924", "title": "A Study to Evaluate the Efficacy, Safety, and Tolerability of Guselkumab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa (HS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hidradenitis Suppurativa" ], "interventions": [ { "name": "Guselkumab dose 1", "type": "DRUG" }, { "name": "Guselkumab dose 2", "type": "DRUG" }, { "name": "Guselkumab dose 3", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 184, "start_date": "2018-09-04", "completion_date": "2020-05-22", "has_results": true, "last_update_posted_date": "2025-02-04", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 20, "location_summary": "Birmingham, Alabama • Largo, Florida • Ocala, Florida + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Largo", "state": "Florida" }, { "city": "Ocala", "state": "Florida" }, { "city": "Orange Park", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03628924" }, { "nct_id": "NCT06408935", "title": "Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen-Cilag Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2024-04-17", "completion_date": "2028-03-06", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 4, "location_summary": "San Francisco, California • Chicago, Illinois • St Louis, Missouri + 1 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06408935" }, { "nct_id": "NCT05923073", "title": "A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "2 Years to 17 Years" }, "enrollment_count": 120, "start_date": "2024-03-13", "completion_date": "2028-08-14", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 14, "location_summary": "Los Angeles, California • Hartford, Connecticut • Atlanta, Georgia + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05923073" }, { "nct_id": "NCT05242471", "title": "A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Guselkumab", "type": "BIOLOGICAL" }, { "name": "Golimumab", "type": "BIOLOGICAL" }, { "name": "JNJ-78934804", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 703, "start_date": "2022-07-22", "completion_date": "2029-11-05", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 90, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 79 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Apple Valley", "state": "California" }, { "city": "Arcadia", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05242471" }, { "nct_id": "NCT03649971", "title": "A Study of Guselkumab in Participants With Familial Adenomatous Polyposis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adenomatous Polyposis Coli" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 77, "start_date": "2018-11-19", "completion_date": "2022-03-23", "has_results": false, "last_update_posted_date": "2025-02-03", "last_synced_at": "2026-09-15T08:34:07.820Z", "location_count": 18, "location_summary": "Phoenix, Arizona • Duarte, California • New Haven, Connecticut + 13 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03649971" } ] }