{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ICSI&page=2",
    "query": {
      "intervention": "ICSI",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ICSI&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T05:38:10.021Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06990906",
      "title": "Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Male Infertility, Azoospermia"
      ],
      "interventions": [
        {
          "name": "BAIBYS Sperm selection",
          "type": "DEVICE"
        },
        {
          "name": "Intra cytoplasmatic sperm injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional manual sperm selection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "BAIBYS Fertility",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "42 Years",
        "sex": "ALL",
        "summary": "21 Years to 42 Years"
      },
      "enrollment_count": 260,
      "start_date": "2026-03-15",
      "completion_date": "2026-10-15",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "Stamford, Connecticut",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06990906"
    },
    {
      "nct_id": "NCT05633316",
      "title": "Automated Intracytoplasmic Sperm Injection (ICSIA)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility, Female"
      ],
      "interventions": [
        {
          "name": "Investigational device named ICSIA",
          "type": "DEVICE"
        },
        {
          "name": "Manual ICSI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Overture Life",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2022-12-05",
      "completion_date": "2024-11-30",
      "has_results": false,
      "last_update_posted_date": "2023-07-06",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05633316"
    },
    {
      "nct_id": "NCT03483298",
      "title": "Split Cohort Trial Comparing IVF Outcomes After the Use of Testicular vs. Ejaculated Sperm for ICSI",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "ICSI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Reproductive Medicine Associates of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "18 Years to 65 Years · Male only"
      },
      "enrollment_count": 7,
      "start_date": "2018-06-23",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "Basking Ridge, New Jersey",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03483298"
    },
    {
      "nct_id": "NCT02865681",
      "title": "Protocol to Minimize Injections and Blood Draws for Women Undergoing in Vitro Fertilization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Menopur",
          "type": "DRUG"
        },
        {
          "name": "Synarel",
          "type": "DRUG"
        },
        {
          "name": "HCG trigger",
          "type": "DRUG"
        },
        {
          "name": "Clomiphene citrate",
          "type": "DRUG"
        },
        {
          "name": "Letrozole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New Hope Fertility Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2016-07-01",
      "completion_date": "2017-06-07",
      "has_results": false,
      "last_update_posted_date": "2019-03-19",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02865681"
    },
    {
      "nct_id": "NCT02357654",
      "title": "GnRH for Luteal Support in IVF/ICSI/FET Cycles",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "GnRH",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University Reproductive Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 350,
      "start_date": "2015-11",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "Hasbrouck Heights, New Jersey",
      "locations": [
        {
          "city": "Hasbrouck Heights",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02357654"
    },
    {
      "nct_id": "NCT00708383",
      "title": "in Vitro Fertilization (IVF) Media Protein and Live Birth Rates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility",
        "Pregnancy Outcome, Live Birth",
        "In Vitro Fertilization"
      ],
      "interventions": [
        {
          "name": "10% SSS embryo culture medium protein supplementation",
          "type": "OTHER"
        },
        {
          "name": "0.5% HSA embryo culture medium protein supplementation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Health Resources",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 40 Years · Female only"
      },
      "enrollment_count": 538,
      "start_date": "2001-09",
      "completion_date": "2003-11",
      "has_results": false,
      "last_update_posted_date": "2008-07-02",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Plano, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00708383"
    },
    {
      "nct_id": "NCT04246268",
      "title": "Assessment of the INVOcell Intravaginal Culture System",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "INVOcell",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "INVO Bioscience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "37 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 37 Years · Female only"
      },
      "enrollment_count": 180,
      "start_date": "2020-10",
      "completion_date": "2022-03",
      "has_results": false,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 4,
      "location_summary": "Greenville, South Carolina • West Columbia, South Carolina • San Antonio, Texas + 1 more",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        },
        {
          "city": "West Columbia",
          "state": "South Carolina"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Virginia Beach",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04246268"
    },
    {
      "nct_id": "NCT03085433",
      "title": "Sperm Selection by Microfluidic Separation Improves Embryo Quality",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sperm DNA Fragmentation",
        "Embryo Quality",
        "Fertility Disorders",
        "Infertility",
        "Infertility, Male",
        "Infertility Unexplained"
      ],
      "interventions": [
        {
          "name": "Microfluidic Sperm Sorting",
          "type": "DEVICE"
        },
        {
          "name": "in vitro fertilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 393,
      "start_date": "2017-06-20",
      "completion_date": "2022-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-12-31",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03085433"
    },
    {
      "nct_id": "NCT04878991",
      "title": "Overture Metabolomics Non-Selection Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Overture Metabolomics Embryo Selection",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Overture Life",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 410,
      "start_date": "2021-05-05",
      "completion_date": "2024-01-30",
      "has_results": false,
      "last_update_posted_date": "2023-11-14",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04878991"
    },
    {
      "nct_id": "NCT05859152",
      "title": "Zona Pellucida Bound Sperm vs. Embryologist Selected Sperm for Intracytoplasmic Sperm Injection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Zona Pellucida-Bound Sperm Selection for ICSI",
          "type": "OTHER"
        },
        {
          "name": "Routine Embryologist Selected Sperm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "IVI America",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "41 Years",
        "sex": "ALL",
        "summary": "18 Years to 41 Years"
      },
      "enrollment_count": 29,
      "start_date": "2023-11-03",
      "completion_date": "2025-09-14",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-09-15T05:38:10.021Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05859152"
    }
  ]
}