{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=4",
    "query": {
      "intervention": "High-velocity, low amplitude",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 93,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=High-velocity%2C+low+amplitude&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-11T20:06:50.633Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02054650",
      "title": "OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain",
        "Type 2 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manual Treatment (OMT)",
          "type": "OTHER"
        },
        {
          "name": "Sham OMT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 23,
      "start_date": "2014-05",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-05-26",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02054650"
    },
    {
      "nct_id": "NCT02089750",
      "title": "Orthotic Use for Chronic Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Orthotics",
          "type": "OTHER"
        },
        {
          "name": "Orthotics Plus Chiropractic Care",
          "type": "OTHER"
        },
        {
          "name": "Wait List",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 225,
      "start_date": "2014-03",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2017-03-31",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Lombard, Illinois",
      "locations": [
        {
          "city": "Lombard",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02089750"
    },
    {
      "nct_id": "NCT02619500",
      "title": "Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Home Exercise Program",
          "type": "OTHER"
        },
        {
          "name": "Patient advice, encouragement, and education",
          "type": "OTHER"
        },
        {
          "name": "Thrust Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Non-thrust Mobilizations",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Youngstown State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2016-02",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2016-02-12",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Youngstown, Ohio",
      "locations": [
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02619500"
    },
    {
      "nct_id": "NCT01188837",
      "title": "Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Full Kinetic Chain Manipulative Therapy",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Full Kinetic Chain Manipulative Therapy with Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cleveland Chiropractic College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "38 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "38 Years to 80 Years"
      },
      "enrollment_count": 144,
      "start_date": "2010-09",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-08-09",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01188837"
    },
    {
      "nct_id": "NCT01940744",
      "title": "Prescriptive Mobilization Versus a Pragmatic Mobilization",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mechanical Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Prescriptive Mobilization",
          "type": "PROCEDURE"
        },
        {
          "name": "Pragmatic Mobilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Walsh University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2013-10",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2013-11-13",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 3,
      "location_summary": "Des Moines, Iowa • North Canton, Ohio • Youngstown, Ohio",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "North Canton",
          "state": "Ohio"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01940744"
    },
    {
      "nct_id": "NCT02945943",
      "title": "Effects of Mobilization in Conjunction With Therapeutic Exercise in Participants With a History of Ankle Sprain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Functional Deficits",
        "Manipulation",
        "Rehabilitation"
      ],
      "interventions": [
        {
          "name": "High Velocity Low Amplitude mobilization",
          "type": "OTHER"
        },
        {
          "name": "Exercise Protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "16 Years to 35 Years"
      },
      "enrollment_count": 19,
      "start_date": "2012-02",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2016-10-26",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Winchester, Virginia",
      "locations": [
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02945943"
    },
    {
      "nct_id": "NCT02848456",
      "title": "The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subluxation of Joint of Lumbar Spine"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Max Voluntary Isometric Contraction",
          "type": "PROCEDURE"
        },
        {
          "name": "SM+MVIC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Grant Sanders",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "20 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2014-08",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2017-04-19",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02848456"
    },
    {
      "nct_id": "NCT01689168",
      "title": "Chiropractic Treatment With Counseling Versus Counseling Alone for Promoting Smoking Cessation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Chiropractic adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Southern California University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2012-03",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-05-20",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Whittier, California",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01689168"
    },
    {
      "nct_id": "NCT04513535",
      "title": "Effects of Manual Therapy on Shoulder Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Manipulations",
        "Shoulder",
        "Range of Motion",
        "Muscle Strength",
        "Surface Electromyography"
      ],
      "interventions": [
        {
          "name": "Thoracic Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Cervical Manipulation",
          "type": "OTHER"
        },
        {
          "name": "glenohumeral posterior glide mobilization",
          "type": "OTHER"
        },
        {
          "name": "Sleeper stretch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 48,
      "start_date": "2020-02-07",
      "completion_date": "2020-11-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-23",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513535"
    },
    {
      "nct_id": "NCT00830596",
      "title": "Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        },
        {
          "name": "LVVA-SM",
          "type": "OTHER"
        },
        {
          "name": "Sham Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 221,
      "start_date": "2007-07",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-10-11T20:06:50.633Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830596"
    }
  ]
}