{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-Flow+Therapy&page=2",
    "query": {
      "intervention": "High-Flow Therapy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-Flow+Therapy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T04:20:32.532Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05863039",
      "title": "Resistance Training With Blood Flow Restriction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Blood flow restriction",
          "type": "OTHER"
        },
        {
          "name": "Regular training type 1",
          "type": "OTHER"
        },
        {
          "name": "Regular training type 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 8,
      "start_date": "2022-11-01",
      "completion_date": "2026-04-27",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "Norman, Oklahoma",
      "locations": [
        {
          "city": "Norman",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05863039"
    },
    {
      "nct_id": "NCT00990119",
      "title": "High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Vapotherm High Flow Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Non-invasive positive pressure ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2009-09",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00990119"
    },
    {
      "nct_id": "NCT04709562",
      "title": "Clinical Stabilization of Hypercapnia: NIPPV v HVNI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypercapnic Respiratory Failure",
        "Chronic Obstructive Pulmonary Disease",
        "Dyspnea",
        "Hypercapnic Acidosis"
      ],
      "interventions": [
        {
          "name": "High Velocity Nasal Insufflation (HVNI)",
          "type": "DEVICE"
        },
        {
          "name": "Noninvasive Positive Pressure Ventilation (NIPPV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2020-11-11",
      "completion_date": "2023-06-22",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Oxnard, California • Washington D.C., District of Columbia + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oxnard",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04709562"
    },
    {
      "nct_id": "NCT04971148",
      "title": "Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemic Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "HFNC flow set at patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 1.33 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 1.67 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 2 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 5,
      "start_date": "2022-04-07",
      "completion_date": "2023-08-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04971148"
    },
    {
      "nct_id": "NCT04832061",
      "title": "Respiratory Supports and COVID-19 Mortality",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Respiratory supports",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2300,
      "start_date": "2021-04-01",
      "completion_date": "2021-04-20",
      "has_results": false,
      "last_update_posted_date": "2021-05-13",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04832061"
    },
    {
      "nct_id": "NCT07168993",
      "title": "Evaluate the Clinical Performance of the Flow Cytometry - FlowPath Lung Test as a Sensitive and Specific Non-invasive Diagnostic of Sputum Samples to Identify/Detect the Presence of Lung Cancer in High-risk Individuals Who Have Existing Lung Nodules, 6 to <30 mm in Diameter, Determined by LDCT.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Cancer (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "Standard medical treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "bioAffinity Technologies Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 2063,
      "start_date": "2026-02-25",
      "completion_date": "2029-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 11,
      "location_summary": "Palo Alto, California • Grand Junction, Colorado • Bay Pines, Florida + 7 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Grand Junction",
          "state": "Colorado"
        },
        {
          "city": "Bay Pines",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07168993"
    },
    {
      "nct_id": "NCT02325687",
      "title": "A Pilot Study of Biomarkers in Obstructive Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Lumbar Puncture (Standard-of-Care)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "50 Years to 84 Years"
      },
      "enrollment_count": 50,
      "start_date": "2015-01",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2020-04-21",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02325687"
    },
    {
      "nct_id": "NCT01268319",
      "title": "CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Atherosclerosis",
        "Myocardial Infarction",
        "Coronary Plaque Embolization"
      ],
      "interventions": [
        {
          "name": "Embolic Protection Device (EPD)",
          "type": "DEVICE"
        },
        {
          "name": "Intracoronary Spectroscopy and Ultrasonic Evaluation",
          "type": "DEVICE"
        },
        {
          "name": "Angioplasty and Stent Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Infraredx",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2011-05",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2017-06-12",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 9,
      "location_summary": "Scottsdale, Arizona • San Francisco, California • Washington D.C., District of Columbia + 6 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01268319"
    },
    {
      "nct_id": "NCT00784823",
      "title": "Study Combining Bortezomib With High Dose Melphalan to Treat Multiple Myeloma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Multiple Myeloma"
      ],
      "interventions": [
        {
          "name": "Bortezomib 1 mg/m2",
          "type": "DRUG"
        },
        {
          "name": "Bortezomib 1.3 mg/m2",
          "type": "DRUG"
        },
        {
          "name": "Bortezomib 1.6 mg/m2",
          "type": "DRUG"
        },
        {
          "name": "Melphalan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hackensack Meridian Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "76 Years",
        "sex": "ALL",
        "summary": "18 Years to 76 Years"
      },
      "enrollment_count": 32,
      "start_date": "2007-01",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2022-08-11",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "Hackensack, New Jersey",
      "locations": [
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00784823"
    },
    {
      "nct_id": "NCT05937672",
      "title": "Cold Atmospheric Plasma Device Extension Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Verruca Vulgaris",
        "Molluscum Contagiosum"
      ],
      "interventions": [
        {
          "name": "Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "4 Years to 21 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-09-18",
      "completion_date": "2025-12-19",
      "has_results": false,
      "last_update_posted_date": "2026-04-03",
      "last_synced_at": "2026-09-22T04:20:32.532Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05937672"
    }
  ]
}