{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ICS%2FLABA+therapy&page=2", "query": { "intervention": "ICS/LABA therapy", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ICS%2FLABA+therapy&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-25T06:54:04.597Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03387852", "title": "Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "SAR440340", "type": "DRUG" }, { "name": "Dupilumab", "type": "DRUG" }, { "name": "Fluticasone or Fluticasone/salmeterol combination", "type": "DRUG" }, { "name": "Placebo for SAR440340", "type": "DRUG" }, { "name": "Placebo for dupilumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 296, "start_date": "2018-03-12", "completion_date": "2019-08-07", "has_results": true, "last_update_posted_date": "2022-06-14", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Long Beach, California • Los Angeles, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Jose", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03387852" }, { "nct_id": "NCT04072887", "title": "Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "QBW251", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "COPD maintenance background therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 974, "start_date": "2019-09-12", "completion_date": "2022-02-01", "has_results": true, "last_update_posted_date": "2023-04-28", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 25, "location_summary": "Andalusia, Alabama • Los Angeles, California • Westminster, California + 22 more", "locations": [ { "city": "Andalusia", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Westminster", "state": "California" }, { "city": "Ormond Beach", "state": "Florida" }, { "city": "Sarasota", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04072887" }, { "nct_id": "NCT02175771", "title": "Long-Term Safety Study of Fluticasone Propionate (Fp) Multidose Dry Powder Inhaler (MDPI) and Fluticasone Propionate/Salmeterol (FS) MDPI in Patients With Persistent Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Persistent Asthma" ], "interventions": [ { "name": "Fp MDPI", "type": "DRUG" }, { "name": "FS MDPI", "type": "DRUG" }, { "name": "FLOVENT HFA", "type": "DRUG" }, { "name": "ADVAIR DISKUS", "type": "DRUG" }, { "name": "albuterol/salbutamol HFA", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 758, "start_date": "2014-07", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2021-11-09", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 101, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Pell City, Alabama + 85 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Pell City", "state": "Alabama" }, { "city": "Little Rock", "state": "Alaska" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02175771" }, { "nct_id": "NCT03949842", "title": "Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Inhaled corticosteroids/long-acting beta2-adrenergic/long-acting muscarinic receptor antagonists", "type": "DRUG" }, { "name": "Fluticasone furoate/umeclidinium/vilanterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 0, "start_date": "2019-06-27", "completion_date": "2022-11-30", "has_results": false, "last_update_posted_date": "2020-04-22", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 3, "location_summary": "Waterbury, Connecticut • Charlotte, North Carolina • Layton, Utah", "locations": [ { "city": "Waterbury", "state": "Connecticut" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Layton", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03949842" }, { "nct_id": "NCT01854047", "title": "An Evaluation of Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Dupilumab", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "ICS/LABA therapy", "type": "DRUG" }, { "name": "Salbutamol/albuterol", "type": "DRUG" }, { "name": "Levosalbutamol/levalbuterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 776, "start_date": "2013-06", "completion_date": "2015-04", "has_results": true, "last_update_posted_date": "2017-06-26", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 50, "location_summary": "Fullerton, California • Huntington Beach, California • Los Angeles, California + 38 more", "locations": [ { "city": "Fullerton", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01854047" }, { "nct_id": "NCT04184297", "title": "Comparative Effectiveness and Safety of Tiotropium and Olodaterol in Comparison to Triple Therapy", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Tiotropium and Olodaterol (Tio+Olo)", "type": "DRUG" }, { "name": "Long-acting beta2-agonist and Inhaled corticosteroids (LABA and ICS)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 27190, "start_date": "2019-11-01", "completion_date": "2019-11-04", "has_results": true, "last_update_posted_date": "2021-11-15", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 1, "location_summary": "Andover, Massachusetts", "locations": [ { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04184297" }, { "nct_id": "NCT03219866", "title": "Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "COPD", "COPD Exacerbation" ], "interventions": [ { "name": "Nebulizers", "type": "DEVICE" }, { "name": "Dry Powder Inhaler", "type": "DEVICE" }, { "name": "Brovana", "type": "DRUG" }, { "name": "Pulmicort", "type": "DRUG" }, { "name": "Atrovent", "type": "DRUG" }, { "name": "Advair Diskus", "type": "DRUG" }, { "name": "Spiriva HandiHaler", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 40, "start_date": "2017-10-03", "completion_date": "2020-04-01", "has_results": true, "last_update_posted_date": "2021-06-22", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03219866" }, { "nct_id": "NCT07051707", "title": "Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "COPD", "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Targeted Lung Denervation (TLD)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Nuvaira, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 200, "start_date": "2026-02-24", "completion_date": "2029-10-31", "has_results": false, "last_update_posted_date": "2026-04-28", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 10, "location_summary": "Birmingham, Alabama • Jacksonville, Florida • Detroit, Michigan + 7 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Salem", "state": "North Carolina" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07051707" }, { "nct_id": "NCT02573233", "title": "Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Dupilumab SAR231893/REGN668", "type": "DRUG" }, { "name": "fluticasone propionate and salmeterol", "type": "DRUG" }, { "name": "budesonide and formoterol", "type": "DRUG" }, { "name": "mometasone furoate and formoterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 42, "start_date": "2016-01-27", "completion_date": "2018-01-03", "has_results": true, "last_update_posted_date": "2022-04-04", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 6, "location_summary": "Tucson, Arizona • Denver, Colorado • Boston, Massachusetts + 3 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Denver", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02573233" }, { "nct_id": "NCT04053634", "title": "Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Benralizumab", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "40 Years to 85 Years" }, "enrollment_count": 689, "start_date": "2019-08-26", "completion_date": "2025-07-28", "has_results": false, "last_update_posted_date": "2025-08-19", "last_synced_at": "2026-09-25T06:54:04.597Z", "location_count": 84, "location_summary": "Surprise, Arizona • Little Rock, Arkansas • Los Angeles, California + 77 more", "locations": [ { "city": "Surprise", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04053634" } ] }