{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+fructose+corn+syrup+diet",
    "query": {
      "intervention": "High fructose corn syrup diet"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High+fructose+corn+syrup+diet&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T07:56:19.439Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01103921",
      "title": "The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Insulin Resistance",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Glucose",
          "type": "OTHER"
        },
        {
          "name": "Fructose",
          "type": "OTHER"
        },
        {
          "name": "High-Fructose Corn Syrup",
          "type": "OTHER"
        },
        {
          "name": "No sugar (Aspartame)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 214,
      "start_date": "2008-10",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01103921"
    },
    {
      "nct_id": "NCT07105826",
      "title": "Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Olipop",
        "Poppi",
        "Coca Cola - Classic",
        "Diet Coke"
      ],
      "interventions": [
        {
          "name": "Prebiotic Soda 1",
          "type": "OTHER"
        },
        {
          "name": "Prebiotic Soda 2",
          "type": "OTHER"
        },
        {
          "name": "Diet Soda",
          "type": "OTHER"
        },
        {
          "name": "Regular Coke",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Christian University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2025-08-04",
      "completion_date": "2026-03-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07105826"
    },
    {
      "nct_id": "NCT02094768",
      "title": "Soda and Milk Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Reduced Fat Milk",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Sugar Sweetened Soda",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "UCSF Benioff Children's Hospital Oakland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "MALE",
        "summary": "13 Years to 18 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2014-04",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Berkeley, California",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02094768"
    },
    {
      "nct_id": "NCT02018237",
      "title": "High Fructose Corn Syrup",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nonalcoholic Fatty Liver Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "High fructose corn syrup diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard diet (low in high fructose corn syrup)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 47,
      "start_date": "2012-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-27",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02018237"
    },
    {
      "nct_id": "NCT02548767",
      "title": "Adverse Metabolic Effects of Dietary Sugar",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Disease of Cardiovascular System",
        "Type 2 Diabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "high fructose corn syrup",
          "type": "OTHER"
        },
        {
          "name": "aspartame",
          "type": "OTHER"
        },
        {
          "name": "Energy-balanced diet",
          "type": "OTHER"
        },
        {
          "name": "Ad libitum diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-02",
      "completion_date": "2020-03-13",
      "has_results": false,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 3,
      "location_summary": "Davis, California • Sacramento, California • Vallejo, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Vallejo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02548767"
    },
    {
      "nct_id": "NCT01797042",
      "title": "A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Dietary Compliance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rippe Lifestyle Institute",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "20 Years to 60 Years"
      },
      "enrollment_count": 366,
      "start_date": "2012-03",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2014-09-30",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Celebration, Florida",
      "locations": [
        {
          "city": "Celebration",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01797042"
    },
    {
      "nct_id": "NCT04308473",
      "title": "Analysis of MicroBial Metabolites After Eating Refined Food",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Ultra-processed Food Meal",
          "type": "OTHER"
        },
        {
          "name": "Whole Food Meal",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2020-09-01",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04308473"
    },
    {
      "nct_id": "NCT01424306",
      "title": "Diet and Systemic Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low-grade Chronic Inflammation",
        "Intestinal Permeability",
        "Type 2 Diabetes Mellitus",
        "Cardiovascular Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Fructose-sweetened beverages",
          "type": "OTHER"
        },
        {
          "name": "Glucose-sweetened beverages",
          "type": "OTHER"
        },
        {
          "name": "High-fructose corn syrup-sweetened beverages",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2011-10",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2017-08-14",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424306"
    },
    {
      "nct_id": "NCT03241706",
      "title": "Liver Glycogen and Hypoglycemia in Humans",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoglycemia; Iatrogenic"
      ],
      "interventions": [
        {
          "name": "Low Fructose",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Somatostatin",
          "type": "DRUG"
        },
        {
          "name": "Insulin",
          "type": "DRUG"
        },
        {
          "name": "Glucagon",
          "type": "DRUG"
        },
        {
          "name": "Dextrose solution",
          "type": "DRUG"
        },
        {
          "name": "High Fructose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jason Winnick",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-08-02",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-25",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241706"
    },
    {
      "nct_id": "NCT01610661",
      "title": "Dietary Carbohydrate Type and Cardiovascular Disease (CVD) Risk Indicators",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2012-01",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-07-13",
      "last_synced_at": "2026-09-25T07:56:19.439Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01610661"
    }
  ]
}