{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Half-normal+saline&page=2",
    "query": {
      "intervention": "Half-normal saline",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Half-normal+saline&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T06:02:35.758Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01670565",
      "title": "Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Systemic Sclerosis"
      ],
      "interventions": [
        {
          "name": "Belimumab",
          "type": "DRUG"
        },
        {
          "name": "Mycophenolate Mofetil",
          "type": "DRUG"
        },
        {
          "name": "Placebo Infusion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2012-08",
      "completion_date": "2016-02",
      "has_results": true,
      "last_update_posted_date": "2022-05-24",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01670565"
    },
    {
      "nct_id": "NCT01522040",
      "title": "Pilot Study of Magnesium Infusions in Pediatric Asthma",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Magnesium Sulfate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "2 Years to 20 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-01",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01522040"
    },
    {
      "nct_id": "NCT05283850",
      "title": "Surviving PEA in Roanoke (SPEAR) Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cardiac Arrest",
        "Pulseless Electrical Activity"
      ],
      "interventions": [
        {
          "name": "High Calcium, Low Sodium (HCLS) Crystalloid Therapy",
          "type": "DRUG"
        },
        {
          "name": "High Calcium, High Sodium (HCHS) Crystalloid Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Carol Bernier",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 342,
      "start_date": "2022-02-16",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2022-03-17",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05283850"
    },
    {
      "nct_id": "NCT01941745",
      "title": "Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome in Premature Infant",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Half normal saline",
          "type": "DRUG"
        },
        {
          "name": "Low Dose rhCC10",
          "type": "DRUG"
        },
        {
          "name": "High dose rhCC10",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 29 Weeks"
      },
      "enrollment_count": 88,
      "start_date": "2013-10",
      "completion_date": "2017-08-25",
      "has_results": true,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Springfield, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01941745"
    },
    {
      "nct_id": "NCT06953635",
      "title": "Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hernia, Ventral",
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "Quadratus Lumborum (QL) Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Tennessee Graduate School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-06-01",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-05-01",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06953635"
    },
    {
      "nct_id": "NCT02772276",
      "title": "Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "MB-102-- single dose of 4 µmol/kg",
          "type": "DRUG"
        },
        {
          "name": "MB-102-- single dose of 130 mg",
          "type": "DRUG"
        },
        {
          "name": "MB-102-single dose of 130 mg or 2 doses of 130 mg 12 hours apart",
          "type": "DRUG"
        },
        {
          "name": "MB-102-- two doses of 130 mg 24 hours apart",
          "type": "DRUG"
        },
        {
          "name": "Iohexol",
          "type": "DRUG"
        },
        {
          "name": "QuantumLeap",
          "type": "DEVICE"
        },
        {
          "name": "Radiance",
          "type": "DEVICE"
        },
        {
          "name": "Brilliance (1 or 2 sensors)",
          "type": "DEVICE"
        },
        {
          "name": "Brilliance (2-part sensor)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "MediBeacon",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 234,
      "start_date": "2016-05-11",
      "completion_date": "2021-08-04",
      "has_results": true,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 3,
      "location_summary": "Edgewater, Florida • Orlando, Florida • St Louis, Missouri",
      "locations": [
        {
          "city": "Edgewater",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02772276"
    },
    {
      "nct_id": "NCT00005777",
      "title": "Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Respiratory Distress Syndrome",
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature"
      ],
      "interventions": [
        {
          "name": "Minimal mechanical ventilation management",
          "type": "PROCEDURE"
        },
        {
          "name": "Routine mechanical ventilation management",
          "type": "PROCEDURE"
        },
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Minutes",
        "maximum_age": "10 Days",
        "sex": "ALL",
        "summary": "5 Minutes to 10 Days"
      },
      "enrollment_count": 220,
      "start_date": "1998-02",
      "completion_date": "2002-09",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005777"
    },
    {
      "nct_id": "NCT05626621",
      "title": "Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic Rhinitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Rhinitis"
      ],
      "interventions": [
        {
          "name": "Azelastine (137 mcg/spray) Nasal Spray and Mometasone (50 mcg/spray) Nasal Spray",
          "type": "DRUG"
        },
        {
          "name": "Mometasone Nasal Irrigation (1 mg capsule)",
          "type": "DRUG"
        },
        {
          "name": "Mometasone (1 mg) and Azelastine (1 mg) Nasal Irrigation",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2022-11-23",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2023-07-28",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 1,
      "location_summary": "Evanston, Illinois",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05626621"
    },
    {
      "nct_id": "NCT00414466",
      "title": "A Safety and Effectiveness Study of Intraspinal Gabapentin (MDT2004) for the Treatment of Chronic Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Intractable Pain"
      ],
      "interventions": [
        {
          "name": "Intraspinal Gabapentin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "MedtronicNeuro",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 254,
      "start_date": "2006-12",
      "completion_date": "2010-08",
      "has_results": true,
      "last_update_posted_date": "2013-08-23",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 14,
      "location_summary": "Little Rock, Arkansas • Napa, California • Sarasota, Florida + 11 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Napa",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00414466"
    },
    {
      "nct_id": "NCT05777174",
      "title": "Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Kidney Diseases",
        "Kidney Injury",
        "Kidney Failure"
      ],
      "interventions": [
        {
          "name": "MB-102",
          "type": "DRUG"
        },
        {
          "name": "MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "MediBeacon",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 149,
      "start_date": "2023-03-20",
      "completion_date": "2024-04-15",
      "has_results": true,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-09-23T06:02:35.758Z",
      "location_count": 5,
      "location_summary": "Chicago, Illinois • Columbus, Ohio • Austin, Texas + 1 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05777174"
    }
  ]
}