{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HP+129Xe+MRI&page=2", "query": { "intervention": "HP 129Xe MRI", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HP+129Xe+MRI&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-29T15:34:35.421Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05766384", "title": "Hyperpolarized 129Xe MRI Lung Health Cohort", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Healthy" ], "interventions": [ { "name": "Hyperpolarized Xe129", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "25 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "25 Years to 35 Years" }, "enrollment_count": 260, "start_date": "2023-11-30", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-05-01", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 6, "location_summary": "Chicago, Illinois • Iowa City, Iowa • Kansas City, Kansas + 2 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05766384" }, { "nct_id": "NCT02316379", "title": "Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Respiratory Disorders" ], "interventions": [ { "name": "Hyperpolarized 129 Xenon", "type": "DRUG" }, { "name": "MRI", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2015-02", "completion_date": "2032-12-24", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02316379" }, { "nct_id": "NCT04941573", "title": "Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Transplant Rejection" ], "interventions": [ { "name": "Hyperpolarized 129-Xenon (MagniXene) MRI of the lung", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Xemed LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 45, "start_date": "2021-01-19", "completion_date": "2025-09-04", "has_results": false, "last_update_posted_date": "2025-09-30", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04941573" }, { "nct_id": "NCT03367312", "title": "Assessing Response to Inhaled Prostacyclin With Hyperpolarized Xe MRI", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Vascular Disease" ], "interventions": [ { "name": "Hyperpolarized 129Xenon gas", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bastiaan Driehuys", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2018-03-29", "completion_date": "2022-11-01", "has_results": true, "last_update_posted_date": "2023-10-18", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03367312" }, { "nct_id": "NCT04035629", "title": "129Xe MRI in Pediatric Population With BPD", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Bronchopulmonary Dysplasia" ], "interventions": [ { "name": "MagniXene, hyperpolarized 129Xe MRI", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Xemed LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "1 Year", "sex": "ALL", "summary": "Up to 1 Year" }, "enrollment_count": 0, "start_date": "2026-08-01", "completion_date": "2031-12-31", "has_results": false, "last_update_posted_date": "2026-02-05", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04035629" }, { "nct_id": "NCT03002389", "title": "Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Anoro Ellipta", "type": "DRUG" }, { "name": "Arnuity Ellipta", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 95, "start_date": "2017-11-05", "completion_date": "2028-01-31", "has_results": false, "last_update_posted_date": "2024-11-18", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Keswick, Virginia", "locations": [ { "city": "Keswick", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03002389" }, { "nct_id": "NCT03482960", "title": "Comparison of 129Xe MRI With 19F MRI in CF Lung Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "Hyperpolarized Xenon gas", "type": "DRUG" }, { "name": "PFP", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2018-05-29", "completion_date": "2019-04-10", "has_results": false, "last_update_posted_date": "2021-01-25", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03482960" }, { "nct_id": "NCT04467957", "title": "Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "Initiation of CFTR Modulator", "type": "DRUG" }, { "name": "Hyperpolarized Xenon 129", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "6 Years to 21 Years" }, "enrollment_count": 26, "start_date": "2020-11-15", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-01-28", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04467957" }, { "nct_id": "NCT03078192", "title": "Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Vascular Disease" ], "interventions": [ { "name": "GE-141, Hyperpolarized 129Xenon gas", "type": "DRUG" }, { "name": "MRI", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Bastiaan Driehuys", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2017-05-03", "completion_date": "2020-10-22", "has_results": true, "last_update_posted_date": "2022-02-22", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03078192" }, { "nct_id": "NCT07046910", "title": "Developing Hyperpolarized Gas MRI Signatures to Detect and Manage Acute Cellular Rejection", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Transplant Rejection" ], "interventions": [ { "name": "Sub study (Active): Two Lung MRI study with two navigational Bronchoscopy", "type": "DIAGNOSTIC_TEST" }, { "name": "Hyperpolarized Xenon129", "type": "DRUG" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "DRUG" ], "sponsor": "University of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 60, "start_date": "2019-04-01", "completion_date": "2029-03-31", "has_results": false, "last_update_posted_date": "2026-03-17", "last_synced_at": "2026-09-29T15:34:35.421Z", "location_count": 1, "location_summary": "Charlottesville, Virginia", "locations": [ { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07046910" } ] }