{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HIV+and+substance+use+prevention",
    "query": {
      "intervention": "HIV and substance use prevention"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 95,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HIV+and+substance+use+prevention&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T17:21:03.167Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03855410",
      "title": "Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use",
        "Drug Use",
        "Adolescent Behavior",
        "Alcohol Use",
        "Sexual Risk Behavior"
      ],
      "interventions": [
        {
          "name": "S4E",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention-Matched Control Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 50,
      "start_date": "2016-10-27",
      "completion_date": "2017-08-31",
      "has_results": false,
      "last_update_posted_date": "2019-02-26",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Ypsilanti, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Ypsilanti",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03855410"
    },
    {
      "nct_id": "NCT03396367",
      "title": "Prevention and Risk: Treatment With a New Emphasis on Relationships",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adherence, Medication",
        "Risk Reduction",
        "Drug Use",
        "Sex, Anal",
        "HIV/AIDS"
      ],
      "interventions": [
        {
          "name": "PARTNER",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hunter College of City University of New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "MALE",
        "summary": "18 Years to 29 Years · Male only"
      },
      "enrollment_count": 196,
      "start_date": "2018-02-14",
      "completion_date": "2024-02-21",
      "has_results": true,
      "last_update_posted_date": "2025-10-29",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03396367"
    },
    {
      "nct_id": "NCT01113190",
      "title": "Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drug Abuse"
      ],
      "interventions": [
        {
          "name": "Computer-delivered Brief Intervention (CBI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intervener-delivered Brief Intervention (IBI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Adapted Motivational Enhancement Therapy (AMET)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care (EUC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 878,
      "start_date": "2011-02",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2016-04-07",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "Flint, Michigan",
      "locations": [
        {
          "city": "Flint",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01113190"
    },
    {
      "nct_id": "NCT01771237",
      "title": "HIV Prevention Among Vulnerable Male Youth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Homosexuality, Male",
        "HIV",
        "Substance-related Disorders",
        "Sexual Dysfunctions, Psychological"
      ],
      "interventions": [
        {
          "name": "MyPeeps Manualized Group Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Sexual Health Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "20 Years",
        "sex": "MALE",
        "summary": "16 Years to 20 Years · Male only"
      },
      "enrollment_count": 121,
      "start_date": "2007-07",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-27",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01771237"
    },
    {
      "nct_id": "NCT06880705",
      "title": "The Trans-Led Care Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Abuse",
        "Substance Addiction",
        "Substance Use Disorder (SUD)",
        "Substance Use (Drugs, Alcohol)",
        "Human Immunodeficiency Virus (HIV)"
      ],
      "interventions": [
        {
          "name": "The TLC Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Illinois Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2026-04-14",
      "completion_date": "2027-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06880705"
    },
    {
      "nct_id": "NCT06183502",
      "title": "HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sexually Transmitted Infections",
        "Gay",
        "Pre Exposure Prophylaxis"
      ],
      "interventions": [
        {
          "name": "Quantitative survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HIV and STI testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Qualitative Assessment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 675,
      "start_date": "2024-06-29",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-07-24",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Atlanta, Georgia • Chicago, Illinois",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06183502"
    },
    {
      "nct_id": "NCT01671501",
      "title": "Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Acquired Immunodeficiency Syndrome",
        "Alcoholism",
        "Alcoholic Intoxication",
        "Substance-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Email Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 614,
      "start_date": "2013-03",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2018-10-10",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01671501"
    },
    {
      "nct_id": "NCT06501781",
      "title": "Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections",
        "Substance Use"
      ],
      "interventions": [
        {
          "name": "Peer Activate-LAI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard of Care HIV treatment or prevention with LAI-PrEP/ART",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "88 Years",
        "sex": "ALL",
        "summary": "18 Years to 88 Years"
      },
      "enrollment_count": 186,
      "start_date": "2025-03-18",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-31",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06501781"
    },
    {
      "nct_id": "NCT07264582",
      "title": "HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex Trafficking",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Testing",
        "STI",
        "HCV",
        "Overdose, Drug"
      ],
      "interventions": [
        {
          "name": "Sex Trafficking Survivor-Developed Digital Crowdsourced Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 368,
      "start_date": "2026-10-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07264582"
    },
    {
      "nct_id": "NCT04680390",
      "title": "HIV Prevention Peer Navigation for Justice Involved Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections",
        "Stigma, Social"
      ],
      "interventions": [
        {
          "name": "Standard of care engagement practices",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 49 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2022-09-07",
      "completion_date": "2024-11-06",
      "has_results": true,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-09-26T17:21:03.167Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04680390"
    }
  ]
}