{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hormone+Replacement+Therapy+-+HRT&page=2",
    "query": {
      "intervention": "Hormone Replacement Therapy - HRT",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 147,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hormone+Replacement+Therapy+-+HRT&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hormone+Replacement+Therapy+-+HRT&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T11:26:49.328Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07848438",
      "title": "Sex Hormones and Aging",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Menopausal Hormone Therapy",
        "Aging"
      ],
      "interventions": [
        {
          "name": "HRT: High-Resistance Strength Training",
          "type": "OTHER"
        },
        {
          "name": "Control: High-Resistance Strength Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "50 Years to 70 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2026-08-20",
      "completion_date": "2031-08",
      "has_results": false,
      "last_update_posted_date": "2026-09-30",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07848438"
    },
    {
      "nct_id": "NCT07742553",
      "title": "Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Spinal Cord Injury",
        "Spinal Cord Injuries",
        "Injuries, Spinal Cord",
        "Spinal Cord Contusion",
        "Spinal Cord Trauma",
        "Trauma, Nervous System",
        "Wounds and Injuries",
        "Spinal Cord Compression",
        "Nervous System Diseases",
        "Spinal Cord Diseases",
        "Gonadal Disorders",
        "Endocrine System Diseases",
        "Hypogonadism",
        "Genital Diseases, Male"
      ],
      "interventions": [
        {
          "name": "testosterone cypionate",
          "type": "DRUG"
        },
        {
          "name": "finasteride",
          "type": "DRUG"
        },
        {
          "name": "placebo injection",
          "type": "DRUG"
        },
        {
          "name": "placebo pill",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 300,
      "start_date": "2027-10-01",
      "completion_date": "2032-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-04",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 4,
      "location_summary": "Aurora, Colorado • Gainesville, Florida • Tampa, Florida + 1 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07742553"
    },
    {
      "nct_id": "NCT03134976",
      "title": "Wound Complications in Head and Neck Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypothyroidism; Surgery",
        "Head and Neck Cancer",
        "Wound Heal",
        "Laryngeal Cancer",
        "Laryngeal Fistula"
      ],
      "interventions": [
        {
          "name": "Levothyroxine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2017-05-01",
      "completion_date": "2020-05-01",
      "has_results": false,
      "last_update_posted_date": "2020-06-01",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03134976"
    },
    {
      "nct_id": "NCT00801632",
      "title": "Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Kidney Transplantation",
        "Kidney Failure, Chronic"
      ],
      "interventions": [
        {
          "name": "Kidney Transplantation",
          "type": "PROCEDURE"
        },
        {
          "name": "Bone marrow transplantation",
          "type": "PROCEDURE"
        },
        {
          "name": "MEDI-507",
          "type": "BIOLOGICAL"
        },
        {
          "name": "cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "rituximab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tacrolimus",
          "type": "DRUG"
        },
        {
          "name": "corticosteroids",
          "type": "DRUG"
        },
        {
          "name": "thymic irradiation",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL",
        "DRUG",
        "RADIATION"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 5,
      "start_date": "2008-12",
      "completion_date": "2014-11",
      "has_results": true,
      "last_update_posted_date": "2015-11-10",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00801632"
    },
    {
      "nct_id": "NCT00131378",
      "title": "Growth Hormone, Cardiovascular Risk, and Visceral Adiposity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Nutropin AQ growth hormone",
          "type": "DRUG"
        },
        {
          "name": "Placebo Growth Hormone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 142,
      "start_date": "2004-11",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2016-03-11",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00131378"
    },
    {
      "nct_id": "NCT00001770",
      "title": "Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depressive Disorder",
        "Mood Disorder",
        "Psychomotor Agitation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 50,
      "start_date": "1998-03",
      "completion_date": "2003-03",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001770"
    },
    {
      "nct_id": "NCT00957671",
      "title": "Anterior Pituitary Hormone Replacement in Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Growth Hormone Deficiency",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Recombinant human growth hormone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2003-11",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2018-06-29",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 2,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        },
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00957671"
    },
    {
      "nct_id": "NCT06472765",
      "title": "Vaginal Ecosystem and Network in the United States Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bacterial Vaginosis",
        "Candidiasis",
        "Urinary Tract Infections",
        "Genitourinary Syndrome of Menopause",
        "Lichen Sclerosus",
        "Lichen Planus",
        "Vulvodynia",
        "Endometriosis",
        "Ureaplasma Infections",
        "Cancer",
        "Desquamative Inflammatory Vaginitis"
      ],
      "interventions": [
        {
          "name": "Vaginal Swab Collection",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vaginal Biome Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 89 Years · Female only"
      },
      "enrollment_count": 3250,
      "start_date": "2024-05-16",
      "completion_date": "2028-05-15",
      "has_results": false,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 20,
      "location_summary": "Fullerton, California • Los Angeles, California • Pasadena, California + 16 more",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06472765"
    },
    {
      "nct_id": "NCT00276081",
      "title": "Gabapentin Versus Estrogen for the Treatment of Hot Flashes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "Gabapentin, Estrogen and placebo administration",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2002-05",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2006-11-28",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00276081"
    },
    {
      "nct_id": "NCT07278323",
      "title": "Frozen Shoulder and Hormone Replacement Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Adhesive Capsulitis of the Shoulder",
        "Frozen Shoulder"
      ],
      "interventions": [
        {
          "name": "Hormone Replacement Therapy (HRT)",
          "type": "DRUG"
        },
        {
          "name": "Corticosteroid and 1%lidocain",
          "type": "DRUG"
        },
        {
          "name": "physical therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2026-01-15",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-10-04T11:26:49.328Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07278323"
    }
  ]
}