{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Dose+Supplement",
    "query": {
      "intervention": "High Dose Supplement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 113,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Dose+Supplement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T21:39:23.505Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06672874",
      "title": "Fermented Papaya and Driving Simulator Older Adult Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Fermented Papaya Preparation (FPP)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "70 Years to 80 Years"
      },
      "enrollment_count": 34,
      "start_date": "2025-03-19",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672874"
    },
    {
      "nct_id": "NCT06262880",
      "title": "Dietary Supplementation on Gastrointestinal Barrier Function",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intestinal Permeability"
      ],
      "interventions": [
        {
          "name": "plant derived phenolics",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Microcrystaline cellulose (MCC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Brightseed",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "30 Years to 69 Years"
      },
      "enrollment_count": 126,
      "start_date": "2024-02-06",
      "completion_date": "2025-02-06",
      "has_results": false,
      "last_update_posted_date": "2024-03-08",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06262880"
    },
    {
      "nct_id": "NCT07619976",
      "title": "Effects of New Zealand Blackcurrant Supplementation on Exercise and Cognitive Performance in Resistance-Trained Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Resistance Exercise Performance",
        "Cognitive Function",
        "Anaerobic Performance",
        "Dietary Supplementation Athletic Performance"
      ],
      "interventions": [
        {
          "name": "Low-dose Blackcurrant Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High-dose Blackcurrant Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Maltodextrin (Placebo)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Jacksonville State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-01-21",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Alabama",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07619976"
    },
    {
      "nct_id": "NCT04729816",
      "title": "Assessing the Dose Response of a Lead Fiber Snack Prototype",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Microbiota",
        "Gastrointestinal Microbiome"
      ],
      "interventions": [
        {
          "name": "Controlled, high fat/low fiber diet background diet, sequentially supplemented with an escalating dose of a fiber-blend snack food.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 17,
      "start_date": "2021-02-22",
      "completion_date": "2021-11-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-27",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04729816"
    },
    {
      "nct_id": "NCT00915200",
      "title": "N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Nephropathies",
        "Proteinuria",
        "Oxidative Stress"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "silibin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "high-dose silibin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "N-acetylcysteine placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "silibin placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 114,
      "start_date": "2009-10",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-06-27",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00915200"
    },
    {
      "nct_id": "NCT05009498",
      "title": "Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vitamin D Deficiency",
        "Rotator Cuff Tears"
      ],
      "interventions": [
        {
          "name": "Vitamin D3 supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Community Memorial Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 240,
      "start_date": "2021-09-01",
      "completion_date": "2024-08-01",
      "has_results": false,
      "last_update_posted_date": "2021-08-17",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 2,
      "location_summary": "Ventura, California",
      "locations": [
        {
          "city": "Ventura",
          "state": "California"
        },
        {
          "city": "Ventura",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05009498"
    },
    {
      "nct_id": "NCT02661334",
      "title": "Measuring Uniformed Servicemembers' Fitness Scores on Creatine Loading and Exercise",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Fitness"
      ],
      "interventions": [
        {
          "name": "Creatine Monohydrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Rice Flour",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "David Grant U.S. Air Force Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 6,
      "start_date": "2015-08-01",
      "completion_date": "2018-02-13",
      "has_results": false,
      "last_update_posted_date": "2020-04-03",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Fairfield, California",
      "locations": [
        {
          "city": "Fairfield",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02661334"
    },
    {
      "nct_id": "NCT01268176",
      "title": "The Effect of a Meal on Vitamin D Absorption",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vitamin D Deficiency"
      ],
      "interventions": [
        {
          "name": "cholecalciferol",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "50 Years to 69 Years"
      },
      "enrollment_count": 62,
      "start_date": "2010-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-05-13",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01268176"
    },
    {
      "nct_id": "NCT04749576",
      "title": "Saffron as Anti Inflammatory Agent In Patients With Inflammatory Bowel Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ulcerative Colitis"
      ],
      "interventions": [
        {
          "name": "saffron supplement for IBD",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Howard University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-12-15",
      "completion_date": "2023-12-10",
      "has_results": false,
      "last_update_posted_date": "2021-02-11",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04749576"
    },
    {
      "nct_id": "NCT03383835",
      "title": "Study of Moderate Dose Omega 3 Fatty Acid Supplement in Premenopausal Women at High Risk for Breast Cancer",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Omega-3 Supplementation",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lauren Nye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 40 Years · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2018-02-05",
      "completion_date": "2024-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-23",
      "last_synced_at": "2026-09-03T21:39:23.505Z",
      "location_count": 1,
      "location_summary": "Westwood, Kansas",
      "locations": [
        {
          "city": "Westwood",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03383835"
    }
  ]
}