{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heart+to+Heart",
    "query": {
      "intervention": "Heart to Heart"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6487,
    "total_pages": 649,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heart+to+Heart&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T01:07:22.453Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00847132",
      "title": "A Collaborative Care Program to Improve Depression Treatment in Cardiac Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Congestive Heart Failure",
        "Arrhythmia",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Collaborative Care Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2007-07",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2017-03-31",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00847132"
    },
    {
      "nct_id": "NCT04901793",
      "title": "Efficacy of Virtual Reality in Pain Reduction in Orthopedic Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthopedic Disorder",
        "Fractures, Bone"
      ],
      "interventions": [
        {
          "name": "Virtual Reality Headset and handheld remote control.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ochsner Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "5 Years to 18 Years"
      },
      "enrollment_count": 95,
      "start_date": "2019-07-01",
      "completion_date": "2020-03-16",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Jefferson, Louisiana",
      "locations": [
        {
          "city": "Jefferson",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901793"
    },
    {
      "nct_id": "NCT00401687",
      "title": "DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ventricular Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lantheus Medical Imaging",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 131,
      "start_date": "2006-07",
      "completion_date": "2008-04",
      "has_results": false,
      "last_update_posted_date": "2011-05-20",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 10,
      "location_summary": "Tucson, Arizona • Chicago, Illinois • Washington DC, Maryland + 7 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Washington DC",
          "state": "Maryland"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00401687"
    },
    {
      "nct_id": "NCT03915587",
      "title": "Bedside Resources to Gauge Intravascular Volume Status",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypovolemia",
        "Craniosynostoses"
      ],
      "interventions": [
        {
          "name": "CardioQ-EDM and CipherOx-CRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "3 Months to 2 Years"
      },
      "enrollment_count": 23,
      "start_date": "2019-04-08",
      "completion_date": "2020-03-12",
      "has_results": true,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03915587"
    },
    {
      "nct_id": "NCT00205387",
      "title": "Cardiac Elastography to Determine Strain and Strain Rates in the Heart",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "cardiac elastography and echocardiography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 100,
      "start_date": "2005-11",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-08-29",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00205387"
    },
    {
      "nct_id": "NCT00846378",
      "title": "Minimizing Reperfusion Injury in Patients With Acute Myocardial Infarction",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Acute Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "Post conditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Usual Care for STEMI",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2008-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-02-03",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00846378"
    },
    {
      "nct_id": "NCT06149143",
      "title": "Cardiac Performance System Data Collection Study - Minnesota",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Disease"
      ],
      "interventions": [
        {
          "name": "Cardiac Performance System (NSR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sensydia Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-10-03",
      "completion_date": "2024-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06149143"
    },
    {
      "nct_id": "NCT06306768",
      "title": "Remote Therapeutic Monitoring Exercise Tracking",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Activity Monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 200,
      "start_date": "2024-04-01",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06306768"
    },
    {
      "nct_id": "NCT03241485",
      "title": "Trial Comparing Intrathecal Morphine With Placebo In Patients Undergoing Robotic Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Intrathecal morphine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 79,
      "start_date": "2018-06-19",
      "completion_date": "2020-09-01",
      "has_results": true,
      "last_update_posted_date": "2021-11-23",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241485"
    },
    {
      "nct_id": "NCT03525743",
      "title": "Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypotension"
      ],
      "interventions": [
        {
          "name": "NICOM (Non invasive cardiac output monitor)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2018-06-27",
      "completion_date": "2019-03-29",
      "has_results": false,
      "last_update_posted_date": "2022-09-01",
      "last_synced_at": "2026-09-04T01:07:22.453Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • New York, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03525743"
    }
  ]
}