{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=History&page=3",
    "query": {
      "intervention": "History",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 4104,
    "total_pages": 411,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=History&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=History&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-18T07:58:13.763Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01778543",
      "title": "Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coloboma",
        "Anophthalmia",
        "Microphthalmia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "1 Year to 100 Years"
      },
      "enrollment_count": 600,
      "start_date": "2013-01-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-10-16",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01778543"
    },
    {
      "nct_id": "NCT01963650",
      "title": "Natural History Study of Children With Metachromatic Leukodystrophy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lipid Metabolism Disorders",
        "Metachromatic Leukodystrophy (MLD)",
        "Nervous System Diseases",
        "Brain Diseases",
        "Central Nervous System Diseases",
        "Demyelinating Diseases",
        "Metabolism, Inborn Errors",
        "Genetic Diseases, Inborn",
        "Sphingolipidoses",
        "Hereditary Central Nervous System Demyelinating Diseases",
        "Metabolic Inborn Brain Diseases",
        "Lysosomal Storage Diseases",
        "Metabolic Diseases",
        "Sulfatidosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Shire",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "Up to 12 Years"
      },
      "enrollment_count": 1,
      "start_date": "2015-11-02",
      "completion_date": "2016-04-08",
      "has_results": false,
      "last_update_posted_date": "2021-03-17",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 4,
      "location_summary": "Torrance, California • Washington D.C., District of Columbia • Chicago, Illinois + 1 more",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01963650"
    },
    {
      "nct_id": "NCT04442425",
      "title": "Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer",
        "Neoplasms",
        "Solid Tumors"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "12 Years to 120 Years"
      },
      "enrollment_count": 83,
      "start_date": "2020-10-27",
      "completion_date": "2024-03-27",
      "has_results": false,
      "last_update_posted_date": "2026-10-16",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04442425"
    },
    {
      "nct_id": "NCT02107976",
      "title": "Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Type 2"
      ],
      "interventions": [
        {
          "name": "Vitamin E",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Vitamin C",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 28,
      "start_date": "2019-06-14",
      "completion_date": "2025-03-05",
      "has_results": true,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02107976"
    },
    {
      "nct_id": "NCT02431923",
      "title": "Ebola Virus Disease Survivors: Clinical and Immunologic Follow-up",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ebola Virus Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "Up to 100 Years"
      },
      "enrollment_count": 4043,
      "start_date": "2017-12-02",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2022-10-10",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02431923"
    },
    {
      "nct_id": "NCT01132859",
      "title": "VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Immunity, Mucosal",
        "Immune System Processes",
        "Blood Specimen Collection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "18 Years to 120 Years"
      },
      "enrollment_count": 500,
      "start_date": "2010-05-18",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-10-16",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01132859"
    },
    {
      "nct_id": "NCT00983879",
      "title": "The Natural History of Infantile Globoid Cell Leukodystrophy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infantile Globoid Cell Leukodystrophy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Zymenex A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 6,
      "start_date": "2009-09",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2018-03-08",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00983879"
    },
    {
      "nct_id": "NCT03626246",
      "title": "Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Kidney Disease",
        "End Stage Kidney Disease",
        "Chronic Kidney Disease Mineral and Bone Disorder",
        "Renal Osteodystrophy",
        "Secondary Hyperparathyroidism"
      ],
      "interventions": [
        {
          "name": "Kidney disease",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2016-07-01",
      "completion_date": "2020-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-07-13",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03626246"
    },
    {
      "nct_id": "NCT07757490",
      "title": "Sonablate HIFU International Registry for PC & BPH Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Localized Prostate Cancer",
        "BPH (Benign Prostatic Hyperplasia)",
        "Prostate Cancer; Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "High Intensity Focused Ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sonablate",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 10000,
      "start_date": "2015-01-01",
      "completion_date": "2035-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07757490"
    },
    {
      "nct_id": "NCT00985413",
      "title": "Observational Study to Assess Natural History in Cockayne Syndrome Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cockayne Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "DNage B.V.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "1 Year to 11 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-09",
      "completion_date": "2011-02",
      "has_results": false,
      "last_update_posted_date": "2011-06-23",
      "last_synced_at": "2026-10-18T07:58:13.763Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • New York, New York",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00985413"
    }
  ]
}