{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HVLA+chiropractic+manipulation",
    "query": {
      "intervention": "HVLA chiropractic manipulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=HVLA+chiropractic+manipulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T19:42:36.988Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06153290",
      "title": "Patient Perceptions Following a Single Session of Simulated or Genuine HVLA Manual Chiropractic Adjustments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subluxation"
      ],
      "interventions": [
        {
          "name": "Chiropractic adjustment",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Life University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-01-04",
      "completion_date": "2024-08-26",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Marietta, Georgia",
      "locations": [
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06153290"
    },
    {
      "nct_id": "NCT06931600",
      "title": "Simulated vs Genuine Manual Chiropractic Adjustments",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subluxation"
      ],
      "interventions": [
        {
          "name": "Sham adjustment",
          "type": "PROCEDURE"
        },
        {
          "name": "Chiropractic adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Life University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-05-05",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Marietta, Georgia",
      "locations": [
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06931600"
    },
    {
      "nct_id": "NCT02168153",
      "title": "Assessment of Chiropractic Treatment Using Reaction and Response Times in Members of the Special Operation Forces (ACT2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physiological Measurements of Response and Reaction Times"
      ],
      "interventions": [
        {
          "name": "Chiropractic Manipulative Therapy",
          "type": "OTHER"
        },
        {
          "name": "Wait-list",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAND",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2014-08",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2019-04-19",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Fort Campbell North, Kentucky",
      "locations": [
        {
          "city": "Fort Campbell North",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02168153"
    },
    {
      "nct_id": "NCT01842737",
      "title": "PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Massage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 8,
      "start_date": "2013-04",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01842737"
    },
    {
      "nct_id": "NCT05401903",
      "title": "Relationship Between Chiropractic Care and Autonomic Nervous System Regulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chiropractic Maintenance Care and Heart Rate Variability"
      ],
      "interventions": [
        {
          "name": "Chiropractic Maintenance Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northeast College of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-06-01",
      "completion_date": "2023-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Seneca Falls, New York",
      "locations": [
        {
          "city": "Seneca Falls",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05401903"
    },
    {
      "nct_id": "NCT00602901",
      "title": "Elderly Back Pain: Comparing Chiropractic to Medical Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Subacute Low Back Pain",
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        },
        {
          "name": "LVVA-SM",
          "type": "OTHER"
        },
        {
          "name": "Usual medical care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2004-07",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2017-04-06",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 2,
      "location_summary": "Davenport, Iowa • Iowa City, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00602901"
    },
    {
      "nct_id": "NCT03916705",
      "title": "Thoraco-Lumbar Fascia Mobility",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "High Velocity Low amplitude spinal manipulation (HVLA-SM)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2019-09-09",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916705"
    },
    {
      "nct_id": "NCT05310565",
      "title": "The Effects of Chiropractic in Adults With Colon Cancer",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colon Cancer Stage III",
        "Colon Cancer Stage IV"
      ],
      "interventions": [
        {
          "name": "HVLA cervical chiropractic adjustments",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Life University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-01-01",
      "completion_date": "2025-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-03",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05310565"
    },
    {
      "nct_id": "NCT00524654",
      "title": "The Effects of Cervical Spine Manipulation On Postural Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Posture"
      ],
      "interventions": [
        {
          "name": "HVLA chiropractic manipulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Logan College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 30,
      "start_date": "2007-08",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2008-10-17",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Chesterfield, Missouri",
      "locations": [
        {
          "city": "Chesterfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00524654"
    },
    {
      "nct_id": "NCT00830596",
      "title": "Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        },
        {
          "name": "LVVA-SM",
          "type": "OTHER"
        },
        {
          "name": "Sham Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 221,
      "start_date": "2007-07",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-09-23T19:42:36.988Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830596"
    }
  ]
}