{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hyperpolarized+Xenon+-129+MRI", "query": { "intervention": "Hyperpolarized Xenon -129 MRI" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 39, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hyperpolarized+Xenon+-129+MRI&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-29T23:06:03.640Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06012500", "title": "Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "ILD" ], "interventions": [ { "name": "Xenon-129", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 78, "start_date": "2022-04-14", "completion_date": "2027-12-30", "has_results": false, "last_update_posted_date": "2026-02-13", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06012500" }, { "nct_id": "NCT02826343", "title": "New Technology to Assess Treatment for Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Xenon129 MRI imaging", "type": "DRUG" }, { "name": "Gadolinium MRI", "type": "DRUG" }, { "name": "Advair (250mcg/50mcg) one puff twice a day", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 30, "start_date": "2016-05-01", "completion_date": "2018-06-15", "has_results": false, "last_update_posted_date": "2020-11-04", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Charlottesville, Virginia", "locations": [ { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02826343" }, { "nct_id": "NCT05241275", "title": "Xenon MRI and Progressive ILD", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Idiopathic Pulmonary Fibrosis", "Progressive Pulmonary Fibrosis" ], "interventions": [ { "name": "Hyperpolarized 129 Xenon Gas Comparing Progressive Pulmonary Fibrosis Treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2022-07-19", "completion_date": "2026-08-31", "has_results": false, "last_update_posted_date": "2026-06-11", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05241275" }, { "nct_id": "NCT04071769", "title": "Genentech Xenon MRI Idiopathic Pulmonary Fibrosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Idiopathic Pulmonary Fibrosis" ], "interventions": [ { "name": "Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 34, "start_date": "2020-08-03", "completion_date": "2025-10-17", "has_results": true, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04071769" }, { "nct_id": "NCT06985225", "title": "Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Severe Asthma", "COPD", "Non-CF Bronchiectasis", "Cystic Fibrosis (CF)" ], "interventions": [ { "name": "Hyperpolarized 129 Xenon", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 8, "start_date": "2025-06-01", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-07-01", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Kansas City, Kansas", "locations": [ { "city": "Kansas City", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06985225" }, { "nct_id": "NCT05302817", "title": "Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Carcinoma, Non-Small-Cell Lung" ], "interventions": [ { "name": "Hyperpolarized xenon MRI", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Xemed LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 9, "start_date": "2023-03-17", "completion_date": "2025-02-28", "has_results": false, "last_update_posted_date": "2026-01-20", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05302817" }, { "nct_id": "NCT02272049", "title": "Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Respiratory Disorders" ], "interventions": [ { "name": "Hyperpolarized 129 Xenon", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 300, "start_date": "2014-12", "completion_date": "2029-08-31", "has_results": false, "last_update_posted_date": "2026-02-17", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02272049" }, { "nct_id": "NCT06038630", "title": "129Xe MRI Cardiopulmonary", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Interstitial Lung Disease", "Chronic Thromboembolic Pulmonary Hypertension", "Acute Pulmonary Embolism", "Anemia", "Polycythemia", "Dyspnea" ], "interventions": [ { "name": "Hyperpolarized Xe129", "type": "DRUG" }, { "name": "Oxygen Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Bastiaan Driehuys", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 125, "start_date": "2024-01-12", "completion_date": "2028-06-30", "has_results": false, "last_update_posted_date": "2026-02-04", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06038630" }, { "nct_id": "NCT06909201", "title": "Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Cancer" ], "interventions": [ { "name": "HP 129Xe MRI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2026-03-31", "completion_date": "2030-09-01", "has_results": false, "last_update_posted_date": "2026-08-25", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06909201" }, { "nct_id": "NCT06104228", "title": "129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension", "Idiopathic Pulmonary Arterial Hypertension", "Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)", "Connective Tissue Diseases" ], "interventions": [ { "name": "129Xe Hyperpolarized", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bastiaan Driehuys", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 20, "start_date": "2024-08-12", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-02-24", "last_synced_at": "2026-09-29T23:06:03.640Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06104228" } ] }