{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+CPAP+Wean",
    "query": {
      "intervention": "High CPAP Wean"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T02:52:54.114Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01939067",
      "title": "Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Respiratory Distress",
        "Lung Injury"
      ],
      "interventions": [
        {
          "name": "Heated Humidified High Flow Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Continuous Positive Airway Pressure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "2 Hours to 72 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-09-15",
      "last_synced_at": "2026-09-09T02:52:54.114Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939067"
    },
    {
      "nct_id": "NCT03464396",
      "title": "Prematurity-Related Ventilatory Control",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Control in Premature Infants"
      ],
      "interventions": [
        {
          "name": "Bedside Physiology study",
          "type": "OTHER"
        },
        {
          "name": "Carotid Body Function Test",
          "type": "OTHER"
        },
        {
          "name": "Room Air Challenge",
          "type": "OTHER"
        },
        {
          "name": "Hypoxia Challenge Test",
          "type": "OTHER"
        },
        {
          "name": "Effects of Nasal Cannula Flow",
          "type": "OTHER"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Echocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "1 Day to 28 Days"
      },
      "enrollment_count": 177,
      "start_date": "2018-05-14",
      "completion_date": "2022-03-09",
      "has_results": false,
      "last_update_posted_date": "2023-01-31",
      "last_synced_at": "2026-09-09T02:52:54.114Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03464396"
    },
    {
      "nct_id": "NCT02064712",
      "title": "Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Premature"
      ],
      "interventions": [
        {
          "name": "Low CPAP Wean",
          "type": "OTHER"
        },
        {
          "name": "High CPAP Wean",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "Up to 32 Weeks"
      },
      "enrollment_count": 226,
      "start_date": "2014-09",
      "completion_date": "2018-10",
      "has_results": false,
      "last_update_posted_date": "2018-10-22",
      "last_synced_at": "2026-09-09T02:52:54.114Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02064712"
    },
    {
      "nct_id": "NCT03473171",
      "title": "Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Nasal non-invasive ventilation with RAM cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "1 Day to 21 Years"
      },
      "enrollment_count": 5,
      "start_date": "2016-06-27",
      "completion_date": "2019-05-13",
      "has_results": true,
      "last_update_posted_date": "2020-03-24",
      "last_synced_at": "2026-09-09T02:52:54.114Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03473171"
    },
    {
      "nct_id": "NCT05547139",
      "title": "Impact of Extended CPAP on Bronchopulmonary Dysplasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Prematurity"
      ],
      "interventions": [
        {
          "name": "Protocolized weaning of respiratory support",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "30 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 30 Weeks"
      },
      "enrollment_count": 20,
      "start_date": "2022-10-10",
      "completion_date": "2024-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-29",
      "last_synced_at": "2026-09-09T02:52:54.114Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05547139"
    }
  ]
}