{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-salt+diet&page=2",
    "query": {
      "intervention": "High-salt diet",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-salt+diet&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T14:49:00.213Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01547117",
      "title": "Dietary Salt in Postural Tachycardia Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Orthostatic Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Blood Volume",
          "type": "RADIATION"
        },
        {
          "name": "Total Blood Volume",
          "type": "RADIATION"
        },
        {
          "name": "Exercise Capacity Test - Bicycle",
          "type": "PROCEDURE"
        },
        {
          "name": "Posture Study",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 38,
      "start_date": "2012-03",
      "completion_date": "2021-12",
      "has_results": true,
      "last_update_posted_date": "2022-02-22",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547117"
    },
    {
      "nct_id": "NCT04585594",
      "title": "Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Medication Adherence"
      ],
      "interventions": [
        {
          "name": "Mi Propio Camino (MPC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Habilidades para Controlar la Presion (HCP; Skills for Blood Pressure Control)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 511,
      "start_date": "2020-09-16",
      "completion_date": "2024-09-10",
      "has_results": true,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04585594"
    },
    {
      "nct_id": "NCT07832942",
      "title": "Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive Hypertension (Beta2AR).",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genetics in Hypertension"
      ],
      "interventions": [
        {
          "name": "low sodium diet",
          "type": "OTHER"
        },
        {
          "name": "high sodium diet",
          "type": "OTHER"
        },
        {
          "name": "renal plasma flow",
          "type": "PROCEDURE"
        },
        {
          "name": "SIEA collection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 110,
      "start_date": "2026-11",
      "completion_date": "2030-04",
      "has_results": false,
      "last_update_posted_date": "2026-09-22",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07832942"
    },
    {
      "nct_id": "NCT06983054",
      "title": "DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "ertugliflozine",
          "type": "DRUG"
        },
        {
          "name": "low salt diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        },
        {
          "name": "high salt diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Amsterdam UMC, location VUmc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 34,
      "start_date": "2023-07-25",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06983054"
    },
    {
      "nct_id": "NCT03753204",
      "title": "Salt-Sensitivity and Immunity Cell Activation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "High Blood Pressure",
        "Salt; Excess",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Furosemide 40 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-09-01",
      "completion_date": "2026-09-15",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03753204"
    },
    {
      "nct_id": "NCT06449287",
      "title": "Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ketogenic Diet",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "OTHER"
        },
        {
          "name": "Blood Draw",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Ketone/Glucose Monitoring",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "Urine Analysis",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Neuropsychological Measures - ANAM",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL",
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 37,
      "start_date": "2018-07-05",
      "completion_date": "2019-08-21",
      "has_results": false,
      "last_update_posted_date": "2024-12-19",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06449287"
    },
    {
      "nct_id": "NCT07118592",
      "title": "Genetic Architecture of Natriuretic Peptides and Blood Pressure Response",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension (HTN)",
        "Cardiometabolic Diseases"
      ],
      "interventions": [
        {
          "name": "Low Salt Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High Salt Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Saline Infusion",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-09-01",
      "completion_date": "2030-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07118592"
    },
    {
      "nct_id": "NCT07790900",
      "title": "Gut Microbiome, Metabolome, and SSBP",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Salt-sensitivity of Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Dietary sodium",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-09-01",
      "completion_date": "2031-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07790900"
    },
    {
      "nct_id": "NCT01550315",
      "title": "Effect of Dietary Sodium Intake on Vascular Endothelium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Tachycardia Syndrome (POTS)"
      ],
      "interventions": [
        {
          "name": "Pulsitile Arterial Tonometry (PAT) Protocol",
          "type": "PROCEDURE"
        },
        {
          "name": "Calf Blood Flow in Reactive Hyperemia (CBF-RH)",
          "type": "DEVICE"
        },
        {
          "name": "Evaluation of Forearm-Mediated Dilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-04",
      "completion_date": "2021-09",
      "has_results": true,
      "last_update_posted_date": "2022-01-05",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01550315"
    },
    {
      "nct_id": "NCT04258332",
      "title": "CARDIA-Salt Sensitivity of Blood Pressure (SSBP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Salt Sensitivity of Blood Pressure",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "High Salt Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low Salt Diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 281,
      "start_date": "2021-05-17",
      "completion_date": "2025-05-17",
      "has_results": true,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-29T14:49:00.213Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04258332"
    }
  ]
}