{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=2",
    "query": {
      "intervention": "High-velocity, low amplitude",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 93,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T08:50:47.342Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06818175",
      "title": "Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Chronic Low-back Pain",
        "Acute Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia",
          "type": "PROCEDURE"
        },
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Edward Via Virginia College of Osteopathic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 200,
      "start_date": "2023-09-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06818175"
    },
    {
      "nct_id": "NCT01529151",
      "title": "Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vertigo",
        "Dizziness",
        "Benign Paroxysmal Positional Vertigo",
        "Labyrinthitis"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "OTHER"
        },
        {
          "name": "Vestibular Rehabilitation Therapy (VRT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Western University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 26,
      "start_date": "2012-01",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2015-06-10",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Pomona, California",
      "locations": [
        {
          "city": "Pomona",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01529151"
    },
    {
      "nct_id": "NCT00394264",
      "title": "How Does Manual Therapy Improve Low Back Pain for Soldiers?",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Soft Tissue",
          "type": "PROCEDURE"
        },
        {
          "name": "Myofascial release",
          "type": "PROCEDURE"
        },
        {
          "name": "Counterstrain",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle energy",
          "type": "PROCEDURE"
        },
        {
          "name": "Sacro-iliac articulation",
          "type": "PROCEDURE"
        },
        {
          "name": "High-velocity, low amplitude",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "17 Years to 35 Years"
      },
      "enrollment_count": 100,
      "start_date": "2006-10",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2006-10-31",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Fort Lewis, Washington",
      "locations": [
        {
          "city": "Fort Lewis",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00394264"
    },
    {
      "nct_id": "NCT01562756",
      "title": "Patient Response to Spinal Manipulation - Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 6,
      "start_date": "2012-02",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2017-07-31",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01562756"
    },
    {
      "nct_id": "NCT01670292",
      "title": "Patient Response to Spinal Manipulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 82,
      "start_date": "2012-09",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2017-12-05",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01670292"
    },
    {
      "nct_id": "NCT06852898",
      "title": "Comparative Clinical Trial: Manual Therapy With and Without Radial Extracorporeal Shockwave Therapy to Treat Acute Low Back Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Lower Back Pain"
      ],
      "interventions": [
        {
          "name": "Chiropractic Care",
          "type": "OTHER"
        },
        {
          "name": "Radial Extracorporeal Shockwave Therapy (ESWT) - Radial Pulse Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northeast College of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-06",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Seneca Falls, New York",
      "locations": [
        {
          "city": "Seneca Falls",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06852898"
    },
    {
      "nct_id": "NCT07641621",
      "title": "Squat Jump Performance and Chiropractic Ankle Manipulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Athletic Performance",
        "Neuromuscular Adaptations",
        "Lower Limb",
        "Chiropractic Manipulation"
      ],
      "interventions": [
        {
          "name": "Manual Therapy Procedure: Chiropractic Ankle Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northeast College of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-06",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Seneca Falls, New York",
      "locations": [
        {
          "city": "Seneca Falls",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07641621"
    },
    {
      "nct_id": "NCT02868034",
      "title": "Optimization of Spinal Manipulative Therapy Protocols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "SMT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobilizing Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Activation Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SMT extended",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 273,
      "start_date": "2017-02-22",
      "completion_date": "2019-01-12",
      "has_results": true,
      "last_update_posted_date": "2023-05-17",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02868034"
    },
    {
      "nct_id": "NCT03176654",
      "title": "The Effect of Manipulation of the Cervical Spine on Pain Biomarkers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain, Posterior"
      ],
      "interventions": [
        {
          "name": "HVLAT manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham HVLAT manipulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 45 Years · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2016-08-15",
      "completion_date": "2016-09-20",
      "has_results": true,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03176654"
    },
    {
      "nct_id": "NCT03918473",
      "title": "Effects of Mobilization Versus Manipulation on Function in Participants Reporting CAI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains"
      ],
      "interventions": [
        {
          "name": "Mobilization with Movement",
          "type": "OTHER"
        },
        {
          "name": "Thrust Mobilization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 50,
      "start_date": "2019-04",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2019-04-17",
      "last_synced_at": "2026-10-08T08:50:47.342Z",
      "location_count": 1,
      "location_summary": "Winchester, Virginia",
      "locations": [
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03918473"
    }
  ]
}