{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HLSE",
    "query": {
      "intervention": "HLSE"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T18:35:28.390Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02005445",
      "title": "Obstructive Sleep Apnea Treatment to Improve Cardiac Rehabilitation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Coronary Heart Disease"
      ],
      "interventions": [
        {
          "name": "CPAP",
          "type": "DEVICE"
        },
        {
          "name": "HLSE",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2014-10-01",
      "completion_date": "2018-06-29",
      "has_results": true,
      "last_update_posted_date": "2019-07-05",
      "last_synced_at": "2026-09-06T18:35:28.390Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02005445"
    },
    {
      "nct_id": "NCT01807897",
      "title": "Oxygen Versus PAP for Sleep Apnea in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Sleep Apnea Syndromes"
      ],
      "interventions": [
        {
          "name": "Continuous positive airway pressure",
          "type": "DEVICE"
        },
        {
          "name": "Nocturnal supplemental oxygen",
          "type": "DEVICE"
        },
        {
          "name": "Healthy Lifestyle and Sleep Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2014-06-23",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2023-01-25",
      "last_synced_at": "2026-09-06T18:35:28.390Z",
      "location_count": 2,
      "location_summary": "West Haven, Connecticut • Boston, Massachusetts",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01807897"
    },
    {
      "nct_id": "NCT01086800",
      "title": "Heart Biomarker Evaluation in Apnea Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Obstructive Sleep Apnea",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Healthy Lifestyles and Sleep Education plus PAP",
          "type": "OTHER"
        },
        {
          "name": "Healthy Lifestyles and Sleep Education plus Supplemental Oxygen",
          "type": "OTHER"
        },
        {
          "name": "Healthy Lifestyles and Sleep Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 318,
      "start_date": "2010-02",
      "completion_date": "2012-08",
      "has_results": false,
      "last_update_posted_date": "2013-02-25",
      "last_synced_at": "2026-09-06T18:35:28.390Z",
      "location_count": 4,
      "location_summary": "Baltimore, Maryland • Boston, Massachusetts • Cleveland, Ohio",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01086800"
    }
  ]
}