{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Velocity+Low+Amplitude",
    "query": {
      "intervention": "High Velocity Low Amplitude"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 92,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Velocity+Low+Amplitude&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T10:02:17.848Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07064772",
      "title": "The Immediate Effects of First Rib Mobilization on Pain and Range of Motion in Patients With Shoulder Pain",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "First Rib Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Sham Comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Andrews University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 64,
      "start_date": "2025-07-14",
      "completion_date": "2026-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Annville, Pennsylvania",
      "locations": [
        {
          "city": "Annville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07064772"
    },
    {
      "nct_id": "NCT05401903",
      "title": "Relationship Between Chiropractic Care and Autonomic Nervous System Regulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chiropractic Maintenance Care and Heart Rate Variability"
      ],
      "interventions": [
        {
          "name": "Chiropractic Maintenance Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northeast College of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-06-01",
      "completion_date": "2023-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Seneca Falls, New York",
      "locations": [
        {
          "city": "Seneca Falls",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05401903"
    },
    {
      "nct_id": "NCT03250312",
      "title": "The Effects of OMT on the Expression Patterns of Immune Cell Biomarkers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteopathic Manipulation",
        "Low Back Pain",
        "Biomarkers"
      ],
      "interventions": [
        {
          "name": "The Osteopathic Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "A.T. Still University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-09-13",
      "completion_date": "2019-08-31",
      "has_results": false,
      "last_update_posted_date": "2020-01-13",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Kirksville, Missouri",
      "locations": [
        {
          "city": "Kirksville",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03250312"
    },
    {
      "nct_id": "NCT02670148",
      "title": "Assessment of Chiropractic Treatment: Strength and Balance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Chiropractic manipulative therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Ian Coulter",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 110,
      "start_date": "2016-04",
      "completion_date": "2019-02-14",
      "has_results": false,
      "last_update_posted_date": "2019-03-28",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Pensacola, Florida",
      "locations": [
        {
          "city": "Pensacola",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02670148"
    },
    {
      "nct_id": "NCT03176654",
      "title": "The Effect of Manipulation of the Cervical Spine on Pain Biomarkers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain, Posterior"
      ],
      "interventions": [
        {
          "name": "HVLAT manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham HVLAT manipulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 45 Years · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2016-08-15",
      "completion_date": "2016-09-20",
      "has_results": true,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03176654"
    },
    {
      "nct_id": "NCT03483714",
      "title": "Muscle Activation Characteristics During Spinal Manipulation in Healthy and Low Back Pain Participants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 60,
      "start_date": "2011-02-01",
      "completion_date": "2015-11-05",
      "has_results": false,
      "last_update_posted_date": "2018-03-30",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03483714"
    },
    {
      "nct_id": "NCT01188837",
      "title": "Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Full Kinetic Chain Manipulative Therapy",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Manipulative Therapy with Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cleveland Chiropractic College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "38 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "38 Years to 80 Years"
      },
      "enrollment_count": 144,
      "start_date": "2010-09",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-08-09",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01188837"
    },
    {
      "nct_id": "NCT01211613",
      "title": "Chiropractic Manipulation and Medical Care for Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Manual Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Mechanically-assisted manipulation",
          "type": "DEVICE"
        },
        {
          "name": "Standard Medical Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2010-11",
      "completion_date": "2013-10",
      "has_results": true,
      "last_update_posted_date": "2017-01-30",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01211613"
    },
    {
      "nct_id": "NCT01743833",
      "title": "Effects of Thoracic Orthopedic Manual Therapy and Biopsychosocial Variables on Signs of Shoulder Impingement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Impingement"
      ],
      "interventions": [
        {
          "name": "Thoracic High Velocity, Low Amplitude Thrust Maneuver (HVLATM)",
          "type": "OTHER"
        },
        {
          "name": "Scapular High Velocity, Low Amplitude Thrust Maneuver",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "18 Years to 69 Years"
      },
      "enrollment_count": 97,
      "start_date": "2011-06",
      "completion_date": "2012-12-05",
      "has_results": false,
      "last_update_posted_date": "2017-04-26",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01743833"
    },
    {
      "nct_id": "NCT00394264",
      "title": "How Does Manual Therapy Improve Low Back Pain for Soldiers?",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Soft Tissue",
          "type": "PROCEDURE"
        },
        {
          "name": "Myofascial release",
          "type": "PROCEDURE"
        },
        {
          "name": "Counterstrain",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle energy",
          "type": "PROCEDURE"
        },
        {
          "name": "Sacro-iliac articulation",
          "type": "PROCEDURE"
        },
        {
          "name": "High-velocity, low amplitude",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "17 Years to 35 Years"
      },
      "enrollment_count": 100,
      "start_date": "2006-10",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2006-10-31",
      "last_synced_at": "2026-09-22T10:02:17.848Z",
      "location_count": 1,
      "location_summary": "Fort Lewis, Washington",
      "locations": [
        {
          "city": "Fort Lewis",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00394264"
    }
  ]
}