{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HFA-134a", "query": { "intervention": "HFA-134a" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 63, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HFA-134a&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-12T02:28:58.758Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02031640", "title": "A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants >=12 Years Old With Persistent Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Beclomethasone dipropionate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Albuterol/salbutamol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1113, "start_date": "2013-12", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2021-11-09", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 94, "location_summary": "Costa Mesa, California • Huntington Beach, California • Long Beach, California + 77 more", "locations": [ { "city": "Costa Mesa", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02031640" }, { "nct_id": "NCT00393991", "title": "Comparison of New Combination Inhaler (FlutiForm HFA MDI 100/10 µg) Versus Fluticasone and Formoterol Administered Alone, and Placebo, in Patients With Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Fluticasone propionate/formoterol fumarate 100/10", "type": "DRUG" }, { "name": "Fluticasone propionate 100", "type": "DRUG" }, { "name": "Formoterol fumarate 10", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "SkyePharma AG", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 475, "start_date": "2006-07", "completion_date": "2008-04", "has_results": false, "last_update_posted_date": "2011-06-23", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 47, "location_summary": "Pell City, Alabama • Scottsdale, Arizona • Cypress, California + 42 more", "locations": [ { "city": "Pell City", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Cypress", "state": "California" }, { "city": "Encinitas", "state": "California" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00393991" }, { "nct_id": "NCT01188577", "title": "Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Asthma", "Bronchospasm", "Wheezing", "Shortness of Breath" ], "interventions": [ { "name": "Epinephrine Inhalation Aerosol, HFA", "type": "DRUG" }, { "name": "Epinephrine Inhalation Aerosol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amphastar Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "18 Years to 30 Years" }, "enrollment_count": 23, "start_date": "2010-08", "completion_date": "2011-01", "has_results": true, "last_update_posted_date": "2017-07-25", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 1, "location_summary": "Cypress, California", "locations": [ { "city": "Cypress", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01188577" }, { "nct_id": "NCT01024608", "title": "Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Seasonal Allergic Rhinitis", "Hay Fever" ], "interventions": [ { "name": "Beclomethasone dipropionate", "type": "DRUG" }, { "name": "Placebo Nasal Aerosol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 340, "start_date": "2009-12-31", "completion_date": "2010-02-28", "has_results": true, "last_update_posted_date": "2021-12-03", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 4, "location_summary": "Austin, Texas • New Braunfels, Texas • San Antonio, Texas + 1 more", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "New Braunfels", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" }, { "city": "Waco", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01024608" }, { "nct_id": "NCT01056159", "title": "A Cumulative Dose Study to Evaluate the Safety and Efficacy of Albuterol in a Dry Powder Inhaler and an HFA MDI (Hydrofluoroalkane Metered Dose Inhaler)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Albuterol dry powder inhaler", "type": "DRUG" }, { "name": "Albuterol HFA MDI (hydrofluoroalkane metered dose inhaler)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 47, "start_date": "2010-01", "completion_date": "2010-06", "has_results": false, "last_update_posted_date": "2022-02-02", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 9, "location_summary": "Los Angeles, California • Denver, Colorado • Lakewood, Colorado + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Lakewood", "state": "Colorado" }, { "city": "Normal", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01056159" }, { "nct_id": "NCT01133626", "title": "Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Adult and Adolescent Subjects With Perennial Allergic Rhinitis (PAR)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Perennial Allergic Rhinitis" ], "interventions": [ { "name": "Placebo Nasal Aerosol", "type": "DRUG" }, { "name": "Prednisone capsules", "type": "DRUG" }, { "name": "Placebo Prednisone Capsules", "type": "DRUG" }, { "name": "Beclomethasone dipropionate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "12 Years to 45 Years" }, "enrollment_count": 107, "start_date": "2010-06", "completion_date": "2010-09", "has_results": true, "last_update_posted_date": "2012-07-04", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 3, "location_summary": "North Dartmouth, Massachusetts • New Braunfels, Texas • San Antonio, Texas", "locations": [ { "city": "North Dartmouth", "state": "Massachusetts" }, { "city": "New Braunfels", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01133626" }, { "nct_id": "NCT02040779", "title": "A 12-week Safety and Efficacy Study of Beclomethasone Dipropionate (80 and 160 mcg/Day) Delivered Via Breath-Actuated Inhaler (BAI) in Patients >=12 Years Old With Persistent Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Persistent Asthma" ], "interventions": [ { "name": "Beclomethasone dipropionate breath-actuated inhaler", "type": "DRUG" }, { "name": "Placebo breath-actuated inhaler", "type": "DRUG" }, { "name": "albuterol/salbutamol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 273, "start_date": "2013-12-26", "completion_date": "2014-12-24", "has_results": true, "last_update_posted_date": "2021-11-09", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 47, "location_summary": "Huntington Beach, California • Mission Viejo, California • Orange, California + 41 more", "locations": [ { "city": "Huntington Beach", "state": "California" }, { "city": "Mission Viejo", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02040779" }, { "nct_id": "NCT00790023", "title": "Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Seasonal Allergic Rhinitis" ], "interventions": [ { "name": "80 mcg Ciclesonide", "type": "DRUG" }, { "name": "160 mcg Ciclesonide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sumitomo Pharma America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 707, "start_date": "2008-11", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2016-04-08", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 4, "location_summary": "Austin, Texas • Kerrville, Texas • New Braunfels, Texas + 1 more", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "Kerrville", "state": "Texas" }, { "city": "New Braunfels", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00790023" }, { "nct_id": "NCT02141854", "title": "Efficacy and Safety Study of FP MDPI Compared With FS MDPI in Adolescent and Adult Patients With Persistent Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "FS MDPI", "type": "DRUG" }, { "name": "Fp MDPI", "type": "DRUG" }, { "name": "Placebo MDPI", "type": "DRUG" }, { "name": "Albuterol/salmeterol HFA MDI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 882, "start_date": "2014-06", "completion_date": "2015-09", "has_results": true, "last_update_posted_date": "2021-11-09", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 85, "location_summary": "Birmingham, Alabama • Little Rock, Alaska • Phoenix, Arizona + 74 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Alaska" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Encinitas", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02141854" }, { "nct_id": "NCT05755932", "title": "Study to Assess Effect of Next-Generation Propellant MDI on Mucociliary Clearance Vs. HFA Propellant MDI in Healthy Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Mucociliary Clearance" ], "interventions": [ { "name": "HFO-1234ze(E)", "type": "DRUG" }, { "name": "HFA-134a", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 35, "start_date": "2023-06-14", "completion_date": "2024-07-22", "has_results": false, "last_update_posted_date": "2026-02-25", "last_synced_at": "2026-09-12T02:28:58.758Z", "location_count": 4, "location_summary": "Kansas City, Kansas • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Chapel Hill", "state": "North Carolina" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05755932" } ] }