{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IOPI+device",
    "query": {
      "intervention": "IOPI device"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T20:28:03.573Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02962050",
      "title": "Delineating Swallowing Impairment and Decline in ALS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Videofluoroscopic Swallowing Study (VFSS)",
          "type": "PROCEDURE"
        },
        {
          "name": "Voluntary Peak Cough Flow Testing",
          "type": "DEVICE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "DEVICE"
        },
        {
          "name": "Capsaicin Challenge",
          "type": "DRUG"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "DEVICE"
        },
        {
          "name": "Eating Assessment Tool 10",
          "type": "OTHER"
        },
        {
          "name": "The Center for Neurologic Study Bulbar Function Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 109,
      "start_date": "2017-05-31",
      "completion_date": "2023-02-16",
      "has_results": false,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Tampa, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02962050"
    },
    {
      "nct_id": "NCT02710110",
      "title": "Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "PowerLung trainer",
          "type": "DEVICE"
        },
        {
          "name": "Micro Mouth Pressure Meter",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Videofluoroscopic swallowing study",
          "type": "PROCEDURE"
        },
        {
          "name": "Swallowing Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Iowa Oral Pressure Instrument",
          "type": "DEVICE"
        },
        {
          "name": "Capsaicin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2016-04",
      "completion_date": "2019-02-07",
      "has_results": false,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02710110"
    },
    {
      "nct_id": "NCT03682081",
      "title": "Interventions for Patients With Alzheimer's Disease and Dysphagia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Dysphagia",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI)",
          "type": "DEVICE"
        },
        {
          "name": "Biotene Oral Balance Gel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "50 Years to 99 Years"
      },
      "enrollment_count": 76,
      "start_date": "2020-09-25",
      "completion_date": "2025-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03682081"
    },
    {
      "nct_id": "NCT05304416",
      "title": "Clinical Markers of Dysphagia in Cardiac Surgical Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Diseases",
        "Dysphagia"
      ],
      "interventions": [
        {
          "name": "Fiberoptic Endoscopic Evaluation of Swallowing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Simultaneous FEES and Videofluoroscopy instrumental swallowing exam",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Videofluoroscopy instrumental swallowing exam (VFSS)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Voluntary Cough Peak Expiratory Flow (PEF) Testing",
          "type": "OTHER"
        },
        {
          "name": "Reflex Cough Screen",
          "type": "OTHER"
        },
        {
          "name": "Lingual Pressure Testing",
          "type": "OTHER"
        },
        {
          "name": "Speech Testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 347,
      "start_date": "2022-06-07",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Columbus, Ohio",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05304416"
    },
    {
      "nct_id": "NCT02564887",
      "title": "Pilot Study to Improve Therapeutic Outcomes for Dysphagia After Radiation Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysphagia",
        "Oral Pharyngeal Cancer"
      ],
      "interventions": [
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jonas Johnson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2016-01",
      "completion_date": "2019-09-06",
      "has_results": true,
      "last_update_posted_date": "2020-03-23",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02564887"
    },
    {
      "nct_id": "NCT04773184",
      "title": "Improving Diagnostic Standards in Dysphagia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dysphagia"
      ],
      "interventions": [
        {
          "name": "Fiberoptic Endoscopic Evaluation of Swallowing",
          "type": "PROCEDURE"
        },
        {
          "name": "Videofluoroscopic Swallowing Study",
          "type": "PROCEDURE"
        },
        {
          "name": "Voluntary Peak Cough Flow Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "PROCEDURE"
        },
        {
          "name": "Capsaicin Challenge",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Voicing Tasks",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 46,
      "start_date": "2021-04-27",
      "completion_date": "2023-09-23",
      "has_results": false,
      "last_update_posted_date": "2024-01-17",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04773184"
    },
    {
      "nct_id": "NCT07832266",
      "title": "Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cranial Nerve Injury",
        "Oropharyngeal Cancer"
      ],
      "interventions": [
        {
          "name": "Prednisone",
          "type": "DRUG"
        },
        {
          "name": "Ajovy",
          "type": "DRUG"
        },
        {
          "name": "Manual Therapy",
          "type": "OTHER"
        },
        {
          "name": "IOPI device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2027-03-01",
      "completion_date": "2032-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-21",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07832266"
    },
    {
      "nct_id": "NCT02710162",
      "title": "Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Micro Mouth Pressure Meter",
          "type": "DEVICE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "DEVICE"
        },
        {
          "name": "Electrical Impedance Myography",
          "type": "DEVICE"
        },
        {
          "name": "Capsaicin",
          "type": "DRUG"
        },
        {
          "name": "Videofluoroscopic Swallowing Study",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Swallowing Related Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Functional Oral Intake Scale",
          "type": "OTHER"
        },
        {
          "name": "Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised",
          "type": "OTHER"
        },
        {
          "name": "Eating Assessment Tool-10",
          "type": "OTHER"
        },
        {
          "name": "Communicative Effectiveness Survey",
          "type": "OTHER"
        },
        {
          "name": "The Center for Neurologic Studies Bulbar Function Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 21,
      "start_date": "2016-04",
      "completion_date": "2017-12-19",
      "has_results": false,
      "last_update_posted_date": "2017-12-21",
      "last_synced_at": "2026-09-23T20:28:03.573Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02710162"
    }
  ]
}