{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+IOP+Setting",
    "query": {
      "intervention": "High IOP Setting"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T20:27:05.294Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06904404",
      "title": "Physiologic Phacofluidics: Ghost Protocol",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Cataract surgery at high IOP",
          "type": "PROCEDURE"
        },
        {
          "name": "Cataract surgery at low IOP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Wolfe Eye Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "55 Years to 95 Years"
      },
      "enrollment_count": 66,
      "start_date": "2024-01-01",
      "completion_date": "2024-10-31",
      "has_results": true,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "Hiawatha, Iowa",
      "locations": [
        {
          "city": "Hiawatha",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06904404"
    },
    {
      "nct_id": "NCT07762053",
      "title": "Clinical Investigation of Eye C Better's Photobionic Intraocular Pressure Biomonitor Tonometer",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elevated Intraocular Pressure (IOP)"
      ],
      "interventions": [
        {
          "name": "Photobionic IOP Tonometer (PIB)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "EyeCBetter Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 15,
      "start_date": "2026-08",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "La Quinta, California",
      "locations": [
        {
          "city": "La Quinta",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07762053"
    },
    {
      "nct_id": "NCT05495555",
      "title": "The Cutting Efficiency of Hybrid Tips in Different Grades of Cataract",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "INTREPID® Hybrid tip",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cataract and Laser Institute of Southern Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2022-08-03",
      "completion_date": "2024-02-07",
      "has_results": true,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "Medford, Oregon",
      "locations": [
        {
          "city": "Medford",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05495555"
    },
    {
      "nct_id": "NCT03808688",
      "title": "Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glaucoma, Open-Angle",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Netarsudil Ophthalmic Solution 0.02%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aerie Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 261,
      "start_date": "2018-12-27",
      "completion_date": "2019-07-26",
      "has_results": true,
      "last_update_posted_date": "2020-09-29",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 22,
      "location_summary": "Huntington Beach, California • Laguna Hills, California • Petaluma, California + 18 more",
      "locations": [
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        },
        {
          "city": "Largo",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03808688"
    },
    {
      "nct_id": "NCT07641738",
      "title": "Collecting Data on Retinal Blood Blood Flow and Blood Vessel Shape/Appearance Using an Investigational Device, XyCAM CRE, and to Then Compare Those Images With Images Collected From a Patient's Routine Clinical Examination.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Microvascular Disease",
        "Retinal Disease"
      ],
      "interventions": [
        {
          "name": "XyCAM CRE Imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stuart Terry Eye Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 350,
      "start_date": "2026-06-15",
      "completion_date": "2030-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07641738"
    },
    {
      "nct_id": "NCT05868772",
      "title": "What is the Efficiency When Comparing Active Sentry at Low IOP vs Ozil at High IOP?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Active Sentry Handpiece",
          "type": "DEVICE"
        },
        {
          "name": "Ozil Handpiece",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cataract and Laser Institute of Southern Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2023-05-16",
      "completion_date": "2024-04-19",
      "has_results": true,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "Medford, Oregon",
      "locations": [
        {
          "city": "Medford",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05868772"
    },
    {
      "nct_id": "NCT07223866",
      "title": "The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract and IOL Surgery",
        "Cataract Surgery Anesthesia",
        "Cataract Surgery Experience",
        "Nuclear Cataract"
      ],
      "interventions": [
        {
          "name": "High IOP Setting",
          "type": "DEVICE"
        },
        {
          "name": "Low IOP Setting",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Matthew Rauen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2025-11-01",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "West Des Moines, Iowa",
      "locations": [
        {
          "city": "West Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223866"
    },
    {
      "nct_id": "NCT07144644",
      "title": "2311 TURGOR Study -Surgical Efficiency and Postoperative Corneal Clarity With Near Physiologic vs High IOP Settings",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intraocular Pressure"
      ],
      "interventions": [
        {
          "name": "Adjusting intraocular pressure (IOP) settings",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Research Insight LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2024-07-26",
      "completion_date": "2025-08-06",
      "has_results": false,
      "last_update_posted_date": "2025-08-27",
      "last_synced_at": "2026-09-07T20:27:05.294Z",
      "location_count": 1,
      "location_summary": "Laguna Hills, California",
      "locations": [
        {
          "city": "Laguna Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07144644"
    }
  ]
}