{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heat+application",
    "query": {
      "intervention": "Heat application"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 132,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Heat+application&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T12:40:24.217Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07397078",
      "title": "Clinical Accuracy Validation of the Moni-Patch Temperature Monitoring Patch System",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Body Temperature",
        "Febrile"
      ],
      "interventions": [
        {
          "name": "Moni-Patch Temperature Monitoring Patch System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Murata Vios, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2026-01-21",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "Woodbury, Minnesota",
      "locations": [
        {
          "city": "Woodbury",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07397078"
    },
    {
      "nct_id": "NCT02429557",
      "title": "Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Orthostatic Hypotension",
        "Pure Autonomic Failure",
        "Multiple System Atrophy",
        "Autonomic Failure"
      ],
      "interventions": [
        {
          "name": "Abdominal compression",
          "type": "OTHER"
        },
        {
          "name": "Sham abdominal compression",
          "type": "OTHER"
        },
        {
          "name": "Placebo pill",
          "type": "DRUG"
        },
        {
          "name": "midodrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 21,
      "start_date": "2015-04",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02429557"
    },
    {
      "nct_id": "NCT06617494",
      "title": "Endogenous Pain Inhibition Deficiency in Chronic TMD Pain",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Temporomandibular Disorders (TMD)"
      ],
      "interventions": [
        {
          "name": "Pain modulation testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-09-16",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06617494"
    },
    {
      "nct_id": "NCT07478926",
      "title": "Flow Detection in Open and Closed Shunt Valve Periods",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hydrocephalus"
      ],
      "interventions": [
        {
          "name": "Rhaeos Shunt Monitoring System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rhaeos, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 55,
      "start_date": "2026-01-27",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "Peoria, Illinois",
      "locations": [
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07478926"
    },
    {
      "nct_id": "NCT02034331",
      "title": "IR and Microvascular Blood Flow in SCI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Insulin iontophoresis",
          "type": "DRUG"
        },
        {
          "name": "Placebo Iontophoresis",
          "type": "DRUG"
        },
        {
          "name": "Acetylcholine Iontophoresis",
          "type": "DRUG"
        },
        {
          "name": "Heat application",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "20 Years to 69 Years"
      },
      "enrollment_count": 68,
      "start_date": "2012-12",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-03-07",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02034331"
    },
    {
      "nct_id": "NCT05335161",
      "title": "A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "Home-based leg heat therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2023-05-30",
      "completion_date": "2024-02-07",
      "has_results": true,
      "last_update_posted_date": "2025-08-15",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05335161"
    },
    {
      "nct_id": "NCT06361381",
      "title": "The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous Electrical Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-04-01",
      "completion_date": "2024-10-20",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06361381"
    },
    {
      "nct_id": "NCT05145595",
      "title": "Pain Sensitivity During Puberty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Thermal Sensory Analyzer",
          "type": "DEVICE"
        },
        {
          "name": "Pressure Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Mechanical Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pain Ratings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Thermal pain thresholds",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pressure pain thresholds (PPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mechanical temporal summation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioned pain modulation (CPM) efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Offset analgesia efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cold pain tolerance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "9 Years to 16 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-09-20",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05145595"
    },
    {
      "nct_id": "NCT06542276",
      "title": "Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "MGD-Meibomian Gland Dysfunction"
      ],
      "interventions": [
        {
          "name": "Thermal Vectored Pulsation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dunes Eye Consultants",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-01",
      "completion_date": "2024-09-01",
      "has_results": false,
      "last_update_posted_date": "2024-08-12",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 1,
      "location_summary": "Dakota Dunes, South Dakota",
      "locations": [
        {
          "city": "Dakota Dunes",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06542276"
    },
    {
      "nct_id": "NCT01807585",
      "title": "VenaSeal Sapheon Closure System Pivotal Study (VeClose)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Great Saphenous Vein (GSV) With Venous Reflux Disease"
      ],
      "interventions": [
        {
          "name": "VenaSeal SCS",
          "type": "DEVICE"
        },
        {
          "name": "ClosureFast Radiofrequency Ablation (RFA)",
          "type": "DEVICE"
        },
        {
          "name": "Roll-in (VenaSeal SCS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Endovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 242,
      "start_date": "2013-03",
      "completion_date": "2017-04-10",
      "has_results": true,
      "last_update_posted_date": "2018-06-26",
      "last_synced_at": "2026-09-05T12:40:24.217Z",
      "location_count": 10,
      "location_summary": "Scottsdale, Arizona • San Diego, California • Greenwood Village, Colorado + 7 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Oakbrook Terrace",
          "state": "Illinois"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01807585"
    }
  ]
}