{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Activity&page=50",
    "query": {
      "intervention": "High Activity",
      "page": 50
    },
    "page_size": 10
  },
  "pagination": {
    "page": 50,
    "page_size": 10,
    "total_count": 2754,
    "total_pages": 276,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Activity&page=51&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Activity&page=49&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-05T14:59:37.245Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03777722",
      "title": "Light and the Effect on Metabolic Syndrome and Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Tailored Lighting Intervention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2018-11-19",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 3,
      "location_summary": "New Brunswick, New Jersey • Albany, New York • New York, New York",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03777722"
    },
    {
      "nct_id": "NCT00109746",
      "title": "Use of a Nutritional Supplement to Treat Diabetic Symptoms in HIV-Infected Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Insulin Resistance",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "chromium picolinate",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2005-11",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2016-03-23",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00109746"
    },
    {
      "nct_id": "NCT01362205",
      "title": "Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Alcohol Withdrawal Delirium",
        "Alcohol Withdrawal Associated Autonomic Hyperactivity",
        "Alcohol Withdrawal Hallucinosis",
        "Alcohol Withdrawal-Induced Delirium Tremens"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 49,
      "start_date": "2012-03",
      "completion_date": "2016-09",
      "has_results": true,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 7,
      "location_summary": "Colorado Springs, Colorado • Denver, Colorado • Lakewood, Colorado + 2 more",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Lakewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01362205"
    },
    {
      "nct_id": "NCT01971567",
      "title": "High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "HIRREM",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2013-10",
      "completion_date": "2017-02-06",
      "has_results": true,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01971567"
    },
    {
      "nct_id": "NCT00995007",
      "title": "A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glioblastoma Multiforme",
        "Gliosarcoma",
        "Anaplastic Astrocytoma",
        "Anaplastic Oligodendroglioma",
        "Anaplastic Mixed Oligoastrocytoma"
      ],
      "interventions": [
        {
          "name": "ZD6474 (Vandetanib)",
          "type": "DRUG"
        },
        {
          "name": "Carboplatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 112,
      "start_date": "2009-09",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2016-03-29",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00995007"
    },
    {
      "nct_id": "NCT03721900",
      "title": "Ketamine for Major Depressive Disorder",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "SHX-001 Active low dose",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "SHX-001 Active High dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shenox Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 14,
      "start_date": "2018-12-28",
      "completion_date": "2019-06-06",
      "has_results": false,
      "last_update_posted_date": "2019-04-25",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 3,
      "location_summary": "Gaithersburg, Maryland • Boston, Massachusetts • Dayton, Ohio",
      "locations": [
        {
          "city": "Gaithersburg",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03721900"
    },
    {
      "nct_id": "NCT01003730",
      "title": "The Effects of Different Ventilator Strategies on Inflammation and Injury in Normal Lungs",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Ventilator settings",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 1,
      "start_date": "2009-03",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2015-05-05",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01003730"
    },
    {
      "nct_id": "NCT05700630",
      "title": "Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV-1-infection",
        "ART",
        "Cd4+ Lymphocyte Deficiency",
        "Lymphoid Tissue; Infection",
        "Interleukin"
      ],
      "interventions": [
        {
          "name": "FT538",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Vorinostat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2024-07-15",
      "completion_date": "2024-08-21",
      "has_results": false,
      "last_update_posted_date": "2024-02-26",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05700630"
    },
    {
      "nct_id": "NCT01571128",
      "title": "Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Adolescent Behavior",
        "Gender"
      ],
      "interventions": [
        {
          "name": "Male-Specific Intervention Package",
          "type": "OTHER"
        },
        {
          "name": "Female-Specific Intervention Package",
          "type": "OTHER"
        },
        {
          "name": "Pre-Exposure Prophylaxis (Females)",
          "type": "DRUG"
        },
        {
          "name": "Cash Transfer Cohort (Females)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "New York University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "15 Years to 24 Years"
      },
      "enrollment_count": 1215,
      "start_date": "2014-11",
      "completion_date": "2016-03-23",
      "has_results": false,
      "last_update_posted_date": "2022-02-18",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01571128"
    },
    {
      "nct_id": "NCT02221934",
      "title": "Electrical Nerve Block for Amputation Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Amputation Pain",
        "Phantom Limb Pain",
        "Residual Limb Pain",
        "Stump Pain"
      ],
      "interventions": [
        {
          "name": "Altius",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Neuros Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 607,
      "start_date": "2014-10-09",
      "completion_date": "2025-09-01",
      "has_results": true,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-11-05T14:59:37.245Z",
      "location_count": 22,
      "location_summary": "Scottsdale, Arizona • Little Rock, Arkansas • Denver, Colorado + 18 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02221934"
    }
  ]
}