{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+flow+nasal+oxygen&page=3",
    "query": {
      "intervention": "High flow nasal oxygen",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 84,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+flow+nasal+oxygen&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+flow+nasal+oxygen&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T10:52:35.618Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03333174",
      "title": "Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant,Premature"
      ],
      "interventions": [
        {
          "name": "Cardiorespiratory monitoring",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "98 Days",
        "sex": "ALL",
        "summary": "1 Day to 98 Days"
      },
      "enrollment_count": 25,
      "start_date": "2018-04-09",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-09-21",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03333174"
    },
    {
      "nct_id": "NCT02968706",
      "title": "HFNC Versus Conventional Nasal Cannula in Oxygen Performance in Patients Receiving Colonoscopy Under IV Sedation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Desaturation of Blood"
      ],
      "interventions": [
        {
          "name": "High Flow Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Patient satisfaction questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Aventura Hospital and Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2017-01",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-20",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Aventura, Florida",
      "locations": [
        {
          "city": "Aventura",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02968706"
    },
    {
      "nct_id": "NCT02858154",
      "title": "Comparison of High Flow Nasal Cannula Therapy to Nasal Oxygen as a Treatment for Obstructive Sleep Apnea in Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "HFNC",
          "type": "OTHER"
        },
        {
          "name": "Low flow oxygen by nasal cannula",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "1 Day to 12 Months"
      },
      "enrollment_count": 9,
      "start_date": "2016-02",
      "completion_date": "2021-07-26",
      "has_results": true,
      "last_update_posted_date": "2022-03-15",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 2,
      "location_summary": "Kansas City, Kansas • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02858154"
    },
    {
      "nct_id": "NCT07452406",
      "title": "Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Hypoxemic Respiratory Failure",
        "High-Flow Nasal Cannula Therapy"
      ],
      "interventions": [
        {
          "name": "Protocolized HFNC Weaning Strategy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care HFNC Weaning",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2026-11-01",
      "completion_date": "2028-06-28",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07452406"
    },
    {
      "nct_id": "NCT03214458",
      "title": "Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Nasal high flow",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Temple University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2017-07-20",
      "completion_date": "2018-04-18",
      "has_results": false,
      "last_update_posted_date": "2018-04-19",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03214458"
    },
    {
      "nct_id": "NCT01925534",
      "title": "Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure",
        "Treatment With Noninvasive Positive Pressure Ventilation"
      ],
      "interventions": [
        {
          "name": "High-flow humidified nasal oxygen delivery system",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2013-11",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Winchester, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Winchester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01925534"
    },
    {
      "nct_id": "NCT04353531",
      "title": "Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transmission, Patient Professional",
        "High-flow Nasal Cannula"
      ],
      "interventions": [
        {
          "name": "High-flow nasal cannula",
          "type": "DEVICE"
        },
        {
          "name": "Surgical mask",
          "type": "DEVICE"
        },
        {
          "name": "bronchoscopy examination",
          "type": "PROCEDURE"
        },
        {
          "name": "intubation",
          "type": "PROCEDURE"
        },
        {
          "name": "tracheostomy",
          "type": "PROCEDURE"
        },
        {
          "name": "nebulization",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary function test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2020-05-20",
      "completion_date": "2020-08-30",
      "has_results": false,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04353531"
    },
    {
      "nct_id": "NCT02859597",
      "title": "Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Morbid Obesity",
        "Noninvasive Ventilation",
        "Deep Sedation"
      ],
      "interventions": [
        {
          "name": "High flow nasal cannula",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2016-12-28",
      "completion_date": "2018-09-28",
      "has_results": true,
      "last_update_posted_date": "2020-04-16",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02859597"
    },
    {
      "nct_id": "NCT01672242",
      "title": "Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adult Volunteers"
      ],
      "interventions": [
        {
          "name": "HFNC",
          "type": "DEVICE"
        },
        {
          "name": "CPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 6,
      "start_date": "2012-07",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2022-03-08",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01672242"
    },
    {
      "nct_id": "NCT04035460",
      "title": "A Pilot Study Comparing Oxygen Delivery Via Helmet Interface Versus High Flow Nasal Cannula",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemic Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Helmet",
          "type": "DEVICE"
        },
        {
          "name": "High Flow Nasal Oxygen",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baystate Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2018-06-01",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-10-02T10:52:35.618Z",
      "location_count": 1,
      "location_summary": "Springfield, Massachusetts",
      "locations": [
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04035460"
    }
  ]
}