{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IL-6&page=2", "query": { "intervention": "IL-6", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IL-6&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-15T02:06:10.542Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00427973", "title": "AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Adult Primary Hepatocellular Carcinoma", "Advanced Adult Primary Liver Cancer", "Localized Unresectable Adult Primary Liver Cancer", "Recurrent Adult Primary Liver Cancer" ], "interventions": [ { "name": "cediranib maleate", "type": "DRUG" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "computed tomography", "type": "PROCEDURE" }, { "name": "dynamic contrast-enhanced magnetic resonance imaging", "type": "PROCEDURE" }, { "name": "pharmacological study", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 17, "start_date": "2009-05", "completion_date": "2012-03", "has_results": true, "last_update_posted_date": "2016-10-31", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00427973" }, { "nct_id": "NCT04381052", "title": "Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19" ], "interventions": [ { "name": "Clazakizumab", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2020-05-18", "completion_date": "2021-04-01", "has_results": true, "last_update_posted_date": "2022-04-08", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04381052" }, { "nct_id": "NCT05004389", "title": "Biomarkers of Independent Walking Post-Stroke", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Stroke, Acute", "Gait, Hemiplegic" ], "interventions": [ { "name": "MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "blood draw", "type": "DIAGNOSTIC_TEST" }, { "name": "Clinical assessments", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "OTHER" ], "sponsor": "University of Vermont", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2021-12-02", "completion_date": "2023-05", "has_results": false, "last_update_posted_date": "2023-03-14", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Burlington, Vermont", "locations": [ { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT05004389" }, { "nct_id": "NCT02253394", "title": "The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Ambrisentan plus Spironolactone", "type": "DRUG" }, { "name": "Ambrisentan plus Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2015-09", "completion_date": "2018-02", "has_results": true, "last_update_posted_date": "2019-11-15", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02253394" }, { "nct_id": "NCT06654895", "title": "Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Sepsis, Septic Shock" ], "interventions": [], "intervention_types": [], "sponsor": "Bluejay Diagnostics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 700, "start_date": "2024-11-12", "completion_date": "2026-09-30", "has_results": false, "last_update_posted_date": "2026-08-19", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 5, "location_summary": "Gainesville, Florida • Boston, Massachusetts • Winston-Salem, North Carolina + 2 more", "locations": [ { "city": "Gainesville", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Nashville", "state": "Tennessee" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT06654895" }, { "nct_id": "NCT02549716", "title": "Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Subarachnoid Hemorrhage", "Stroke" ], "interventions": [ { "name": "IV acetaminophen", "type": "DRUG" }, { "name": "Oral acetaminophen", "type": "DRUG" }, { "name": "Oral placebo", "type": "DRUG" }, { "name": "IV placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Milton S. Hershey Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2017-01-05", "completion_date": "2018-06-08", "has_results": true, "last_update_posted_date": "2019-04-10", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Hershey, Pennsylvania", "locations": [ { "city": "Hershey", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02549716" }, { "nct_id": "NCT01296711", "title": "Open-label Study to Assess the Safety and Efficacy of CDP6038 (Olokizumab) in Patients Who Completed RA0056", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "CDP6038 (olokizumab)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "UCB BIOSCIENCES, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 190, "start_date": "2011-03-07", "completion_date": "2013-08-05", "has_results": true, "last_update_posted_date": "2022-04-14", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 50, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 42 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Covina", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01296711" }, { "nct_id": "NCT05421208", "title": "Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Post-acute COVID-19 Syndrome", "Postural Tachycardia Syndrome (POTS)", "Long COVID", "SARS CoV 2 Infection" ], "interventions": [ { "name": "Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls", "type": "DIAGNOSTIC_TEST" }, { "name": "Levels of inflammatory cytokine ( IL-6) in controls", "type": "DIAGNOSTIC_TEST" }, { "name": "Effect on inflammation after chronic PNS stimulation", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2022-06-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-07-15", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05421208" }, { "nct_id": "NCT00085670", "title": "Cytokine Gene Polymorphisms in Bone Marrow Failure", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bone Marrow Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "2 Years to 80 Years" }, "enrollment_count": 79, "start_date": "2005-02-11", "completion_date": "2007-03-14", "has_results": false, "last_update_posted_date": "2020-09-10", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00085670" }, { "nct_id": "NCT01351805", "title": "Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Autoimmune Diseases", "Systemic Inflammatory Process", "Knee Pain Chronic", "Osteoarthritis", "Rheumatoid Arthritis" ], "interventions": [ { "name": "Fish Oil", "type": "DRUG" }, { "name": "Vitamin D", "type": "DIETARY_SUPPLEMENT" }, { "name": "placebo pill", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 25871, "start_date": "2010-07", "completion_date": "2025-02", "has_results": true, "last_update_posted_date": "2025-12-03", "last_synced_at": "2026-09-15T02:06:10.542Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01351805" } ] }