{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IBU+BID", "query": { "intervention": "IBU BID" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 23, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IBU+BID&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T05:41:36.426Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05488847", "title": "Opioid-Free Pain Protocol After Shoulder Arthroplasty", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Shoulder Arthropathy", "Shoulder Pain" ], "interventions": [ { "name": "Celecoxib", "type": "DRUG" }, { "name": "Pregabalin", "type": "DRUG" }, { "name": "Tramadol", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Ropivicaine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Ketorolac", "type": "DRUG" }, { "name": "Tizanidine", "type": "DRUG" }, { "name": "Magnesium", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Oxycodone Hydrochloride 5 Mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Henry Ford Health System", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2022-06-25", "completion_date": "2026-09-01", "has_results": true, "last_update_posted_date": "2026-02-10", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT05488847" }, { "nct_id": "NCT07600697", "title": "Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pelvic Organ Prolapse (POP)", "Stress Urinary Incontinence (SUI)", "Postoperative Pain" ], "interventions": [ { "name": "Suzetrigine", "type": "DRUG" }, { "name": "Opioid Analgesics (Tramadol or Oxycodone)", "type": "DRUG" }, { "name": "Scheduled Acetaminophen and Ibuprofen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 120, "start_date": "2026-07-01", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07600697" }, { "nct_id": "NCT00662896", "title": "To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Osteoarthritis", "Hypertension" ], "interventions": [ { "name": "naproxcinod 375 mg bid", "type": "DRUG" }, { "name": "naproxcinod 750 mg bid", "type": "DRUG" }, { "name": "naproxen 250 mg bid", "type": "DRUG" }, { "name": "naproxen 500 mg bid", "type": "DRUG" }, { "name": "ibuprofen 600 mg tid", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NicOx", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 300, "start_date": "2008-03", "completion_date": "2008-12", "has_results": false, "last_update_posted_date": "2011-06-17", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 57, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Sierra Vista, Arizona + 54 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Carmichael", "state": "California" }, { "city": "Fair Oaks", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00662896" }, { "nct_id": "NCT04220892", "title": "Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "High Grade Glioma" ], "interventions": [ { "name": "Pembrolizumab", "type": "DRUG" }, { "name": "Pemetrexed", "type": "DRUG" }, { "name": "Abemaciclib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jose Carrillo", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2020-07-08", "completion_date": "2020-07-08", "has_results": false, "last_update_posted_date": "2020-07-31", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Santa Monica, California", "locations": [ { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04220892" }, { "nct_id": "NCT00346216", "title": "Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Arthritis, Rheumatoid" ], "interventions": [ { "name": "celecoxib", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Naproxen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer's Upjohn has merged with Mylan to form Viatris Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24081, "start_date": "2006-10-04", "completion_date": "2016-04-12", "has_results": true, "last_update_posted_date": "2021-03-03", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 871, "location_summary": "Alabaster, Alabama • Bessemer, Alabama • Birmingham, Alabama + 515 more", "locations": [ { "city": "Alabaster", "state": "Alabama" }, { "city": "Bessemer", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00346216" }, { "nct_id": "NCT00640809", "title": "Comparison of Small Bowel Lesions Associated With Celecoxib Versus Ibuprofen Plus Omeprazole", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bowel Diseases, Inflammatory" ], "interventions": [ { "name": "Celecoxib", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Ibuprofen plus Omeprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Pfizer's Upjohn has merged with Mylan to form Viatris Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 408, "start_date": "2003-10", "completion_date": "2004-04", "has_results": false, "last_update_posted_date": "2021-02-02", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 12, "location_summary": "Scottsdale, Arizona • La Jolla, California • Los Angeles, California + 8 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Jupiter", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00640809" }, { "nct_id": "NCT03186638", "title": "Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cognitive Impairment", "Malignant Neoplasm" ], "interventions": [ { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Rochester NCORP Research Base", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 87, "start_date": "2017-05-26", "completion_date": "2022-06-01", "has_results": true, "last_update_posted_date": "2023-09-25", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 169, "location_summary": "Burbank, California • Lewes, Delaware • Newark, Delaware + 99 more", "locations": [ { "city": "Burbank", "state": "California" }, { "city": "Lewes", "state": "Delaware" }, { "city": "Newark", "state": "Delaware" }, { "city": "Newark", "state": "Delaware" }, { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT03186638" }, { "nct_id": "NCT00707057", "title": "Ibuprofen Extended-Release Dental Pain Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Post-Operative Pain", "Third Molar Extraction" ], "interventions": [ { "name": "Ibuprofen 600 mg Extended-Release Tablets", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "SCOLR Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "16 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "16 Years to 45 Years" }, "enrollment_count": 256, "start_date": "2008-06", "completion_date": "2008-10", "has_results": true, "last_update_posted_date": "2011-03-24", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00707057" }, { "nct_id": "NCT02986334", "title": "Placebo In Chronic Back Pain (Phase 2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Chronic Low Back Pain" ], "interventions": [ { "name": "Naproxen", "type": "DRUG" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Apkar Apkarian", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 94, "start_date": "2016-08", "completion_date": "2018-06", "has_results": true, "last_update_posted_date": "2022-11-07", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02986334" }, { "nct_id": "NCT04990804", "title": "Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Opioid Use", "Spinal Diseases", "Surgery--Complications", "Surgery", "Postoperative Pain" ], "interventions": [ { "name": "Opioid Analgesic", "type": "DRUG" }, { "name": "Opioid-Free Postoperative Pain Regimen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2021-08-01", "completion_date": "2022-02-01", "has_results": true, "last_update_posted_date": "2024-01-31", "last_synced_at": "2026-09-15T05:41:36.426Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04990804" } ] }