{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heart+Rate+Variability&page=2",
    "query": {
      "intervention": "Heart Rate Variability",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heart+Rate+Variability&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T10:43:13.766Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05224050",
      "title": "Heart Rate Variability Biofeedback for Smoking Cessation Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Cognitive-Behavioral Smoking Cessation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 28,
      "start_date": "2021-11-29",
      "completion_date": "2023-06-15",
      "has_results": true,
      "last_update_posted_date": "2024-05-01",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05224050"
    },
    {
      "nct_id": "NCT06526585",
      "title": "Stress Management Program",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Cyclic Sighing Breathing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Box Breathing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hypnosis",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Audiobook",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2025-03-12",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06526585"
    },
    {
      "nct_id": "NCT04275830",
      "title": "The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hematopoietic Stem Cell Transplantation",
        "Bone Marrow Transplant",
        "Heart Rate Variability",
        "Autonomic Nervous System",
        "Stress",
        "Mood",
        "Psychological Distress",
        "Emotion Regulation",
        "Communication Research",
        "Narrative"
      ],
      "interventions": [
        {
          "name": "Baseline Surveys",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability waitlist and Digital storytelling Control intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2020-02-04",
      "completion_date": "2022-02-04",
      "has_results": false,
      "last_update_posted_date": "2022-05-23",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04275830"
    },
    {
      "nct_id": "NCT06093100",
      "title": "Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Duchenne Muscular Dystrophy"
      ],
      "interventions": [
        {
          "name": "wearable technology",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "10 Years and older · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2024-07-10",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-06",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06093100"
    },
    {
      "nct_id": "NCT05374798",
      "title": "Wearable Technology and Alcohol-Facilitated Intimate Partner Violence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Abuse",
        "IPV",
        "Couples"
      ],
      "interventions": [
        {
          "name": "Heart Rate Variability-Biofeedback (HRV-B) via Smartwatch Device Intervention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 92,
      "start_date": "2023-01-27",
      "completion_date": "2024-05-28",
      "has_results": true,
      "last_update_posted_date": "2025-07-14",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05374798"
    },
    {
      "nct_id": "NCT03253952",
      "title": "A Study of Autonomic Dynamic Dysfunction to Predict Infections After Spinal Cord Injury.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma, Spinal Cord",
        "SPINAL Fracture"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2017-09-29",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03253952"
    },
    {
      "nct_id": "NCT05994664",
      "title": "Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Heartmath Intervention",
          "type": "OTHER"
        },
        {
          "name": "Control Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "12 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-04-01",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05994664"
    },
    {
      "nct_id": "NCT01237886",
      "title": "Weaning And Variability Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mechanically Ventilated Patients",
        "Extubation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ottawa Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 660,
      "start_date": "2009-11",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2017-07-07",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 7,
      "location_summary": "Ann Arbor, Michigan • Billings, Montana • Lebanon, New Hampshire + 4 more",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Billings",
          "state": "Montana"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01237886"
    },
    {
      "nct_id": "NCT03235466",
      "title": "A Prospective Trial of Behavioral Therapy for Chronic Cough",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cough"
      ],
      "interventions": [
        {
          "name": "Voice Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Voice Therapy and Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-02-01",
      "completion_date": "2021-12-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-04",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03235466"
    },
    {
      "nct_id": "NCT00933881",
      "title": "Gestational Diabetes and Sleep-Disordered Breathing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gestational Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Determining a change in heart rate variability post delivery of the baby",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 32,
      "start_date": "2008-11",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-09-03T10:43:13.766Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00933881"
    }
  ]
}