{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Velocity+Low+Amplitude+mobilization",
    "query": {
      "intervention": "High Velocity Low Amplitude mobilization"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 30,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+Velocity+Low+Amplitude+mobilization&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T11:32:01.079Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01571674",
      "title": "Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "Manipulation + Exercise Group",
          "type": "PROCEDURE"
        },
        {
          "name": "Exercise Group",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 140,
      "start_date": "2012-01",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 9,
      "location_summary": "Aurora, Colorado • Boulder, Colorado • Concord, New Hampshire + 5 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Concord",
          "state": "New Hampshire"
        },
        {
          "city": "Shiprock",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01571674"
    },
    {
      "nct_id": "NCT04386590",
      "title": "Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease Moderate"
      ],
      "interventions": [
        {
          "name": "Manual Therapy Plus Pulmonary Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Sham Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Canandaigua VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-15",
      "completion_date": "2023-11-02",
      "has_results": false,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04386590"
    },
    {
      "nct_id": "NCT02036905",
      "title": "Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Cervical and thoracic mobilization",
          "type": "OTHER"
        },
        {
          "name": "cervical and thoracic manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Youngstown State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2013-07",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-01-26",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 2,
      "location_summary": "Solon, Ohio • Havertown, Pennsylvania",
      "locations": [
        {
          "city": "Solon",
          "state": "Ohio"
        },
        {
          "city": "Havertown",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02036905"
    },
    {
      "nct_id": "NCT01188837",
      "title": "Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Full Kinetic Chain Manipulative Therapy",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Manipulative Therapy with Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cleveland Chiropractic College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "38 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "38 Years to 80 Years"
      },
      "enrollment_count": 144,
      "start_date": "2010-09",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-08-09",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01188837"
    },
    {
      "nct_id": "NCT01434966",
      "title": "Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain Syndrome",
        "Chondromalacia Patellae",
        "Anterior Knee Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Lumbopelvic Manipulation",
          "type": "OTHER"
        },
        {
          "name": "TENS- Spine",
          "type": "OTHER"
        },
        {
          "name": "TENS- Knee",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "15 Years to 50 Years"
      },
      "enrollment_count": 47,
      "start_date": "2011-09",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01434966"
    },
    {
      "nct_id": "NCT03428620",
      "title": "Effect of Mobilization in Conjunction With Exercise in Participants With a History of Chronic Ankle Instability",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains"
      ],
      "interventions": [
        {
          "name": "High Velocity Low Amplitude mobilization",
          "type": "OTHER"
        },
        {
          "name": "Exercise protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 50,
      "start_date": "2018-02-14",
      "completion_date": "2019-06",
      "has_results": false,
      "last_update_posted_date": "2018-04-17",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 2,
      "location_summary": "Fayetteville, North Carolina • Winchester, Virginia",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "North Carolina"
        },
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03428620"
    },
    {
      "nct_id": "NCT03918473",
      "title": "Effects of Mobilization Versus Manipulation on Function in Participants Reporting CAI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains"
      ],
      "interventions": [
        {
          "name": "Mobilization with Movement",
          "type": "OTHER"
        },
        {
          "name": "Thrust Mobilization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 50,
      "start_date": "2019-04",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2019-04-17",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Winchester, Virginia",
      "locations": [
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03918473"
    },
    {
      "nct_id": "NCT03749564",
      "title": "Influence of Opioid Use on the Effects of Spinal Manipulative Therapy for Low Back Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "SMT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Activation Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobilizing Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Extended SMT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 7,
      "start_date": "2019-01-17",
      "completion_date": "2020-03-03",
      "has_results": false,
      "last_update_posted_date": "2022-09-22",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03749564"
    },
    {
      "nct_id": "NCT00475787",
      "title": "Chiropractic Management of Chronic Lower Back Pain in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Detuned Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2008-04",
      "completion_date": "2011-04",
      "has_results": true,
      "last_update_posted_date": "2014-12-30",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 2,
      "location_summary": "Buffalo, New York • Canandaigua, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Canandaigua",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475787"
    },
    {
      "nct_id": "NCT01438905",
      "title": "Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Small amplitude (Grade IV) mobilization",
          "type": "OTHER"
        },
        {
          "name": "High velocity, low amplitude (Grade V) mobilization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "19 Years to 45 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2011-09",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2018-02-23",
      "last_synced_at": "2026-09-30T11:32:01.079Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01438905"
    }
  ]
}