{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HRQOL+questionnaire&page=2",
    "query": {
      "intervention": "HRQOL questionnaire",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HRQOL+questionnaire&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T11:32:48.335Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01959958",
      "title": "Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Questionnaire/Interview",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 250,
      "start_date": "2013-10",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-11",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01959958"
    },
    {
      "nct_id": "NCT04447222",
      "title": "Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19 Infection",
        "Malignant Solid Neoplasm"
      ],
      "interventions": [
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1242,
      "start_date": "2020-05-12",
      "completion_date": "2028-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04447222"
    },
    {
      "nct_id": "NCT01838265",
      "title": "Trial of Prostate Cancer Patients Undergoing Active Surveillance With or Without MRI-Guided Management",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prostate Cancer",
        "Prostate Adenocarcinoma"
      ],
      "interventions": [
        {
          "name": "Transrectal Ultrasound-Guided Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "MRI Ultrasound Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Expanded Prostate Cancer index Composite Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Short-Form 12 of Health Related Quality of Life Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Memorial Anxiety Scale for Prostate Cancer",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Plasma/Serum Sample for biomarkers",
          "type": "PROCEDURE"
        },
        {
          "name": "Urine Sample for Biomarkers",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood Tests for Blood Urea Nitrogen and Creatinine",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood Test for Serum PSA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "35 Years to 75 Years · Male only"
      },
      "enrollment_count": 0,
      "start_date": "2012-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-12-08",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01838265"
    },
    {
      "nct_id": "NCT02562027",
      "title": "SBRT (Stereotactic Body Radiation Therapy) vs. Surgery in High Risk Patients With Early Stage Lung Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Carcinoma, Non-Small-Cell-Lung",
        "Non-Small Cell Lung Cancer",
        "Nonsmall Cell Lung Cancer"
      ],
      "interventions": [
        {
          "name": "European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30",
          "type": "BEHAVIORAL"
        },
        {
          "name": "European Organization for Research and Treatment of Cancer Quality of Life Questionnaire LC-13",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Medical Research Council",
          "type": "BEHAVIORAL"
        },
        {
          "name": "EQ-5D",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Center for Epidemiological Studies Depression Scale",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medical Outcomes Study Social Support Survey",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 217,
      "start_date": "2015-09-11",
      "completion_date": "2020-11-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02562027"
    },
    {
      "nct_id": "NCT06982066",
      "title": "Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Cancer",
        "Adolescent and Young Adult Cancer"
      ],
      "interventions": [
        {
          "name": "ReSPECT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Connecticut Children's Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "15 Years to 25 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-02-10",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06982066"
    },
    {
      "nct_id": "NCT03459352",
      "title": "Digital Symptom Tracking, Patient Engagement and Quality of Life in GI Oncology Clinic Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "ePRO",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2018-06-18",
      "completion_date": "2020-04-04",
      "has_results": false,
      "last_update_posted_date": "2020-08-26",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03459352"
    },
    {
      "nct_id": "NCT06123988",
      "title": "Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HER2-positive Breast Cancer",
        "Advanced Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Prolonged Overnight Fasting",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate-Intensity Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "General Health Education Sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 260,
      "start_date": "2024-09-09",
      "completion_date": "2029-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Miami, Florida • Boston, Massachusetts",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06123988"
    },
    {
      "nct_id": "NCT00493259",
      "title": "Health Related QOL, Depression and Lifestyle Changes in Insulin Resistant Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Insulin Resistance",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Health-Related Quality of Life instrument",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Depression Scale for Children (CES-DC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "11 Years to 17 Years"
      },
      "enrollment_count": 78,
      "start_date": "2007-06",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2021-01-06",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00493259"
    },
    {
      "nct_id": "NCT02119390",
      "title": "Medication Adherence in Human Immunodeficiency Virus (HIV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus"
      ],
      "interventions": [
        {
          "name": "Staff-delivered intervention sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Demographic Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "13 Years to 24 Years"
      },
      "enrollment_count": 33,
      "start_date": "2014-04",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2016-08-02",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02119390"
    },
    {
      "nct_id": "NCT07619040",
      "title": "Patient-Reported Probiotic Use During Periodontal Therapy in Periodontitis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontitis",
        "Probiotic",
        "Oral Hygiene, Oral Health",
        "Periodontal Therapy"
      ],
      "interventions": [
        {
          "name": "non surgical periodontal therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medipol University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 130,
      "start_date": "2025-12-20",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-09-26T11:32:48.335Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07619040"
    }
  ]
}