{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Humidified+Nasal+High+Flow+Therapy",
    "query": {
      "intervention": "Humidified Nasal High Flow Therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Humidified+Nasal+High+Flow+Therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T18:01:32.097Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03086265",
      "title": "Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Otorhinolaryngologic Surgical Procedures",
        "Laser Therapy"
      ],
      "interventions": [
        {
          "name": "THRIVE",
          "type": "DEVICE"
        },
        {
          "name": "Endotracheal tube",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-03-24",
      "completion_date": "2019-02-26",
      "has_results": true,
      "last_update_posted_date": "2020-03-17",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03086265"
    },
    {
      "nct_id": "NCT04322994",
      "title": "THRIVE Use in Pediatric Populations- Multi Site",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oxygen Deficiency",
        "Desaturation of Blood",
        "Hypoventilation",
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Transnasal Humidified Rapid-Insufflation Ventilatory Echange",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 175,
      "start_date": "2020-10-21",
      "completion_date": "2024-01-19",
      "has_results": true,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 5,
      "location_summary": "Palo Alto, California • Chicago, Illinois • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04322994"
    },
    {
      "nct_id": "NCT03024112",
      "title": "Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Pulmonary Complications"
      ],
      "interventions": [
        {
          "name": "Heated humified high-flow nasal cannula Oxygen",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 51,
      "start_date": "2013-08",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03024112"
    },
    {
      "nct_id": "NCT02514798",
      "title": "Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD"
      ],
      "interventions": [
        {
          "name": "Esophageal and gastric balloons",
          "type": "OTHER"
        },
        {
          "name": "Respiratory Inductance Plethysmography (RIP) system",
          "type": "OTHER"
        },
        {
          "name": "Sentec transcutaneous monitoring system",
          "type": "OTHER"
        },
        {
          "name": "High-flow humidified nasal oxygen delivery system",
          "type": "DEVICE"
        },
        {
          "name": "CPAP (Positive Control)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2015-07",
      "completion_date": "2018-04-01",
      "has_results": false,
      "last_update_posted_date": "2022-05-10",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02514798"
    },
    {
      "nct_id": "NCT00990119",
      "title": "High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Vapotherm High Flow Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Non-invasive positive pressure ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2009-09",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00990119"
    },
    {
      "nct_id": "NCT01925534",
      "title": "Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure",
        "Treatment With Noninvasive Positive Pressure Ventilation"
      ],
      "interventions": [
        {
          "name": "High-flow humidified nasal oxygen delivery system",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2013-11",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Winchester, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Winchester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01925534"
    },
    {
      "nct_id": "NCT06610461",
      "title": "High-flow Nasal Oxygen Therapy for Advanced Endoscopy in High-risk Patients.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemia During Surgery"
      ],
      "interventions": [
        {
          "name": "HFNO-Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2024-09-25",
      "completion_date": "2025-09-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06610461"
    },
    {
      "nct_id": "NCT03221387",
      "title": "Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Hypercapnia",
        "Hypoxia"
      ],
      "interventions": [
        {
          "name": "Humidified nasal high flow with oxygen",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Temple University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-09-10",
      "completion_date": "2019-12-15",
      "has_results": true,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03221387"
    },
    {
      "nct_id": "NCT01939067",
      "title": "Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Respiratory Distress",
        "Lung Injury"
      ],
      "interventions": [
        {
          "name": "Heated Humidified High Flow Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Continuous Positive Airway Pressure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "2 Hours to 72 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-09-15",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939067"
    },
    {
      "nct_id": "NCT03086408",
      "title": "Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Diagnostic Bronchoscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchoscopy"
      ],
      "interventions": [
        {
          "name": "THRIVE",
          "type": "DEVICE"
        },
        {
          "name": "Endotracheal tube or Supraglottic airway",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-05-09",
      "completion_date": "2019-06-10",
      "has_results": true,
      "last_update_posted_date": "2020-07-17",
      "last_synced_at": "2026-09-25T18:01:32.097Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03086408"
    }
  ]
}