{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HD+Vaccine", "query": { "intervention": "HD Vaccine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 57, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HD+Vaccine&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T01:23:31.742Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05650554", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5413", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-12-12", "completion_date": "2024-04-02", "has_results": false, "last_update_posted_date": "2025-03-19", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 28, "location_summary": "Chula Vista, California • Gardena, California • Long Beach, California + 24 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Gardena", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05650554" }, { "nct_id": "NCT02872311", "title": "Open-Label Influenza Vaccine Evaluation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Immune Response" ], "interventions": [ { "name": "High Dose Influenza vaccine", "type": "BIOLOGICAL" }, { "name": "Adjuvanted Influenza vaccine", "type": "BIOLOGICAL" }, { "name": "Standard Dose Influenza vaccine", "type": "BIOLOGICAL" }, { "name": "Recombinant Influenza vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Marshfield Clinic Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": "74 Years", "sex": "ALL", "summary": "65 Years to 74 Years" }, "enrollment_count": 179, "start_date": "2016-09", "completion_date": "2018-09", "has_results": true, "last_update_posted_date": "2025-12-10", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 1, "location_summary": "Marshfield, Wisconsin", "locations": [ { "city": "Marshfield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT02872311" }, { "nct_id": "NCT06029933", "title": "Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Influenza", "Community-acquired Pneumonia", "Cardiovascular Events" ], "interventions": [ { "name": "Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4)", "type": "BIOLOGICAL" }, { "name": "High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Kaiser Permanente", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 1500000, "start_date": "2023-08-17", "completion_date": "2028-05", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 1, "location_summary": "Oakland, California", "locations": [ { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06029933" }, { "nct_id": "NCT06060457", "title": "A Study to Evaluate the Safety and Immune Response of mRNA-1345, a Vaccine Targeting Respiratory Syncytial Virus (RSV), When Co-administered With a Fluzone HD, in Adults ≥65 Years of Age", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Respiratory Syncytial Virus" ], "interventions": [ { "name": "Placebo", "type": "BIOLOGICAL" }, { "name": "mRNA-1345", "type": "BIOLOGICAL" }, { "name": "Fluzone HD", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "ModernaTX, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 1900, "start_date": "2023-09-25", "completion_date": "2024-06-07", "has_results": true, "last_update_posted_date": "2025-07-30", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 34, "location_summary": "Scottsdale, Arizona • Dublin, California • Riverside, California + 29 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Dublin", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06060457" }, { "nct_id": "NCT06431607", "title": "A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza, Human" ], "interventions": [ { "name": "F2G22B/DL001Z", "type": "BIOLOGICAL" }, { "name": "F2H23D/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23B/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23H/DL001Z", "type": "BIOLOGICAL" }, { "name": "FDQ23A-NH (Flu D-QIV)", "type": "COMBINATION_PRODUCT" }, { "name": "GSK5800544A", "type": "BIOLOGICAL" }, { "name": "Flu D-TIV", "type": "COMBINATION_PRODUCT" }, { "name": "F2H23A/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23G/DL001Z", "type": "BIOLOGICAL" }, { "name": "Fluzone HD Quadrivalent", "type": "COMBINATION_PRODUCT" }, { "name": "Fluzone HD", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "BIOLOGICAL", "COMBINATION_PRODUCT" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 845, "start_date": "2024-05-23", "completion_date": "2025-06-04", "has_results": true, "last_update_posted_date": "2026-03-10", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 18, "location_summary": "Hialeah, Florida • Miami, Florida • Chicago, Illinois + 14 more", "locations": [ { "city": "Hialeah", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Valparaiso", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06431607" }, { "nct_id": "NCT05553301", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5407 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5407", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 560, "start_date": "2022-10-03", "completion_date": "2024-01-19", "has_results": false, "last_update_posted_date": "2025-01-24", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 23, "location_summary": "Rolling Hills Estates, California • San Diego, California • DeLand, Florida + 16 more", "locations": [ { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05553301" }, { "nct_id": "NCT05426174", "title": "Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Influenza Immunization", "Healthy Volunteers" ], "interventions": [ { "name": "mRNA NA vaccine", "type": "BIOLOGICAL" }, { "name": "High Dose Quadrivalent Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 233, "start_date": "2022-06-09", "completion_date": "2024-01-03", "has_results": false, "last_update_posted_date": "2025-09-15", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 6, "location_summary": "Huntsville, Alabama • Phoenix, Arizona • San Diego, California + 3 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Melbourne", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05426174" }, { "nct_id": "NCT05624606", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5410", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza vaccine RIV4", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza Standard Dose QIV-SD", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza High Dose QIV-HD", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-11-28", "completion_date": "2024-03-28", "has_results": false, "last_update_posted_date": "2025-03-18", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 23, "location_summary": "Huntington Park, California • Long Beach, California • North Hollywood, California + 19 more", "locations": [ { "city": "Huntington Park", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05624606" }, { "nct_id": "NCT00775450", "title": "Influenza Vaccine Revaccination in Ambulatory Elderly Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza", "Orthomyxovirus Infection", "Myxovirus Infection" ], "interventions": [ { "name": "Influenza Virus Vaccine USP Trivalent Types A and B", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 807, "start_date": "2008-10", "completion_date": "2009-07", "has_results": true, "last_update_posted_date": "2013-12-31", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 28, "location_summary": "Hoover, Alabama • Mobile, Alabama • Chandler, Arizona + 24 more", "locations": [ { "city": "Hoover", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775450" }, { "nct_id": "NCT04613206", "title": "High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Immunization; Infection", "Transplantation Infection", "Influenza", "Solid Organ Transplant" ], "interventions": [ { "name": "High Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Standard Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 396, "start_date": "2021-01-11", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-09-03T01:23:31.742Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04613206" } ] }