{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-Dose+Methylprednisolone", "query": { "intervention": "High-Dose Methylprednisolone" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 93, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-Dose+Methylprednisolone&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T09:58:07.358Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02528214", "title": "Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Dupilumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Oral corticosteroid therapy (prednisone/prednisolone)", "type": "DRUG" }, { "name": "Inhaled corticosteroid (ICS) therapy", "type": "DRUG" }, { "name": "Albuterol/Salbutamol", "type": "DRUG" }, { "name": "Levalbuterol/Levosalbutamol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 210, "start_date": "2015-10-15", "completion_date": "2017-11-13", "has_results": true, "last_update_posted_date": "2019-10-01", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 8, "location_summary": "Los Angeles, California • Rolling Hills Estates, California • St Louis, Missouri + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Amarillo", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02528214" }, { "nct_id": "NCT01559675", "title": "Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Orthostatic Hypotension", "Hemodynamic Instability", "Fever", "Hypothermia" ], "interventions": [ { "name": "Hydrocortisone High Dose", "type": "DRUG" }, { "name": "Hydrocortisone Low Dose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 121, "start_date": "2010-09", "completion_date": "2012-04", "has_results": true, "last_update_posted_date": "2018-03-29", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01559675" }, { "nct_id": "NCT02670707", "title": "Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Langerhans Cell Histiocytosis" ], "interventions": [ { "name": "Cytarabine", "type": "DRUG" }, { "name": "Vinblastine/prednisone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 124, "start_date": "2016-03-07", "completion_date": "2029-01", "has_results": false, "last_update_posted_date": "2025-09-11", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 11, "location_summary": "Palo Alto, California • San Diego, California • Minneapolis, Minnesota + 8 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Allentown", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02670707" }, { "nct_id": "NCT00003336", "title": "Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia", "Myelodysplastic Syndromes", "Myelodysplastic/Myeloproliferative Diseases" ], "interventions": [ { "name": "anti-thymocyte globulin", "type": "BIOLOGICAL" }, { "name": "busulfan", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "methylprednisolone", "type": "DRUG" }, { "name": "bone marrow ablation with stem cell support", "type": "PROCEDURE" }, { "name": "umbilical cord blood transplantation", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "55 Years", "sex": "ALL", "summary": "Up to 55 Years" }, "enrollment_count": 6, "start_date": "1998-01", "completion_date": "2006-02", "has_results": false, "last_update_posted_date": "2010-06-11", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003336" }, { "nct_id": "NCT00002831", "title": "Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Leukemia" ], "interventions": [ { "name": "Filgrastim", "type": "BIOLOGICAL" }, { "name": "Busulfan", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" }, { "name": "Decitabine (DAC)", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Allogeneic Bone Marrow Transplantation", "type": "PROCEDURE" }, { "name": "Peripheral Blood Stem Cell Transplantation", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "15 Years to 55 Years" }, "enrollment_count": 24, "start_date": "1995-08-01", "completion_date": "2002-12-31", "has_results": false, "last_update_posted_date": "2018-10-26", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002831" }, { "nct_id": "NCT05707156", "title": "Prospective Observational Study on the Incidence of Opportunistic Fungal Infections", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pneumocystis Jirovecii Infection", "Pneumocystis", "Cryptococcosis", "Candidiasis", "Aspergillosis" ], "interventions": [], "intervention_types": [], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12032, "start_date": "2023-07-05", "completion_date": "2024-01-05", "has_results": false, "last_update_posted_date": "2025-04-02", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05707156" }, { "nct_id": "NCT04349410", "title": "The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "CoVid 19 Positive" ], "interventions": [ { "name": "Hydroxychloroquine, Azithromycin", "type": "DRUG" }, { "name": "Hydroxychloroquine, Doxycycline", "type": "DRUG" }, { "name": "Hydroxychloroquine, Clindamycin", "type": "DRUG" }, { "name": "Hydroxychloroquine, Clindamycin, Primaquine - low dose.", "type": "DRUG" }, { "name": "Hydroxychloroquine, Clindamycin, Primaquine - high dose.", "type": "DRUG" }, { "name": "Remdesivir", "type": "DRUG" }, { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Interferon-Alpha2B", "type": "DRUG" }, { "name": "Losartan", "type": "DRUG" }, { "name": "Convalescent Serum", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Camelot Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1800, "start_date": "2020-04-11", "completion_date": "2020-09-14", "has_results": false, "last_update_posted_date": "2020-11-12", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04349410" }, { "nct_id": "NCT01900093", "title": "Evaluation of the Response to Acthar Gel Therapy in Patients Who Failed Intravenous Methylprednisolone (IVMP) for MS Relapses", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Multiple Sclerosis" ], "interventions": [ { "name": "Acthar Gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aaron Miller", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2013-07", "completion_date": "2018-03", "has_results": false, "last_update_posted_date": "2017-09-06", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01900093" }, { "nct_id": "NCT07287397", "title": "Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "VTx-002", "type": "GENETIC" }, { "name": "Preventative (Prophylactic) Medication - Corticosteroids: Methylprednisolone", "type": "DRUG" } ], "intervention_types": [ "GENETIC", "DRUG" ], "sponsor": "Vector Y Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12, "start_date": "2025-12-19", "completion_date": "2027-10-15", "has_results": false, "last_update_posted_date": "2026-09-10", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 7, "location_summary": "Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07287397" }, { "nct_id": "NCT04151082", "title": "High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Cranial Nerve Disorder", "Head and Neck Carcinoma", "Oropharyngeal Carcinoma" ], "interventions": [ { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2019-10-16", "completion_date": "2027-07-31", "has_results": false, "last_update_posted_date": "2026-06-26", "last_synced_at": "2026-09-24T09:58:07.358Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04151082" } ] }