{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Headache+pain+score",
    "query": {
      "intervention": "Headache pain score"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Headache+pain+score&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T10:43:24.782Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01629329",
      "title": "Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Migraine Headaches"
      ],
      "interventions": [
        {
          "name": "Aspirin, Acetaminophen, Caffeine pills",
          "type": "DRUG"
        },
        {
          "name": "Prochlorperazine 10mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Albert Einstein Healthcare Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 93,
      "start_date": "2010-11",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01629329"
    },
    {
      "nct_id": "NCT03576820",
      "title": "Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York City Health and Hospitals Corporation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "10 Years to 20 Years"
      },
      "enrollment_count": 50,
      "start_date": "2018-10-15",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2021-01-05",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03576820"
    },
    {
      "nct_id": "NCT05926024",
      "title": "Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Exercise Recall Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Behavior Questionnaire (HBQ)30 Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Cancer Therapy-General (FACT-G) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS Cognitive Function (Short Form 8a)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Functional Assessment of Cancer-Gynecology Oncology Group-Neurotoxicity (FACT/GOG-NTX-12)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes FACT-Endocrine Symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Penn Arthralgia Aging Survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PRO-CTCAE (patient-reported CTCAE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "p16 tumor suppressor gene",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 253,
      "start_date": "2023-01-06",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926024"
    },
    {
      "nct_id": "NCT03058003",
      "title": "Correlation Between Central Sensitization Inventory and Posturographic Data",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Central Nervous System Sensitization"
      ],
      "interventions": [
        {
          "name": "Posturography Evaluation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Central Sensitization Inventory",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Caps Research Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 180,
      "start_date": "2016-05",
      "completion_date": "2021-04",
      "has_results": false,
      "last_update_posted_date": "2021-08-04",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Marietta, Georgia",
      "locations": [
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03058003"
    },
    {
      "nct_id": "NCT04732338",
      "title": "The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Headache",
        "Post-Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hackensack Meridian Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2017-08-01",
      "completion_date": "2020-02-11",
      "has_results": true,
      "last_update_posted_date": "2021-05-25",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Edison, New Jersey",
      "locations": [
        {
          "city": "Edison",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04732338"
    },
    {
      "nct_id": "NCT05738213",
      "title": "Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Thermal stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pressure stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pain ratings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pressure pain thresholds (PPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioned pain modulation (CPM) response",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PedMIDAS (Pediatric Migraine Disability Assessment)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hormonal assessment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Pubertal status",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "11 Years to 15 Years"
      },
      "enrollment_count": 100,
      "start_date": "2023-01-10",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05738213"
    },
    {
      "nct_id": "NCT03150524",
      "title": "RCVS: The Rational Approach to Diagnosis and Treatment",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Reversible Cerebral Vasoconstriction Syndrome"
      ],
      "interventions": [
        {
          "name": "TCD- cerebral blood flow velocities",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Headache pain score",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neurological examination",
          "type": "OTHER"
        },
        {
          "name": "Repeat Neuroimaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Nimodipine",
          "type": "DRUG"
        },
        {
          "name": "Verapamil ER",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-07-01",
      "completion_date": "2019-05-31",
      "has_results": false,
      "last_update_posted_date": "2019-09-18",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03150524"
    },
    {
      "nct_id": "NCT02123615",
      "title": "ASIS for GAMMAGARD in Primary Immunodeficiency",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Primary Immunodeficiency"
      ],
      "interventions": [
        {
          "name": "Gadolinium For abdomen",
          "type": "DRUG"
        },
        {
          "name": "Gadolinium For lower back",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subcutaneously at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subcutaneously at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subcutaneously at Week 36",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subdermally at Week 36",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subdermally at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Gammagard subdermally at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subcutaneously at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subcutaneously at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subcutaneously at Week 36",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subdermally at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subdermally at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Gammagard subdermally at Week 36",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ASIS Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-01",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-24",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Westminster, California",
      "locations": [
        {
          "city": "Westminster",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02123615"
    },
    {
      "nct_id": "NCT02074150",
      "title": "ASIS for Botox in Upper Limb Spasticity",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Upper Limb Spasticity Unilaterally in Adults With History of Stroke",
        "Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors."
      ],
      "interventions": [
        {
          "name": "Gadolinium",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 12,",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox intramuscularly",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox subdermally",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "li nguyen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-01",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-24",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Westminster, California",
      "locations": [
        {
          "city": "Westminster",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02074150"
    },
    {
      "nct_id": "NCT02074293",
      "title": "ASIS for Botox in Cervical Dystonia",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cervical Dystonia Adults ,",
        "Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus."
      ],
      "interventions": [
        {
          "name": "Gadolinium",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox intramuscularly",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox subdermally",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "li nguyen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-01",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-24",
      "last_synced_at": "2026-09-23T10:43:24.782Z",
      "location_count": 1,
      "location_summary": "Westminster, California",
      "locations": [
        {
          "city": "Westminster",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02074293"
    }
  ]
}