{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hypoxic+breathing+conditions",
    "query": {
      "intervention": "Hypoxic breathing conditions"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Hypoxic+breathing+conditions&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T01:10:39.145Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03736382",
      "title": "Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Mild intermittent hypoxia",
          "type": "OTHER"
        },
        {
          "name": "Sham protocol",
          "type": "OTHER"
        },
        {
          "name": "Continuous positive airway pressure (CPAP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 47,
      "start_date": "2018-11-15",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 2,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03736382"
    },
    {
      "nct_id": "NCT05558501",
      "title": "Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Mild Intermittent Hypoxia",
          "type": "OTHER"
        },
        {
          "name": "Sham MIH",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-01-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-04",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05558501"
    },
    {
      "nct_id": "NCT05168501",
      "title": "Assessing Variability of the Ventilatory Response to Duffin's Rebreathing Procedure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilation",
        "Reproducibility",
        "Physiology"
      ],
      "interventions": [
        {
          "name": "Rebreathing procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Food and Drug Administration (FDA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 7,
      "start_date": "2021-12-27",
      "completion_date": "2022-02-18",
      "has_results": true,
      "last_update_posted_date": "2024-07-15",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "West Bend, Wisconsin",
      "locations": [
        {
          "city": "West Bend",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05168501"
    },
    {
      "nct_id": "NCT04559763",
      "title": "SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxia",
        "Desaturation of Blood"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Controlled Hypoxia",
          "type": "DEVICE"
        },
        {
          "name": "Introduction of Motion conditions: tapping or rubbing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 16,
      "start_date": "2020-08-18",
      "completion_date": "2020-08-21",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Louisville, Colorado",
      "locations": [
        {
          "city": "Louisville",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04559763"
    },
    {
      "nct_id": "NCT05463042",
      "title": "Intermittent Hypoxia and Balance Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intermittent Hypoxia",
        "Normoxia"
      ],
      "interventions": [
        {
          "name": "Intermittent Hypoxia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normoxia (sham)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 3,
      "start_date": "2022-09-01",
      "completion_date": "2023-08-21",
      "has_results": false,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05463042"
    },
    {
      "nct_id": "NCT02482571",
      "title": "Metabolic Changes in the Activated Human Visual Cortex During Mild Hypoxia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Hypoxia"
      ],
      "interventions": [
        {
          "name": "Mild Hypoxia",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 25,
      "start_date": "2015-08-13",
      "completion_date": "2016-09-26",
      "has_results": true,
      "last_update_posted_date": "2019-03-19",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02482571"
    },
    {
      "nct_id": "NCT07027150",
      "title": "Pulse Oximeter Validation Study for the Perin Health Patch",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxia"
      ],
      "interventions": [
        {
          "name": "Chest Worn Pulse Oximeter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Perin Health Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 12,
      "start_date": "2025-05-27",
      "completion_date": "2025-05-28",
      "has_results": false,
      "last_update_posted_date": "2025-06-18",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07027150"
    },
    {
      "nct_id": "NCT06614309",
      "title": "Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Long COVID"
      ],
      "interventions": [
        {
          "name": "Acute Placebo Visit",
          "type": "OTHER"
        },
        {
          "name": "Acute Progressive Carbon Dioxide",
          "type": "OTHER"
        },
        {
          "name": "Acute Intermittent Hypoxia",
          "type": "OTHER"
        },
        {
          "name": "Training: Progressive Carbon Dioxide Ramping",
          "type": "OTHER"
        },
        {
          "name": "Training: Intermittent Hypoxic Exposure",
          "type": "OTHER"
        },
        {
          "name": "Training: Placebo Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2024-09-24",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06614309"
    },
    {
      "nct_id": "NCT03143920",
      "title": "Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Chronic Interstitial Cystitis",
        "Painful Bladder Syndrome",
        "Recurrent Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen Therapy-",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 70 Years · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2017-11-01",
      "completion_date": "2022-07-07",
      "has_results": false,
      "last_update_posted_date": "2022-07-11",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03143920"
    },
    {
      "nct_id": "NCT07216755",
      "title": "Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adults",
        "Mechanical Ventilation Dependence",
        "Hypoxia",
        "Exercise Training",
        "Exercise Intolerance",
        "Dietary Supplement",
        "Nitrate Supplementation",
        "Inspiratory Muscle Training"
      ],
      "interventions": [
        {
          "name": "Respiratory Muscle Training (RMT)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Respiratory Muscle Training",
          "type": "DEVICE"
        },
        {
          "name": "Dietary Supplement: Beetroot Juice Concentrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "placebo beverage",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Embry-Riddle Aeronautical University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-09-01",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-27T01:10:39.145Z",
      "location_count": 1,
      "location_summary": "Daytona Beach, Florida",
      "locations": [
        {
          "city": "Daytona Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07216755"
    }
  ]
}